Search Results - "Bhowmick, Jayantika"
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Mechanistic insights into global suppressors of protein folding defects
Published in PLoS genetics (29-08-2022)“…Most amino acid substitutions in a protein either lead to partial loss-of-function or are near neutral. Several studies have shown the existence of second-site…”
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Backbone assignment of CcdB_G100T toxin from E.coli in complex with the toxin binding C-terminal domain of its cognate antitoxin CcdA
Published in Biomolecular NMR assignments (01-12-2024)“…The CcdAB system expressed in the E.coli cells is a prototypical example of the bacterial toxin-antitoxin (TA) systems that ensure the survival of the…”
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A CcdB toxin‐derived peptide acts as a broad‐spectrum antibacterial therapeutic in infected mice
Published in EMBO reports (05-07-2023)“…The bacterial toxin CcdB (Controller of Cell death or division B) targets DNA Gyrase, an essential bacterial topoisomerase, which is also the molecular target…”
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Journal Article