Search Results - "Bhattacharya, Pratip K."

Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis by Rupaimoole, Rajesha, Lee, Jaehyuk, Haemmerle, Monika, Ling, Hui, Previs, Rebecca A., Pradeep, Sunila, Wu, Sherry Y., Ivan, Cristina, Ferracin, Manuela, Dennison, Jennifer B., Millward, Niki M. Zacharias, Nagaraja, Archana S., Gharpure, Kshipra M., McGuire, Michael, Sam, Nidhin, Armaiz-Pena, Guillermo N., Sadaoui, Nouara C., Rodriguez-Aguayo, Cristian, Calin, George A., Drapkin, Ronny I., Kovacs, Jeffery, Mills, Gordon B., Zhang, Wei, Lopez-Berestein, Gabriel, Bhattacharya, Pratip K., Sood, Anil K.

“…Long noncoding RNAs (lncRNAs) significantly influence the development and regulation of genome expression in cells. Here, we demonstrate the role of lncRNA…”
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A mechanistic modeling framework reveals the key principles underlying tumor metabolism by Tripathi, Shubham, Park, Jun Hyoung, Pudakalakatti, Shivanand, Bhattacharya, Pratip K, Kaipparettu, Benny Abraham, Levine, Herbert

“…While aerobic glycolysis, or the Warburg effect, has for a long time been considered a hallmark of tumor metabolism, recent studies have revealed a far more…”
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Editorial: Metabolic regulation under oxidative stress in cancer by Subramani, Elavarasan, Dominic, Abishai, Bhattacharya, Pratip K., Frigo, Daniel E., Bederman, Ilya, Vaziri-Gohar, Ali

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Identifying the Metabolic Signatures of PPARD-Overexpressing Gastric Tumors by Pudakalakatti, Shivanand, Titus, Mark, Enriquez, José S, Ramachandran, Sumankalai, Zacharias, Niki M, Shureiqi, Imad, Liu, Yi, Yao, James C, Zuo, Xiangsheng, Bhattacharya, Pratip K

“…Peroxisome proliferator-activated receptor delta (PPARD) is a nuclear receptor known to play an essential role in regulation of cell metabolism, cell…”
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Combining Hyperpolarized Real-Time Metabolic Imaging and NMR Spectroscopy To Identify Metabolic Biomarkers in Pancreatic Cancer by Dutta, Prasanta, Perez, Mayrim R, Lee, Jaehyuk, Kang, Yaan, Pratt, Michael, Salzillo, Travis C, Weygand, Joseph, Zacharias, Niki M, Gammon, Seth T, Koay, Eugene J, Kim, Michael, McAllister, Florencia, Sen, Subrata, Maitra, Anirban, Piwnica-Worms, David, Fleming, Jason B, Bhattacharya, Pratip K

“…Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer that progresses without any symptom, and oftentimes, it is detected at an advanced stage. The lack…”
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Hyperpolarized Magnetic Resonance Imaging, Nuclear Magnetic Resonance Metabolomics, and Artificial Intelligence to Interrogate the Metabolic Evolution of Glioblastoma by Hsieh, Kang Lin, Chen, Qing, Salzillo, Travis C, Zhang, Jian, Jiang, Xiaoqian, Bhattacharya, Pratip K, Shams, Shyan

“…Glioblastoma (GBM) is a malignant Grade VI cancer type with a median survival duration of only 8-16 months. Earlier detection of GBM could enable more…”
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Beyond Colonoscopy: Exploring New Cell Surface Biomarkers for Detection of Early, Heterogenous Colorectal Lesions by Ramezani, Saleh, Parkhideh, Arianna, Bhattacharya, Pratip K., Farach-Carson, Mary C., Harrington, Daniel A.

“…Colorectal cancer (CRC) is the third leading cause of cancer-related deaths among both men and women in the United States. Early detection and surgical removal…”
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Early Detection of Pancreatic Intraepithelial Neoplasias (PanINs) in Transgenic Mouse Model by Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy by Dutta, Prasanta, Castro Pando, Susana, Mascaro, Marilina, Riquelme, Erick, Zoltan, Michelle, Zacharias, Niki M., Gammon, Seth T., Piwnica-Worms, David, Pagel, Mark D., Sen, Subrata, Maitra, Anirban, Shams, Shayan, McAllister, Florencia, Bhattacharya, Pratip K.

“…While pancreatic cancer (PC) survival rates have recently shown modest improvement, the disease remains largely incurable. Early detection of pancreatic cancer…”
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Oxidative Damage by Ruthenium Complexes Containing the Dipyridophenazine Ligand or Its Derivatives:  A Focus on Intercalation by Delaney, Sarah, Pascaly, Matthias, Bhattacharya, Pratip K, Han, Koun, Barton, Jacqueline K

“…Interactions with DNA by a family of ruthenium(II) complexes bearing the dppz (dppz = dipyridophenazine) ligand or its derivatives have been examined. The…”
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Hyperpolarized Magnetic Resonance and Artificial Intelligence: Frontiers of Imaging in Pancreatic Cancer by Enriquez, José S, Chu, Yan, Pudakalakatti, Shivanand, Hsieh, Kang Lin, Salmon, Duncan, Dutta, Prasanta, Millward, Niki Zacharias, Lurie, Eugene, Millward, Steven, McAllister, Florencia, Maitra, Anirban, Sen, Subrata, Killary, Ann, Zhang, Jian, Jiang, Xiaoqian, Bhattacharya, Pratip K, Shams, Shayan

“…There is an unmet need for noninvasive imaging markers that can help identify the aggressive subtype(s) of pancreatic ductal adenocarcinoma (PDAC) at diagnosis…”
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Measuring the Metabolic Evolution of Glioblastoma throughout Tumor Development, Regression, and Recurrence with Hyperpolarized Magnetic Resonance by Salzillo, Travis C, Mawoneke, Vimbai, Weygand, Joseph, Shetty, Akaanksh, Gumin, Joy, Zacharias, Niki M, Gammon, Seth T, Piwnica-Worms, David, Fuller, Gregory N, Logothetis, Christopher J, Lang, Frederick F, Bhattacharya, Pratip K

“…Rapid diagnosis and therapeutic monitoring of aggressive diseases such as glioblastoma can improve patient survival by providing physicians the time to…”
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Assessing Therapeutic Efficacy in Real-time by Hyperpolarized Magnetic Resonance Metabolic Imaging by Dutta, Prasanta, Salzillo, Travis C, Pudakalakatti, Shivanand, Gammon, Seth T, Kaipparettu, Benny A, McAllister, Florencia, Wagner, Shawn, Frigo, Daniel E, Logothetis, Christopher J, Zacharias, Niki M, Bhattacharya, Pratip K

“…Precisely measuring tumor-associated alterations in metabolism clinically will enable the efficient assessment of therapeutic responses. Advances in imaging…”
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Post-Acquisition Hyperpolarized 29Silicon Magnetic Resonance Image Processing for Visualization of Colorectal Lesions Using a User-Friendly Graphical Interface by McCowan, Caitlin V., Salmon, Duncan, Hu, Jingzhe, Pudakalakatti, Shivanand, Whiting, Nicholas, Davis, Jennifer S., Carson, Daniel D., Zacharias, Niki M., Bhattacharya, Pratip K., Farach-Carson, Mary C.

“…Medical imaging devices often use automated processing that creates and displays a self-normalized image. When improperly executed, normalization can…”
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NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors by Pudakalakatti, Shivanand, Audia, Alessandra, Mukhopadhyay, Anirudh, Enriquez, José S., Bourgeois, Dontrey, Tayob, Nabihah, Zacharias, Niki M., Millward, Steven W., Carson, Daniel, Farach-Carson, Mary C., Lang, Frederick F., Heimberger, Amy B., Bhat, Krishna P., Bhattacharya, Pratip K.

“…“Tumor-educated platelets” have recently generated substantial interest for the diagnosis of cancer. We hypothesized that tumor educated platelets from…”
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Interrogating Metabolism in Brain Cancer by Salzillo, Travis C., BS, Hu, Jingzhe, BS, Nguyen, Linda, BS, Whiting, Nicholas, PhD, Lee, Jaehyuk, PhD, Weygand, Joseph, BS, Dutta, Prasanta, PhD, Pudakalakatti, Shivanand, PhD, Millward, Niki Zacharias, PhD, Gammon, Seth T., PhD, Lang, Frederick F., MD, Heimberger, Amy B., MD, Bhattacharya, Pratip K., PhD

“…This article reviews existing and emerging techniques of interrogating metabolism in brain cancer from well-established proton magnetic resonance spectroscopy…”
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Influence of Intervening Mismatches on Long-Range Guanine Oxidation in DNA Duplexes by Bhattacharya, Pratip K, Barton, Jacqueline K

“…A systematic investigation of the efficiency of oxidative damage at guanine residues through long-range charge transport was carried out as a function of…”
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Unlocking ferroptosis in prostate cancer — the road to novel therapies and imaging markers by Cao, Pham Hong Anh, Dominic, Abishai, Lujan, Fabiola Ester, Senthilkumar, Sanjanaa, Bhattacharya, Pratip K., Frigo, Daniel E., Subramani, Elavarasan

“…Ferroptosis is a distinct form of regulated cell death that is predominantly driven by the build-up of intracellular iron and lipid peroxides. Ferroptosis…”
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Metabolic Differences in Glutamine Utilization Lead to Metabolic Vulnerabilities in Prostate Cancer by Zacharias, Niki Marie, McCullough, Christopher, Shanmugavelandy, Sriram, Lee, Jaehyuk, Lee, Youngbok, Dutta, Prasanta, McHenry, James, Nguyen, Linda, Norton, William, Jones, Lawrence W., Bhattacharya, Pratip K.

“…The new oncologic paradigm of precision medicine is focused on identifying metabolic, proteomic, transcriptomic and genomic variabilities in tumors that can be…”
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Assessing Metabolic Intervention with a Glutaminase Inhibitor in Real-Time by Hyperpolarized Magnetic Resonance in Acute Myeloid Leukemia by Zacharias, Niki M, Baran, Natalia, Shanmugavelandy, Sriram S, Lee, Jaehyuk, Lujan, Juliana Velez, Dutta, Prasanta, Millward, Steven W, Cai, Tianyu, Wood, Christopher G, Piwnica-Worms, David, Konopleva, Marina, Bhattacharya, Pratip K

“…Acute myeloid leukemia (AML) is an aggressive hematopoietic disease characterized by glutamine-dependent metabolism. A novel glutaminase (GLS) inhibitor,…”
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Metabolic Imaging Using Hyperpolarization for Assessment of Premalignancy by Pudakalakatti, Shivanand, Raj, Priyank, Salzillo, Travis C, Enriquez, José S, Bourgeois, Dontrey, Dutta, Prasanta, Titus, Mark, Shams, Shayan, Bhosale, Priya, Kim, Michael, McAllister, Florencia, Bhattacharya, Pratip K

“…There is an unmet need for noninvasive surrogate markers that can help identify premalignant lesions across different tumor types. Here we describe the…”
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