Search Results - "Bhatta, R. S."

Assessment of Clinical Pharmacokinetic Drug-Drug Interaction of Antimalarial Drugs α/β-Arteether and Sulfadoxine-Pyrimethamine by Chhonker, Y S, Bhosale, V V, Sonkar, S K, Chandasana, H, Kumar, D, Vaish, S, Choudhary, S C, Bhadhuria, S, Sharma, S, Singh, R K, Jain, G K, Vaish, A K, Gaur, S P S, Bhatta, R S

“…Antimalarial drug combination therapy is now being widely used for the treatment of uncomplicated malaria. The objective of the present study was to…”
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Bioanalytical method development and validation of natamycin in rabbit tears and its application to ocular pharmacokinetic studies by Bhatta, R.S., Chandasana, H., Rathi, C., Kumar, D., Chhonker, Y.S., Jain, G.K.

“…A new selective and sensitive high-performance liquid chromatography coupled with tandem mass spectrometry (LC–MS/MS) method was developed for the…”
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Mucoadhesive nanoparticles for prolonged ocular delivery of natamycin: In vitro and pharmacokinetics studies by Bhatta, R.S., Chandasana, H., Chhonker, Y.S., Rathi, C., Kumar, D., Mitra, K., Shukla, P.K.

“…The aim of this study was to prepare natamycin encapsulated lecithin/chitosan mucoadhesive nanoparticles (NPs) for prolonged ocular application. These NPs were…”
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Chebulinic acid alleviates LPS-induced inflammatory bone loss by targeting the crosstalk between reactive oxygen species/NFκB signaling in osteoblast cells by Sharma, Kriti, Kumar, Shiv, Prakash, Ravi, Khanka, Sonu, Mishra, Tripti, Rathur, Rajat, Biswas, Arpon, Verma, Sarvesh Kumar, Bhatta, R.S., Narender, T., Singh, Divya

“…Chebulinic acid (CA), a plant ellagitannin derived from Triphala, is reported to exhibit both anti-inflammatory & anti-oxidant activity apart from anti-tumour…”
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Identification of quinoline-chalcone hybrids as potential antiulcer agents by Sashidhara, Koneni V., Avula, Srinivasa Rao, Mishra, Vaibhav, Palnati, Gopal Reddy, Singh, L. Ravithej, Singh, Neetu, Chhonker, Yashpal S., Swami, Priyanka, Bhatta, R.S., palit, Gautam

“…Antiulcer activity of novel quinoline-chalcone hybrids (13–37) was investigated. Among them, eight compounds (14, 16, 17, 23, 29, 31, 32 and 35) were found to…”
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Quantifying the sensation of temperature: A new method for evaluating the thermal behaviour of building materials by Bhatta, S.R., Tiippana, K., Vahtikari, K., Kiviluoma, P., Hughes, M., Kyttä, M.

“…•The psychophysical method was used to quantify the subjective perception of temperature.•Pinewood, oakwood, and ceramic tiles are compared on thermal touch…”
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Pyranocarbazoles from Murraya koenigii (L.) Spreng. as antimicrobial agents by Joshi, Trapti, Jain, Tushar, Mahar, Rohit, Singh, Sumit K., Srivastava, Piush, Shukla, Sanjeev K., Mishra, Dipak K., Bhatta, R. S., Banerjee, Dibyendu, Kanojiya, Sanjeev

“…The bioassay guided fractionation of methanolic extract of Murraya koenigii (L.) Spreng. leaves resulted in the isolation of seven pyranocarbazoles. These were…”
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Synthesis, biological evaluation, and molecular docking study of some new rohitukine analogs as protein tyrosine phosphatase 1B inhibitors by Balaramnavar, V.M., Srivastava, R., Varshney, S., Kumar, S., Rawat, A.K., Chandasana, H., Chhonker, Y.S., Bhatta, R.S., Srivastava, A.K., Gaikwad, A.N., Lakshmi, V., Saxena, A.K.

“…[Display omitted] •The paper describes a novel antidiabetic molecule derived from natural product Rohitukine acting through novel target PTP1B.•The molecule…”
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Pharmacokinetics, Tissue Distribution and Plasma Protein Binding Studies of Rohitukine: A Potent Anti-hyperlipidemic Agent by Chhonker, Y S, Chandasana, H, Kumar, A, Kumar, D, Laxman, T S, Mishra, S K, Balaramnavar, V M, Srivastava, S, Saxena, A K, Bhatta, R S

“…Rohitukine (RH) is a chromone alkaloid considered as one of the major active component of Dysoxylum binectariferum, exhibiting diverse pharmacological…”
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Pelvic girdle pain during pregnancy and puerperium by Keriakos, R., Bhatta, S. R. Chaudhuri, Morris, F., Mason, S., Buckley, S.

“…Pelvic girdle pain (PGP) is a term used specifically to pregnancy-related pain in the lumbosacral, sacroiliac and symphysis pubis joints. Pregnancy-induced…”
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Molecular Characterization and Computational Modelling of New Delhi Metallo-β-Lactamase-5 from an Escherichia coli Isolate (KOEC3) of Bovine Origin by Purkait, D., Ahuja, A., Bhattacharjee, U., Singha, A., Rhetso, K., Dey, T. K., Das, S., Sanjukta, R. K., Puro, K., Shakuntala, I., Sen, A., Banerjee, A., Sharma, I., Bhatta, R. S., Mawlong, M., Guha, C., Pradhan, N. R., Ghatak, S.

“…Emergence of antimicrobial resistance mediated through New Delhi metallo-β-lactamases (NDMs) is a serious therapeutic challenge. Till date, 16 different NDMs…”
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Simultaneous estimation of E- and Z-isomers of guggulsterone in rabbit plasma using liquid chromatography tandem mass spectrometry and its application to pharmacokinetic study by Bhatta, R. S., Kumar, D., Chhonker, Y. S., Jain, G. K.

“…A sensitive and selective liquid chromatography/tandem mass spectrometric method was developed for simultaneous determination of E‐ and Z‐guggulsterone isomers…”
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Quantitative analysis of bioactive carbazole alkaloids in Murraya koenigii by Joshi, Trapti, Mahar, Rohit, Singh, Sumit K, Srivastava, Piush, Shukla, Sanjeev K, Mishra, Dipak K, Bhatta, R S, Kanojiya, Sanjeev

“…Carbazole alkaloids induce apoptosis in HL-60 cells through activation of the caspase-9/caspase-3 pathway and they are targeted as potential anticancer agents…”
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Simultaneous estimation of 16α-hydroxycleroda-3,13(14) Z-dien-15,16-olide from Polyalthia longifolia and its metabolite in hamster plasma: application to pharmacokinetic study by Bhatta, R. S., Kumar, Devendra, Chhonker, Y. S., Kumar, Deepak, Singh, Suriya P., Sashidhara, Koneni V., Jain, G. K.

“…ABSTRACT A selective and sensitive LC–MS‐MS method was developed and validated for simultaneous estimation and pharmacokinetic studies of…”
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Bioanalytical method development and validation of novel antithrombotic agent S002-333 by LC-MS/MS and its application to pharmacokinetic studies by Bhatta, R. S., Kumar, D., Chhonker, Y. S., Saxena, A. K., Jain, G. K.

“…A rapid, sensitive and simple liquid chromatography‐tandem mass spectrometry (LC‐MS/MS) method using an electrospray ionization (ECI) source for the…”
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Bioanalytical method development and validation for simultaneous estimation of (R)- and (S)-isomers of S002-333: a potent novel anti-thrombotic agent using LC–MS/MS by Bhatta, R. S., Chhonker, Y. S., Kumar, D., Saxena, A. K., Jain, G. K.

“…A selective, sensitive, and high throughput liquid chromatography–tandem mass spectrometry (LC–MS/MS) method has been developed and validated for the…”
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Molecular Characterization and Computational Modelling of New Delhi Metallo-[beta]-Lactamase-5 from an Escherichia coli Isolate (KOEC3) of Bovine Origin by Purkait, D, Ahuja, A, Bhattacharjee, U, Singha, A, Rhetso, K, Dey, T K, Das, S, Sanjukta, R K, Puro, K, Shakuntala, I, Sen, A, Banerjee, A, Sharma, I, Bhatta, R S, Mawlong, M, Guha, C, Pradhan, N R, Ghatak, S

“…Emergence of antimicrobial resistance mediated through New Delhi metallo-[beta]-lactamases (NDMs) is a serious therapeutic challenge. Till date, 16 different…”
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Influence of Temperature and pH on Fermentation Pattern and Methane Production in the Rumen Simulating Fermenter (RUSITEC) by Bhatta, R, Tajima, K, Kurihara, M

“…An experiment was conducted to study the effect of temperature and pH on in vitro nutrient degradability, volatile fatty acid profile and methane production…”
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