Search Results - "Bhatnagar, Suyash"

Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis by Istvan, Eva S, Das, Sudipta, Bhatnagar, Suyash, Beck, Josh R, Owen, Edward, Llinas, Manuel, Ganesan, Suresh M, Niles, Jacquin C, Winzeler, Elizabeth, Vaidya, Akhil B, Goldberg, Daniel E

“…parasites possess a protein with homology to Niemann-Pick Type C1 proteins (Niemann-Pick Type C1-Related protein, NCR1). We isolated parasites with…”
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Metabolic responses in blood-stage malaria parasites associated with increased and decreased sensitivity to PfATP4 inhibitors by Tewari, Shivendra G, Elahi, Rubayet, Kwan, Bobby, Rajaram, Krithika, Bhatnagar, Suyash, Reifman, Jaques, Prigge, Sean T, Vaidya, Akhil B, Wallqvist, Anders

“…Spiroindolone and pyrazoleamide antimalarial compounds target Plasmodium falciparum P-type ATPase (PfATP4) and induce disruption of intracellular Na…”
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Dramatic Consequences of Reducing Erythrocyte Membrane Cholesterol on Plasmodium falciparum by Ahiya, Avantika I, Bhatnagar, Suyash, Morrisey, Joanne M, Beck, Josh R, Vaidya, Akhil B

“…Cholesterol is the most abundant lipid in the erythrocyte. During its blood-stage development, the malaria parasite establishes an active cholesterol gradient…”
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Diverse Chemical Compounds Target Plasmodium falciparum Plasma Membrane Lipid Homeostasis by Bhatnagar, Suyash, Nicklas, Sezin, Morrisey, Joanne M, Goldberg, Daniel E, Vaidya, Akhil B

“…Lipid homeostasis is essential to the maintenance of life. We previously reported that disruptions of the parasite Na+ homeostasis via inhibition of PfATP4…”
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Investigating Na+ and Lipid Homeostasis as Targets for Antimalarial Drugs by Bhatnagar, Suyash

“…In an effort to combat the emerging resistance towards front line anti-malarials, novel therapeutics have been discovered that target the parasite’s Na +…”
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Development of Deep Learning Model for Cardiac Arrhythmia Detection from ECG by Mohammed Fahad, R. A., Purohit, Saffalaya, Bhatnagar, Suyash, Kotambkar, Deepali M., Thakre, Vinod M., Kapoor, Karan

“…An irregular heartbeat or abnormal cardiac rhythm is an arrhythmia. The heart can efficiently pump blood throughout the body when it beats regularly (rhythmic…”
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