Search Results - "Bhide, Pradeep G."

Nicotine exposure of male mice produces behavioral impairment in multiple generations of descendants by McCarthy, Deirdre M, Morgan, Jr, Thomas J, Lowe, Sarah E, Williamson, Matthew J, Spencer, Thomas J, Biederman, Joseph, Bhide, Pradeep G

“…Use of tobacco products is injurious to health in men and women. However, tobacco use by pregnant women receives greater scrutiny because it can also…”
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Attention and working memory deficits in a perinatal nicotine exposure mouse model by Zhang, Lin, Spencer, Thomas J, Biederman, Joseph, Bhide, Pradeep G

“…Cigarette smoking by pregnant women is associated with a significant increase in the risk for cognitive disorders in their children. Preclinical models confirm…”
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Learning and memory deficits produced by aspartame are heritable via the paternal lineage by Jones, Sara K., McCarthy, Deirdre M., Stanwood, Gregg D., Schatschneider, Christopher, Bhide, Pradeep G.

“…Environmental exposures produce heritable traits that can linger in the population for one or two generations. Millions of individuals consume substances such…”
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Nicotine in Senescence and Atherosclerosis by Centner, Ann Marie, Bhide, Pradeep G, Salazar, Gloria

“…Cigarette smoke is a known exacerbator of age-related pathologies, such as cardiovascular disease (CVD), atherosclerosis, and cellular aging (senescence)…”
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Transgenerational transmission of hyperactivity in a mouse model of ADHD by Zhu, Jinmin, Lee, Kevin P, Spencer, Thomas J, Biederman, Joseph, Bhide, Pradeep G

“…Attention deficit hyperactivity disorder (ADHD) is a neurobehavioral disorder affecting children and adults. Genetic and environmental factors are associated…”
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Nicotine and the developing brain: Insights from preclinical models by McCarthy, Deirdre M., Zhang, Lin, Wilkes, Bradley J., Vaillancourt, David E., Biederman, Joseph, Bhide, Pradeep G.

“…Use of tobacco products during pregnancy is associated with increased risk for neurodevelopmental disorders in the offspring. Preclinical models of…”
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Modes and Mishaps of Neuronal Migration in the Mammalian Brain by Metin, Christine, Vallee, Richard B, Rakic, Pasko, Bhide, Pradeep G

“…The ability of neurons to migrate to their appropriate positions in the developing brain is critical to brain architecture and function. Recent research has…”
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A prenatal nicotine exposure mouse model of methylphenidate responsive ADHD-associated cognitive phenotypes by Zhu, Jinmin, Fan, Fangfang, McCarthy, Deirdre M., Zhang, Lin, Cannon, Elisa N., Spencer, Thomas J., Biederman, Joseph, Bhide, Pradeep G.

“…Prenatal exposure to nicotine via cigarette smoke or other forms of tobacco use is a significant environmental risk factor for attention deficit hyperactivity…”
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Behavioral, neurotransmitter and transcriptomic analyses in male and female Fmr1 KO mice by McCarthy, Deirdre M, Vied, Cynthia, Trupiano, Mia X, Canekeratne, Angeli J, Wang, Yuan, Schatschneider, Christopher, Bhide, Pradeep G

“…Fragile X syndrome is an inherited X-linked disorder associated with intellectual disabilities that begin in childhood and last a lifetime. The symptoms…”
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Compartment-specific transcription factors orchestrate angiogenesis gradients in the embryonic brain by Vasudevan, Anju, Long, Jason E, Crandall, James E, Rubenstein, John L R, Bhide, Pradeep G

“…Prevailing notions of cerebral vascularization imply that blood vessels sprout passively into the brain parenchyma from pial vascular plexuses to meet…”
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Dopamine receptor and Gα(olf) expression in DYT1 dystonia mouse models during postnatal development by Zhang, Lin, McCarthy, Deirdre M, Sharma, Nutan, Bhide, Pradeep G

“…DYT1 dystonia is a heritable, early-onset generalized movement disorder caused by a GAG deletion (ΔGAG) in the DYT1 gene. Neuroimaging studies and studies…”
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Dopamine receptor mRNA and protein expression in the mouse corpus striatum and cerebral cortex during pre- and postnatal development by Araki, Kiyomi Y, Sims, John R, Bhide, Pradeep G

“…Abstract The outcome of dopaminergic signaling and effectiveness of dopaminergic drugs depend on the relative preponderance of each of the five dopamine…”
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Nucleosome Repositioning: A Novel Mechanism for Nicotine- and Cocaine-Induced Epigenetic Changes by Brown, Amber N, Vied, Cynthia, Dennis, Jonathan H, Bhide, Pradeep G

“…Drugs of abuse modify behavior by altering gene expression in the brain. Gene expression can be regulated by changes in DNA methylation as well as by histone…”
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Behavioral and Neuroanatomical Consequences of Cell-Type Specific Loss of Dopamine D2 Receptors in the Mouse Cerebral Cortex by Lee, Gloria S, Graham, Devon L, Noble, Brenda L, Trammell, Taylor S, McCarthy, Deirdre M, Anderson, Lisa R, Rubinstein, Marcelo, Bhide, Pradeep G, Stanwood, Gregg D

“…Developmental dysregulation of dopamine D2 receptors (D2Rs) alters neuronal migration, differentiation, and behavior and contributes to the psychopathology of…”
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Cocaine-induced neurodevelopmental deficits and underlying mechanisms by Martin, Melissa M., Graham, Devon L., McCarthy, Deirdre M., Bhide, Pradeep G., Stanwood, Gregg D.

“…Exposure to drugs early in life has complex and long‐lasting implications for brain structure and function. This review summarizes work to date on the…”
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Dopamine Receptor Activation Modulates GABA Neuron Migration from the Basal Forebrain to the Cerebral Cortex by Crandall, James E, McCarthy, Deirdre M, Araki, Kiyomi Y, Sims, John R, Ren, Jia-Qian, Bhide, Pradeep G

“…GABA neurons of the cerebral cortex and other telencephalic structures are produced in the basal forebrain and migrate to their final destinations during the…”
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Acute plasmalemma permeability and protracted clearance of injured cells after controlled cortical impact in mice by Whalen, Michael J, Dalkara, Turgay, You, Zerong, Qiu, Jianhua, Bermpohl, Daniela, Mehta, Niyati, Suter, Bernhard, Bhide, Pradeep G, Lo, Eng H, Ericsson, Maria, Moskowitz, Michael A

“…Cell death after traumatic brain injury (TBI) evolves over days to weeks. Despite advances in understanding biochemical mechanisms that contribute to…”
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Dopamine Modulates Cell Cycle in the Lateral Ganglionic Eminence by Ohtani, Nobuyo, Goto, Tomohide, Waeber, Christian, Bhide, Pradeep G

“…Dopamine is a neuromodulator the functions of which in the regulation of complex behaviors such as mood, motivation, and attention are well known. Dopamine…”
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Retinoic acid influences neuronal migration from the ganglionic eminence to the cerebral cortex by Crandall, James E., Goodman, Timothy, McCarthy, Deirdre M., Duester, Gregg, Bhide, Pradeep G., Dräger, Ursula C., McCaffery, Peter

“…J. Neurochem. (2011) 119, 723–735. The ganglionic eminence contributes cells to several forebrain structures including the cerebral cortex, for which it…”
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Prenatal Cocaine Exposure Alters BDNF-TrkB Signaling in the Embryonic and Adult Brain by McCarthy, Deirdre M, Mueller, Kaly A, Cannon, Elisa N, Huizenga, Megan N, Darnell, Shayna B, Bhide, Pradeep G, Sadri-Vakili, Ghazaleh

“…Prenatal cocaine exposure remains a major public health concern because of its adverse effects on cognitive function. Although the molecular mechanisms…”
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