Search Results - "Bhave, Vishakha S"

Role of PINCH and its partner tumor suppressor Rsu-1 in regulating liver size and tumorigenesis by Donthamsetty, Shashikiran, Bhave, Vishakha S, Mars, Wendy M, Bowen, William C, Orr, Anne, Haynes, Meagan M, Wu, Chuanyue, Michalopoulos, George K

“…Particularly interesting new cysteine-histidine-rich protein (PINCH) protein is part of the ternary complex known as the IPP (integrin linked kinase…”
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Hepatocyte proliferation and hepatomegaly induced by phenobarbital and 1,4‐bis [2‐(3,5‐dichloropyridyloxy)] benzene is suppressed in hepatocyte‐targeted glypican 3 transgenic mice by Lin, Chih‐Wen, Mars, Wendy M., Paranjpe, Shirish, Donthamsetty, Shashikiran, Bhave, Vishakha S., Kang, Liang‐I, Orr, Anne, Bowen, William C., Bell, Aaron W., Michalopoulos, George K.

“…Glypican 3 (GPC3) is a family of glycosylphosphatidylinositol‐anchored, cell‐surface heparan sulfate proteoglycans. Loss‐of‐function mutations of GPC3 cause…”
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Secretory phospholipase A2-mediated progression of hepatotoxicity initiated by acetaminophen is exacerbated in the absence of hepatic COX-2 by BHAVE, Vishakha S, DONTHAMSETTY, Shashikiran, LATENDRESSE, John R, CUNNINGHAM, Michael L, MEHENDALE, Harihara M

“…We have previously reported that among the other death proteins, hepatic secretory phospholipase A₂ (sPLA₂) is a leading mediator of progression of liver…”
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Regulation of Liver Growth by Glypican 3, CD81, Hedgehog, and Hhex by Bhave, Vishakha S, Mars, Wendy, Donthamsetty, Shashikiran, Zhang, Xiyue, Tan, Langzhu, Luo, Jianhua, Bowen, William C, Michalopoulos, George K

“…Previous studies from our laboratory have found glypican 3 (GPC3) as a negative regulator of growth. CD81 was found to be a binding partner for GPC3, and its…”
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Genes inducing iPS phenotype play a role in hepatocyte survival and proliferation in vitro and liver regeneration in vivo by Bhave, Vishakha S., Paranjpe, Shirish, Bowen, William C., Donthamsetty, Shashikiran, Bell, Aaron W., Khillan, Jaspal S., Michalopoulos, George K.

“…Reprogramming factors have been used to induce pluripotent stem cells as an alternative to somatic cell nuclear transfer technology in studies targeting…”
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Oct4 Is Crucial for Transdifferentiation of Hepatocytes to Biliary Epithelial Cells in an In Vitro Organoid Culture Model by Doffou, Mboya, Adams, George, Bowen, William C., Paranjpe, Shirish, Parihar, Harish S., Nguyen, Huy, Michalopoulos, George K., Bhave, Vishakha S.

“…Hepatocyte to biliary transdifferentiation has been documented in various models of bile duct injury. In this process, mature hepatocytes transform into mature…”
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Nonalcoholic fatty liver sensitizes rats to carbon tetrachloride hepatotoxicity by Donthamsetty, Shashikiran, Bhave, Vishakha S., Mitra, Mayurranjan S., Latendresse, John R., Mehendale, Harihara M.

“…This study tested whether hepatic steatosis sensitizes liver to toxicant‐induced injury and investigated the potential mechanisms of hepatotoxic sensitivity…”
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Excessive hepatomegaly of mice with hepatocyte‐targeted elimination of integrin linked kinase following treatment with 1,4‐bis [2‐(3,5‐dichaloropyridyloxy)] benzene by Donthamsetty, Shashikiran, Bhave, Vishakha S., Kliment, Corrine S., Bowen, William C., Mars, Wendy M., Bell, Aaron W., Stewart, Rachel E., Orr, Anne, Wu, Chuanyue, Michalopoulos, George K.

“…TCBOPOP (1,4‐bis [2‐(3,5‐dichaloropyridyloxy)] benzene) an agonist of the constitutive androstane receptor (CAR), produces rapid hepatocyte hyperplasia and…”
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Inhibition of cyclooxygenase-2 aggravates secretory phospholipase A2-mediated progression of acute liver injury by BHAVE, Vishakha S, DONTHAMSETTY, Shashikiran, LATENDRESSE, John R, MEHENDALE, Harihara M

“…Our previous study [Bhave, V. S., Donthamsetty, S., Latendresse, J. R., Muskhelishvili, L., and Mehendale, H. M. 2008-this issue. Secretory phospholipase A(2)…”
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Secretory phospholipase A2 mediates progression of acute liver injury in the absence of sufficient cyclooxygenase-2 by BHAVE, Vishakha S, DONTHAMSETTY, Shashikiran, LATENDRESSE, John R, MUSKHELISHVILI, Levan, MEHENDALE, Harihara M

“…Previous studies have shown that injury initiated by toxicants progresses even after most of the toxicant is eliminated from the body. One mechanism of…”
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Upregulation of calpastatin in regenerating and developing rat liver: Role in resistance against hepatotoxicity by Limaye, Pallavi B., Bhave, Vishakha S., Palkar, Prajakta S., Apte, Udayan M., Sawant, Sharmilee P., Yu, Songtao, Latendresse, John R., Reddy, Janardan K., Mehendale, Harihara M.

“…Acute liver failure induced by hepatotoxic drugs results from rapid progression of injury. Substantial research has shown that timely liver regeneration can…”
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The Role of Lipocalin‐2 (LCN2) and High Mobility Box Group 1 (HMGB1) in Acetaminophen‐induced Acute Liver Failure by Reed, E'Joven D., Shashidharamurthy, Rangaiah, Bhave, Vishakha S.

“…Acetaminophen (APAP) overdose is the most common cause of Acute Liver Failure (ALF). Following APAP overdose, toxicity is initiated by the conversion of APAP…”
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Secretory phospholipase A{sub 2}-mediated progression of hepatotoxicity initiated by acetaminophen is exacerbated in the absence of hepatic COX-2 by Bhave, Vishakha S., Donthamsetty, Shashikiran, Latendresse, John R., Cunningham, Michael L., Mehendale, Harihara M.

“…We have previously reported that among the other death proteins, hepatic secretory phospholipase A{sub 2} (sPLA{sub 2}) is a leading mediator of progression of…”
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Excessive hepatomegaly of mice with hepatocyte‐targeted elimination of integrin linked kinase following treatment with 1,4‐bis [2‐(3,5‐dichaloropyridyloxy)] benzene

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Inhibition of cyclooxygenase-2 aggravates secretory phospholipase A{sub 2}-mediated progression of acute liver injury by Bhave, Vishakha S., Donthamsetty, Shashikiran, Latendresse, John R., Mehendale, Harihara M.

“…Our previous study [Bhave, V. S., Donthamsetty, S., Latendresse, J. R., Muskhelishvili, L., and Mehendale, H. M. 2008-this issue. Secretory phospholipase A{sub…”
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Secretory phospholipase A{sub 2} mediates progression of acute liver injury in the absence of sufficient cyclooxygenase-2 by Bhave, Vishakha S., Donthamsetty, Shashikiran, Latendresse, John R., Muskhelishvili, Levan, Mehendale, Harihara M.

“…Previous studies have shown that injury initiated by toxicants progresses even after most of the toxicant is eliminated from the body. One mechanism of…”
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Secretory phospholipase A 2-mediated progression of hepatotoxicity initiated by acetaminophen is exacerbated in the absence of hepatic COX-2 by Bhave, Vishakha S., Donthamsetty, Shashikiran, Latendresse, John R., Cunningham, Michael L., Mehendale, Harihara M.

“…We have previously reported that among the other death proteins, hepatic secretory phospholipase A 2 (sPLA 2) is a leading mediator of progression of liver…”
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Inhibition of RE‐1 silencing transcription factor (REST) inhibits survival and proliferation of primary hepatocytes under the influence of hepatocye growth factor (HGF) and epidermal growth factor (EGF) by Bhave, Vishakha S., Bowen, William C., Paranjpe, Shirish G., Donthamsetty, Shashikiran, Michalopoulos, George K.

“…The objective of the present work was to test the expression and role of REST in primary hepatocytes under the influence of growth factors HGF and EGF. REST…”
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Nonalcoholic steatohepatitic (NASH) mice are protected from higher hepatotoxicity of acetaminophen upon induction of PPARα with clofibrate by Donthamsetty, Shashikiran, Bhave, Vishakha S., Mitra, Mayurranjan S., Latendresse, John R., Mehendale, Harihara M.

“…The objective was to investigate if the hepatotoxic sensitivity in nonalcoholic steatohepatitic mice to acetaminophen (APAP) is due to downregulation of…”
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Excessive Hepatomegaly of Mice with Hepatocyte-Targeted Elimination of Integrin Linked Kinase Following Treatment by TCPOBOP by Donthamsetty, Shashikiran, Bhave, Vishakha S., Kliment, Corrine S, Bowen, William C., Mars, Wendy M., Bell, Aaron W., Stewart, Rachel E, Orr, Anne, Wu, Chuanyue, Michalopoulos, George K.

“…TCBOPOP (1, 4-bis [2-(3, 5-dichaloropyridyloxy)] benzene) an agonist of the Constitutive Androstane receptor (CAR), produces rapid hepatocyte hyperplasia and…”
Get full text