Search Results - "Bhawsar, Satish"
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Synthesis and evaluation of novel biaryl oxazolidinones effective against gram-positive bacterial infections
Published in Medicinal chemistry research (01-10-2024)“…Oxazolidinones are synthetic antibiotic class of compounds characterized by chemical structure, cyclic carbamate with ‘ S’ configuration of substituent at C -5…”
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Nafithromycin (MIQNAF®): ultramodern lactone ketolide designed to treat community acquired bacterial pneumonia (CABP)
Published in Medicinal chemistry research (01-10-2024)“…Community acquired bacterial pneumoniae (CABP) infections is the major cause of mortality and morbidity, especially in elderly patients. India accounts for 23%…”
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A Chiral Benzoquinolizine-2-carboxylic Acid Arginine Salt Active against Vancomycin-Resistant Staphylococcus aureus
Published in Journal of medicinal chemistry (11-08-2005)“…There is an urgent medical need for novel antibacterial agents to treat hospital infections, specially those caused by multidrug-resistant Gram-positive…”
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Design and synthesis of an oral prodrug alalevonadifloxacin for the treatment of MRSA infection
Published in Bioorganic & medicinal chemistry letters (15-12-2021)“…Injectable and oral prodrug of levonadifloxacin with widely differing solubility and oral bioavailability. [Display omitted] Levonadifloxacin is a parenteral…”
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WCK 4034: A promising oxazolidinone for treating gram positive infections
Published in Bioorganic & medicinal chemistry letters (01-09-2022)“…[Display omitted] Increased resistance to gram positive infections have highlighted the limitations of currently available drug treatments including…”
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WCK 1152, WCK 1153: Discovery and structure activity relationship for the treatment of resistant pneumococcal and staphylococcal respiratory infections
Published in Bioorganic & medicinal chemistry letters (01-05-2022)“…[Display omitted] Novel antibacterial agents needed constantly to counter the ever emergent resistance development to commercially available drugs; one of the…”
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A Chiral Benzoquinolizine-2-carboxylic Acid Arginine Salt Active against Vancomycin-Resistant Staphylococcus a ureus
Published in Journal of medicinal chemistry (11-08-2005)“…There is an urgent medical need for novel antibacterial agents to treat hospital infections, specially those caused by multidrug-resistant Gram-positive…”
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Journal Article