Search Results - "Bhattacharyya, Anusri Mitra"

The Aggregation State of Rhodanese during Folding Influences the Ability of GroEL to Assist Reactivation by Bhattacharyya, A M, Horowitz, P M

“…The in vitro folding of rhodanese involves a competition between formation of properly folded enzyme and off-pathway inactive species. Co-solvents like…”
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Alteration Around the Active Site of Rhodanese during Urea-induced Denaturation and Its Implications for Folding by Bhattacharyya, Anusri Mitra, Horowitz, Paul

“…The enzyme rhodanese contains two globular domains connected by a tether region and associated by strong hydrophobic interactions. The protein has proven to be…”
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Active Rhodanese Lacking Nonessential Sulfhydryl Groups Contains an Unstable C-terminal Domain and Can Be Bound, Inactivated, and Reactivated by GroEL by Ybarra, Jesse, Bhattacharyya, Anusri Mitra, Panda, Markandeswar, Horowitz, Paul M.

“…Mutation of all nonessential cysteine residues in rhodanese turns the enzyme into a form (C3S) that is fully active but less stable than wild type (WT). This…”
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Rhodanese Can Partially Refold in Its GroEL−GroES−ADP Complex and Can Be Released to Give a Homogeneous Product by Bhattacharyya, Anusri Mitra, Horowitz, Paul M

“…Molecular chaperones GroEL and GroES facilitate reactivation of denatured rhodanese which folds poorly unless the process is assisted. The present work tests…”
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Isolation and Characterization of Rhodanese Intermediates during Thermal Inactivation and Their Implications for the Mechanism of Protein Aggregation by Bhattacharyya, Anusri Mitra, Horowitz, Paul M

“…The initial steps of heat-induced inactivation and aggregation of the enzyme rhodanese have been studied and found to involve the early formation of modified…”
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