Search Results - "Bhattarai, Shristi"
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Quadruple-negative breast cancer: novel implications for a new disease
Published in Breast cancer research : BCR (19-11-2020)“…Based on the androgen receptor (AR) expression, triple-negative breast cancer (TNBC) can be subdivided into AR-positive TNBC and AR-negative TNBC, also known…”
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2
PLK1 and AURKB phosphorylate survivin differentially to affect proliferation in racially distinct triple-negative breast cancer
Published in Cell death & disease (10-01-2023)“…Protein diversity due to alternative mRNA splicing or post-translational modifications (PTMs) plays a vital role in various cellular functions. The mitotic…”
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3
A novel prognostic two-gene signature for triple negative breast cancer
Published in Modern pathology (01-11-2020)“…The absence of a robust risk stratification tool for triple negative breast cancer (TNBC) underlies imprecise and nonselective treatment of these patients with…”
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4
Exosomal Metabolic Signatures Are Associated with Differential Response to Neoadjuvant Chemotherapy in Patients with Breast Cancer
Published in International journal of molecular sciences (10-05-2022)“…Neoadjuvant chemotherapy (NAC) is commonly used in breast cancer (BC) patients to increase eligibility for breast-conserving surgery. Only 30% of patients with…”
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5
Digital image analysis and machine learning-assisted prediction of neoadjuvant chemotherapy response in triple-negative breast cancer
Published in Breast cancer research : BCR (18-01-2024)“…Pathological complete response (pCR) is associated with favorable prognosis in patients with triple-negative breast cancer (TNBC). However, only 30-40% of TNBC…”
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6
Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers
Published in Scientific reports (20-02-2020)“…Epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 3 (HER3) have been investigated as triple-negative breast cancer (TNBC)…”
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7
QNBC Is Associated with High Genomic Instability Characterized by Copy Number Alterations and miRNA Deregulation
Published in International journal of molecular sciences (26-10-2021)“…Triple-negative breast cancer (TNBC) can be further classified into androgen receptor (AR)-positive TNBC and AR-negative TNBC or quadruple-negative breast…”
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8
Quadruple-Negative Breast Cancer: An Uneven Playing Field
Published in JCO global oncology (01-11-2020)Get full text
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9
Predicting Metastasis Risk in Pancreatic Neuroendocrine Tumors Using Deep Learning Image Analysis
Published in Frontiers in oncology (25-02-2021)“…The prognosis of patients with pancreatic neuroendocrine tumors (PanNET), the second most common type of pancreatic cancer, varies significantly, and up to 15%…”
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10
Extremely Elevated Prostate-Specific Antigen in Acute Prostatitis: A Case Report
Published in Curēus (Palo Alto, CA) (18-08-2023)“…Elevated prostate-specific antigen (PSA) levels are mostly suggestive of prostate cancer, but they are elevated in non-cancerous prostatic conditions as well…”
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11
Prevalence and Mortality of Triple-Negative Breast Cancer in West Africa: Biologic and Sociocultural Factors
Published in JCO global oncology (01-07-2021)Get full text
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12
A Case Series Exploration of Multi-Regional Expression Heterogeneity in Triple-Negative Breast Cancer Patients
Published in International journal of molecular sciences (01-11-2022)“…Extensive intratumoral heterogeneity (ITH) is believed to contribute to therapeutic failure and tumor recurrence, as treatment-resistant cell clones can…”
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13
Deep learning based registration of serial whole-slide histopathology images in different stains
Published in Journal of pathology informatics (01-01-2023)“…For routine pathology diagnosis and imaging-based biomedical research, Whole-slide image (WSI) analyses have been largely limited to a 2D tissue image space…”
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14
Associations between health insurance status, neighborhood deprivation, and treatment delays in women with breast cancer living in Georgia
Published in Cancer medicine (Malden, MA) (01-08-2023)“…Background Little is known regarding the association between insurance status and treatment delays in women with breast cancer and whether this association…”
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15
Preclinical Development of a Nontoxic Oral Formulation of Monoethanolamine, a Lipid Precursor, for Prostate Cancer Treatment
Published in Clinical cancer research (15-07-2017)“…Most currently available chemotherapeutic agents target rampant cell division in cancer cells, thereby affecting rapidly dividing normal cells resulting in…”
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16
Predicting Neoadjuvant Treatment Response in Triple-Negative Breast Cancer Using Machine Learning
Published in Diagnostics (Basel) (01-01-2024)“…Neoadjuvant chemotherapy (NAC) is the standard treatment for early-stage triple negative breast cancer (TNBC). The primary endpoint of NAC is a pathological…”
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17
Cell cycle traverse rate predicts long-term outcomes in a multi-institutional cohort of patients with triple-negative breast cancer
Published in BJC reports (13-11-2024)“…Background Ki67 index (KI) and mitotic index (MI) are proliferation markers with established prognostic value in breast carcinomas. While KI is evaluated…”
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Abstract C101: A prognostic risk model for African American women with breast cancer: Implications for meaningful accrual in clinical trials
Published in Cancer epidemiology, biomarkers & prevention (01-06-2020)“…Background: Racial disparities in breast cancer outcomes appear to be widening in the US despite multiple advancements in breast cancer (BC) management…”
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Abstract P3-09-13: Androgen receptor loss is associated with genomic instability characterized by copy number alterations and mirna deregulation in triple-negative breast cancer
Published in Cancer research (Chicago, Ill.) (15-02-2022)“…Background: Triple-negative breast cancer (TNBC) comprises 10%-20% of invasive breast carcinoma cases. Patients with TNBC exhibit poorer 5-year survival and…”
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Abstract P2-12-24: Exosomal metabolic signatures are associated with differential response to neoadjuvant chemotherapy in patients with breast cancer
Published in Cancer research (Chicago, Ill.) (15-02-2022)“…Background: Neoadjuvant chemotherapy (NAC) is becoming the standard of care for aggressive breast cancer (BC). In patients with BC, NAC can increase…”
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