Search Results - "Bhide, Pradeep"

Nicotine exposure of male mice produces behavioral impairment in multiple generations of descendants by McCarthy, Deirdre M, Morgan, Jr, Thomas J, Lowe, Sarah E, Williamson, Matthew J, Spencer, Thomas J, Biederman, Joseph, Bhide, Pradeep G

“…Use of tobacco products is injurious to health in men and women. However, tobacco use by pregnant women receives greater scrutiny because it can also…”
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Attention and working memory deficits in a perinatal nicotine exposure mouse model by Zhang, Lin, Spencer, Thomas J, Biederman, Joseph, Bhide, Pradeep G

“…Cigarette smoking by pregnant women is associated with a significant increase in the risk for cognitive disorders in their children. Preclinical models confirm…”
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24.3 WORKING MEMORY DEFICITS IN A PRENATAL-NICOTINE-EXPOSURE MOUSE MODEL by Bhide, Pradeep, PhD

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Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala by Jones, Sara K, McCarthy, Deirdre M, Vied, Cynthia, Stanwood, Gregg D, Schatschneider, Chris, Bhide, Pradeep G

“…We report the effects of aspartame on anxiety-like behavior, neurotransmitter signaling and gene expression in the amygdala, a brain region associated with the…”
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Heritable consequences of paternal nicotine exposure: from phenomena to mechanisms by McCarthy, Deirdre M., Bhide, Pradeep G.

“…Our understanding of the interactions between genetic and environmental factors in shaping behavioral phenotypes has expanded to include environment-induced…”
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Nicotine in Senescence and Atherosclerosis by Centner, Ann Marie, Bhide, Pradeep G, Salazar, Gloria

“…Cigarette smoke is a known exacerbator of age-related pathologies, such as cardiovascular disease (CVD), atherosclerosis, and cellular aging (senescence)…”
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Learning and memory deficits produced by aspartame are heritable via the paternal lineage by Jones, Sara K., McCarthy, Deirdre M., Stanwood, Gregg D., Schatschneider, Christopher, Bhide, Pradeep G.

“…Environmental exposures produce heritable traits that can linger in the population for one or two generations. Millions of individuals consume substances such…”
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Reply to Charles V. Vorhees: Aspartame and anxiety-like behavior by Jones, Sara K, McCarthy, Deirdre M, Vied, Cynthia, Stanwood, Gregg D, Schatschneider, Chris, Bhide, Pradeep G

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Nicotine and the developing brain: Insights from preclinical models by McCarthy, Deirdre M., Zhang, Lin, Wilkes, Bradley J., Vaillancourt, David E., Biederman, Joseph, Bhide, Pradeep G.

“…Use of tobacco products during pregnancy is associated with increased risk for neurodevelopmental disorders in the offspring. Preclinical models of…”
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Hippocampal neuroinflammation following combined exposure to cyclophosphamide and naproxen in ovariectomized mice by Pavlock, Samantha, McCarthy, Deirdre M., Kesarwani, Anisha, Jean-Pierre, Pascal, Bhide, Pradeep G.

“…Aim: Cancer patients undergoing chemotherapy report cognitive changes collectively termed "chemo brain." Neuroinflammation is among the factors believed to…”
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Preclinical Models of Attention Deficit Hyperactivity Disorder: Neurobiology, Drug Discovery, and Beyond by McCarthy, Deirdre M., Spencer, Thomas J., Bhide, Pradeep G.

“…Objective: We offer an overview of ADHD research using mouse models of nicotine exposure. Method: Nicotine exposure of C57BL/6 or Swiss Webster mice occurred…”
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Transgenerational transmission of hyperactivity in a mouse model of ADHD by Zhu, Jinmin, Lee, Kevin P, Spencer, Thomas J, Biederman, Joseph, Bhide, Pradeep G

“…Attention deficit hyperactivity disorder (ADHD) is a neurobehavioral disorder affecting children and adults. Genetic and environmental factors are associated…”
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Modes and Mishaps of Neuronal Migration in the Mammalian Brain by Metin, Christine, Vallee, Richard B, Rakic, Pasko, Bhide, Pradeep G

“…The ability of neurons to migrate to their appropriate positions in the developing brain is critical to brain architecture and function. Recent research has…”
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Frontal Cortical Monoamine Release, Attention, and Working Memory in a Perinatal Nicotine Exposure Mouse Model Following Kappa Opioid Receptor Antagonism by Zhang, Lin, McCarthy, Deirdre M, Eskow Jaunarajs, Karen L, Biederman, Joseph, Spencer, Thomas J, Bhide, Pradeep G

“…Perinatal nicotine exposure (PNE) produces frontal cortical hypo-dopaminergic state and attention and working memory deficits consistent with…”
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The adenosine A(2A) receptor agonist CGS 21680 alleviates auditory sensorimotor gating deficits and increases in accumbal CREB in rats neonatally treated with quinpirole by Brown, Russell W., Bhide, Pradeep G., Gill, W. Drew, Peeters, Loren D.

“…Rationale and objective The adenosine A(2A) receptor forms a mutually inhibitory heteromer with the dopamine D 2 receptor, and A(2A) agonists decrease D 2…”
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Dopamine receptor and Gα(olf) expression in DYT1 dystonia mouse models during postnatal development by Zhang, Lin, McCarthy, Deirdre M, Sharma, Nutan, Bhide, Pradeep G

“…DYT1 dystonia is a heritable, early-onset generalized movement disorder caused by a GAG deletion (ΔGAG) in the DYT1 gene. Neuroimaging studies and studies…”
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Effects of Developmental Nicotine Exposure on Frontal Cortical GABA-to-Non-GABA Neuron Ratio and Novelty-Seeking Behavior by Martin, Melissa M, McCarthy, Deirdre M, Schatschneider, Chris, Trupiano, Mia X, Jones, Sara K, Kalluri, Aishani, Bhide, Pradeep G

“…Abstract Cigarette smoking during pregnancy is a major public health concern, resulting in detrimental health effects in the mother and her offspring. The…”
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A prenatal nicotine exposure mouse model of methylphenidate responsive ADHD-associated cognitive phenotypes by Zhu, Jinmin, Fan, Fangfang, McCarthy, Deirdre M., Zhang, Lin, Cannon, Elisa N., Spencer, Thomas J., Biederman, Joseph, Bhide, Pradeep G.

“…Prenatal exposure to nicotine via cigarette smoke or other forms of tobacco use is a significant environmental risk factor for attention deficit hyperactivity…”
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Behavioral, neurotransmitter and transcriptomic analyses in male and female Fmr1 KO mice by McCarthy, Deirdre M, Vied, Cynthia, Trupiano, Mia X, Canekeratne, Angeli J, Wang, Yuan, Schatschneider, Christopher, Bhide, Pradeep G

“…Fragile X syndrome is an inherited X-linked disorder associated with intellectual disabilities that begin in childhood and last a lifetime. The symptoms…”
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Nucleosome Repositioning: A Novel Mechanism for Nicotine- and Cocaine-Induced Epigenetic Changes by Brown, Amber N, Vied, Cynthia, Dennis, Jonathan H, Bhide, Pradeep G

“…Drugs of abuse modify behavior by altering gene expression in the brain. Gene expression can be regulated by changes in DNA methylation as well as by histone…”
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