Search Results - "Bhowmik, Subhendu"
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Phosphorylation, oligomerization and self-assembly in water under potential prebiotic conditions
Published in Nature chemistry (01-02-2018)“…Prebiotic phosphorylation of (pre)biological substrates under aqueous conditions is a critical step in the origins of life. Previous investigations have had…”
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Trends in the Synthesis of Antimicrobial Derivatives by using the Gewald, Strecker, and Groebke-Blackburn-Bienaymé (GBB) Reactions
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-01-2024)“…Multicomponent reactions are highly useful in synthesizing natural products and bioactive molecules. Out of several MCRs, although utilized widely, some remain…”
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Nitrogenous Derivatives of Phosphorus and the Origins of Life: Plausible Prebiotic Phosphorylating Agents in Water
Published in Life (Basel, Switzerland) (29-07-2017)“…Phosphorylation under plausible prebiotic conditions continues to be one of the defining issues for the role of phosphorus in the origins of life processes. In…”
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An alternate route to substituted 6,7-dihydro 5H-dibenz[c,e]azepines from allylbenzamides derived from the Morita–Baylis–Hillman adducts
Published in Tetrahedron (01-07-2014)“…An acid-catalyzed modular synthesis of substituted 5H-dibenz[c,e]azepines from a biaryl allylbenzamides prepared from the MBH adducts via a cascade…”
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5
Design, synthesis, and evaluation of 1,4-benzothiazine-3-one containing bisamide derivatives as dual inhibitors of Staphylococcus aureus with plausible application in a urinary catheter
Published in Frontiers in chemistry (26-06-2024)“…In this study, 1,4-benzothiazine-based bisamide derivatives, a new class of antibacterial agents targeting bacterial peptide deformylase (PDF), were designed…”
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6
The role of sugar-backbone heterogeneity and chimeras in the simultaneous emergence of RNA and DNA
Published in Nature chemistry (01-11-2019)“…Hypotheses of the origins of RNA and DNA are generally centred on the prebiotic synthesis of a pristine system (pre-RNA or RNA), which gives rise to its…”
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Copper-catalysed one-pot cascade reaction strategy for the synthesis of benzoxazole-2-acrylic acid and benzoxazole-2‑propanoic acid derivatives
Published in Tetrahedron letters (06-06-2023)“…[Display omitted] A Cu-catalysed cascade strategy has been developed to synthesize benzoxazole-2-acrylic acid and benzoxazole-2‑propanoic acid derivatives in…”
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Morita-Baylis-Hillman Approach toward Formal Total Synthesis of Tamiflu and Total Synthesis of Gabaculine
Published in European journal of organic chemistry (01-11-2013)“…A Morita–Baylis–Hillman reaction mediated approach to the formal total synthesis of oseltamivir and the total synthesis of gabaculine is described. This…”
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Copper‐Catalyzed Chemoselective Synthesis of Pyrazolo‐Sulfonamide: Impact of Solvent on Nitro‐Pyrazole Reactivity
Published in European journal of organic chemistry (19-11-2024)“…This study presents a copper‐catalyzed, solvent‐dependent method for the rapid and efficient synthesis of N ‐pyrazolo‐sulfonamides directly from nitro‐pyrazole…”
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10
Regioselective Decarboxylative Transformations of Tetrahydro-β-carboline-1-carboxylic Acid: Reagent Controlled Selectivity toward Alkynylated or Enaminone Products
Published in Organic letters (13-10-2023)“…A one-pot, regioselective decarboxylative alkynylation of tetrahydro-β-carboline-1-carboxylic acid under peroxide-free condition is reported. The reaction is…”
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11
Synthesis of 3H‑Pyrazolo[3,4‑c]isoquinolines and Thieno[3,2‑c]isoquinolines via Cascade Imination/Intramolecular Decarboxylative Coupling
Published in Organic letters (04-10-2013)“…A general approach for the synthesis of 3H-pyrazolo[3,4-c]isoquinolines and thieno[3,2-c]isoquinolines is described involving the implementation of a cascade…”
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Substituent-Guided Switch between CH Activation and Decarboxylative Cross-Coupling during Palladium/Copper-Catalyzed Cascade Reactions of 2-Aminobenzoates with 2-Haloarylaldehydes
Published in Chemistry : a European journal (05-08-2013)“…Cascade switch: Phenanthridines, pyrazole[4,3‐c]quinolines and isocryptolepine were prepared in one step from the Pd/Cu‐catalyzed reaction between potassium…”
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13
Substituent-Guided Switch between CH Activation and Decarboxylative Cross-Coupling during Palladium/Copper-Catalyzed Cascade Reactions of 2-Aminobenzoates with 2-Haloarylaldehydes
Published in Chemistry : a European journal (05-08-2013)“…Cascade switch: Phenanthridines, pyrazole[4,3-c]quinolines and isocryptolepine were prepared in one step from the Pd/Cu-catalyzed reaction between potassium…”
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14
Synthesis of 3 H -Pyrazolo[3,4- c ]isoquinolines and Thieno[3,2- c ]isoquinolines via Cascade Imination/Intramolecular Decarboxylative Coupling
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15
Expeditious synthesis of chiral 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazines
Published in Tetrahedron letters (01-05-2013)“…An expeditious one-pot two-step synthesis of chiral 4-substituted-6-methyl-1,2-dihydropyrrolo[1,2-a]pyrazin-3(4H)-ones via reaction between 5-methyl…”
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An Efficient Combinatorial Synthesis of Allocolchicine Analogues via a Triple Cascade Reaction and their Evaluation as Inhibitors of Insulin Aggregation
Published in ChemMedChem (01-11-2013)“…A controlled cascade: A divergent, diastereoselective and efficient one‐pot synthesis of allocolchicinoids via a cascade Suzuki–Michael…”
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Application of Primary Allylamines from Morita-Baylis-Hillman Adducts: Cyanogen Azide Mediated Synthesis of Substituted 5-Aminotetrazoles and Their Attempted Transformation into Tetrazolo[1,5-a]pyrimidinones
Published in European Journal of Organic Chemistry (01-08-2010)“…A general protocol for the synthesis of substituted 5‐aminotetrazoles by treating cyanogen azide with primary allylamines afforded either by SN2 or SN2′…”
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