Search Results - "Bhuvanagiri, Madhuri"
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NMD: RNA biology meets human genetic medicine
Published in Biochemical journal (15-09-2010)“…NMD (nonsense-mediated mRNA decay) belongs to the best-studied mRNA surveillance systems of the cell, limiting the synthesis of truncated and potentially…”
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Proteomic Analysis Reveals Branch-specific Regulation of the Unfolded Protein Response by Nonsense-mediated mRNA Decay
Published in Molecular & cellular proteomics (01-05-2016)“…Nonsense-mediated mRNA decay (NMD) has originally been described as a surveillance mechanism to inhibit the expression of mRNAs with truncated open reading…”
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5‐azacytidine inhibits nonsense‐mediated decay in a MYC‐dependent fashion
Published in EMBO molecular medicine (01-12-2014)“…Nonsense‐mediated RNA decay (NMD) is an RNA‐based quality control mechanism that eliminates transcripts bearing premature translation termination codons (PTC)…”
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Improved binding site assignment by high-resolution mapping of RNA–protein interactions using iCLIP
Published in Nature communications (11-08-2015)“…Individual-nucleotide resolution crosslinking and immunoprecipitation (iCLIP) allows the determination of crosslinking sites of RNA-binding proteins (RBPs) on…”
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NF1 mRNA biogenesis: Effect of the genomic milieu in splicing regulation of the NF1 exon 37 region
Published in FEBS letters (07-08-2006)“…We have studied the splicing regulation of NF1 exons 36 and 37. We show that they not only require an intact exonic Splicing Enhancer (ESE) within exon 37, but…”
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The differential expression of alternatively polyadenylated transcripts is a common stress-induced response mechanism that modulates mammalian mRNA expression in a quantitative and qualitative fashion
Published in RNA (Cambridge) (01-09-2016)“…Stress adaptation plays a pivotal role in biological processes and requires tight regulation of gene expression. In this study, we explored the effect of…”
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