Search Results - "Bi, Xukun"

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  1. 1

    Endoplasmic Reticulum Chaperone GRP78 Protects Heart From Ischemia/Reperfusion Injury Through Akt Activation by Bi, Xukun, Zhang, Guangyu, Wang, Xiaoding, Nguyen, Chau, May, Herman I, Li, Xiaoting, Al-Hashimi, Ali A, Austin, Richard C, Gillette, Thomas G, Fu, Guosheng, Wang, Zhao V, Hill, Joseph A

    Published in Circulation research (25-05-2018)
    “…Restoration of coronary artery blood flow is the most effective means of ameliorating myocardial damage triggered by ischemic heart disease. However, coronary…”
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  2. 2

    Integrated Control of Fatty Acid Metabolism in Heart Failure by Li, Xiaoting, Bi, Xukun

    Published in Metabolites (29-04-2023)
    “…Disrupted fatty acid metabolism is one of the most important metabolic features in heart failure. The heart obtains energy from fatty acids via oxidation…”
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  3. 3

    Genetic Evidence for Causal Relationships between Plasma Eicosanoid Levels and Cardiovascular Disease by Bi, Xukun, Wang, Yiran, Lin, Yangjun, Wang, Meihui, Li, Xiaoting

    Published in Metabolites (23-05-2024)
    “…Cardiovascular diseases are the most common causes of mortality and disability worldwide. Eicosanoids are a group of bioactive metabolites that are mainly…”
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  4. 4

    Dendritic cell-mediated chronic low-grade inflammation is regulated by the RAGE-TLR4-PKCβ1 signaling pathway in diabetic atherosclerosis by Zhao, Liding, Li, Ya, Xu, Tian, Lv, Qingbo, Bi, Xukun, Liu, Xianglan, Fu, Guosheng, Zou, Yunzeng, Ge, Junbo, Chen, Zhaoyang, Zhang, Wenbin

    Published in Molecular medicine (Cambridge, Mass.) (21-01-2022)
    “…Abstract Background The unique mechanism of diabetic atherosclerosis has been a central research focus. Previous literature has reported that the inflammatory…”
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  5. 5

    Characterization of ferroptosis-triggered pyroptotic signaling in heart failure by Bi, Xukun, Wu, Xiaotian, Chen, Jiaqi, Li, Xiaoting, Lin, Yangjun, Yu, Yingying, Fang, Xuexian, Cheng, Xihao, Cai, Zhaoxian, Jin, Tingting, Han, Shuxian, Wang, Meihui, Han, Peidong, Min, Junxia, Fu, Guosheng, Wang, Fudi

    Published in Signal transduction and targeted therapy (25-09-2024)
    “…Pressure overload–induced cardiac hypertrophy is a common cause of heart failure (HF), and emerging evidence suggests that excessive oxidized lipids have a…”
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  6. 6

    iPLA2β Contributes to ER Stress-Induced Apoptosis during Myocardial Ischemia/Reperfusion Injury by Jin, Tingting, Lin, Jun, Gong, Yingchao, Bi, Xukun, Hu, Shasha, Lv, Qingbo, Chen, Jiaweng, Li, Xiaoting, Chen, Jiaqi, Zhang, Wenbin, Wang, Meihui, Fu, Guosheng

    Published in Cells (Basel, Switzerland) (09-06-2021)
    “…Both calcium-independent phospholipase A2 beta (iPLA2β) and endoplasmic reticulum (ER) stress regulate important pathophysiological processes including…”
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  7. 7

    The Rho kinase inhibitor, fasudil, ameliorates diabetes-induced cardiac dysfunction by improving calcium clearance and actin remodeling by Lai, Dongwu, Gao, Jing, Bi, Xukun, He, Hong, Shi, Xiaolu, Weng, Shaoxiang, Chen, Yu, Yang, Ying, Ye, Yang, Fu, Guosheng

    “…Previous study showed inhibition of RhoA and Rho kinase (ROCK) activity with fasudil could alleviate diabetes-induced cardiac dysfunction partially due to…”
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  8. 8

    GRP78 (Glucose-Regulated Protein of 78 kDa) Promotes Cardiomyocyte Growth Through Activation of GATA4 (GATA-Binding Protein 4) by Zhang, Guangyu, Wang, Xiaoding, Bi, Xukun, Li, Chao, Deng, Yingfeng, Al-Hashimi, Ali A, Luo, Xiang, Gillette, Thomas G, Austin, Richard C, Wang, Yanggan, Wang, Zhao V

    Published in Hypertension (Dallas, Tex. 1979) (01-02-2019)
    “…The heart manifests hypertrophic growth in response to elevation of afterload pressure. Cardiac myocyte growth involves new protein synthesis and membrane…”
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  9. 9

    Resveratrol prevents endothelial progenitor cells from senescence and reduces the oxidative reaction via PPAR-γ/HO-1 pathways by Shen, Xiaohua, Wang, Meihui, Bi, Xukun, Zhang, Jiefang, Wen, Shaoxiang, Fu, Guosheng, Xia, Liang

    Published in Molecular medicine reports (01-12-2016)
    “…Increasing evidence suggests endothelial progenitor cells (EPCs) improve neovascularization and endothelium regeneration. Resveratrol (RSV) is a natural…”
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  10. 10

    Glucose-regulated protein 78 is essential for cardiac myocyte survival by Wang, Xiaoding, Bi, Xukun, Zhang, Guangyu, Deng, Yingfeng, Luo, Xiang, Xu, Lin, Scherer, Philipp E., Ferdous, Anwarul, Fu, Guosheng, Gillette, Thomas G., Lee, Amy S., Jiang, Xuejun, Wang, Zhao V.

    Published in Cell death and differentiation (01-12-2018)
    “…Secretory and transmembrane proteins rely on proper function of the secretory pathway for folding, posttranslational modification, assembly, and secretion…”
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  11. 11

    Activation of liver X receptor attenuates lysophosphatidylcholine‐induced IL‐8 expression in endothelial cells via the NF‐κB pathway and SUMOylation by Bi, Xukun, Song, Jiale, Gao, Jing, Zhao, Juanjuan, Wang, Meihui, Scipione, Corey A., Koschinsky, Marlys L., Wang, Zhao V., Xu, Shiming, Fu, Guosheng

    Published in Journal of cellular and molecular medicine (01-12-2016)
    “…The liver X receptor (LXR) is a cholesterol‐sensing nuclear receptor that has an established function in lipid metabolism; however, its role in inflammation is…”
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  12. 12

    Apelin Ameliorates High Glucose-Induced Downregulation of Connexin 43 via AMPK-Dependent Pathway in Neonatal Rat Cardiomyocytes by Li, Xiaoting, Yu, Lu, Gao, Jing, Bi, Xukun, Zhang, Juhong, Xu, Shiming, Wang, Meihui, Chen, Mengmeng, Qiu, Fuyu, Fu, Guosheng

    Published in Aging and disease (01-02-2018)
    “…Diabetes Mellitus is a common disorder, with increasing risk of cardiac arrhythmias. Studies have shown that altered connexin expression and gap junction…”
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  13. 13

    Identification of differentially expressed genes in the endothelial precursor cells of patients with type 2 diabetes mellitus by bioinformatics analysis by Shen, Zhida, Chen, Qi, Ying, Hangying, Ma, Zetao, Bi, Xukun, Li, Xiaoting, Wang, Meihui, Jin, Chongying, Lai, Dongwu, Zhao, Yanbo, Fu, Guosheng

    Published in Experimental and therapeutic medicine (01-01-2020)
    “…Type 2 diabetes mellitus (DM) is a metabolic disease with worldwide prevalence that is associated with a decrease in the number and function of endothelial…”
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  14. 14
  15. 15

    GW25-e4550 Activation of Liver X receptor attenuates OxLDL-induced endothelial inflammation during atherosclerosis by Xukun, Bi, Zhengwei, Li, Jiale, Song, Jin, Gao, Meihui, Wang, Guosheng, Fu

    “…Oxidized low-density lipoprotein induced endothelial inflammation is the initial step during pathogenesis of atherosclerosis which trigger the expression of…”
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  16. 16

    Thymosin β4 promotes glucose-impaired endothelial progenitor cell function via Akt/endothelial nitric oxide synthesis signaling pathway by Qiu, Fuyu, Song, Jiale, Bi, Xukun, Wang, Meihui, Zhao, Yanbo, Fu, Guosheng

    Published in Experimental and therapeutic medicine (01-10-2018)
    “…Circulating endothelial progenitor cells (EPCs) are a subtype of hematopoietic stem cells, which can differentiate into endothelial cells and restore…”
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  17. 17

    Thymosin [beta]4 promotes glucose-impaired endothelial progenitor cell function via Akt/endothelial nitric oxide synthesis signaling pathway by Qiu, Fuyu, Song, Jiale, Bi, Xukun, Wang, Meihui, Zhao, Yanbo, Fu, Guosheng

    Published in Experimental and therapeutic medicine (01-10-2018)
    “…Circulating endothelial progenitor cells (EPCs) are a subtype of hematopoietic stem cells, which can differentiate into endothelial cells and restore…”
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  18. 18

    NADPH oxidase activation played a critical role in the oxidative stress process in stable coronary artery disease by Zhang, Jiefang, Wang, Meihui, Li, Zhengwei, Bi, Xukun, Song, Jiale, Weng, Shaoxiang, Fu, Guosheng

    Published in American journal of translational research (01-01-2016)
    “…The study was designed to investigate the oxidative stress levels of endothelial progenitor cells (EPCs) in stable coronary artery disease (CAD) and to explore…”
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  19. 19

    Thymosin [beta]4 promotes endothelial progenitor cell angiogenesis via a vascular endothelial growth factor-dependent mechanism by Zhao, Yanbo, Song, Jiale, Bi, Xukun, Gao, Jing, Shen, Zhida, Zhu, Junhui, Fu, Guosheng

    Published in Molecular medicine reports (01-08-2018)
    “…Endothelial progenitor cells (EPCs) are a promising cell source for tissue repair and regeneration, predominantly through angiogenesis promotion. Paracrine…”
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  20. 20

    Stromal cell-derived factor-1α prevents endothelial progenitor cells senescence and enhances re-endothelialization of injured arteries via human telomerase reverse transcriptase by Shen, Xiaohua, Zhou, Yucheng, Bi, Xukun, Zhang, Jiefang, Fu, Guosheng, Zheng, Hao

    Published in Cell biology international (01-08-2015)
    “…Recent studies have suggested that endothelial progenitor subpopulation (EPCs) number and activity were associated with EPCs senescence. Our previous study had…”
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