Search Results - "Bhatnagar, Parijat"

Primary T‐cell‐based delivery platform for in vivo synthesis of engineered proteins by Radhakrishnan, Harikrishnan, Newmyer, Sherri L., Ssemadaali, Marvin A., Javitz, Harold S., Bhatnagar, Parijat

“…Primary T cell has been transformed into a cell‐based delivery platform that synthesizes complex biologics at the disease site with spatiotemporal resolution…”
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Cell-Based Platform for Antigen Testing and Its Application for SARS-CoV-2 Infection by Ssemadaali, Marvin A., Newmyer, Sherri, Radhakrishnan, Harikrishnan, Arredondo, Juan, Javitz, Harold S., Dandekar, Satya, Bhatnagar, Parijat

“…We have engineered a cell that can be used for diagnosing active severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. Isolation of…”
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Electrically regulated cell‐based intervention for viral infections by Newmyer, Sherri, Ssemadaali, Marvin A., Radhakrishnan, Harikrishnan, Javitz, Harold S., Bhatnagar, Parijat

“…This work reports on an engineered cell that—when electrically stimulated—synthesizes a desired protein, that is, ES‐Biofactory. The platform has been used to…”
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Genetically engineered pair of cells for serological testing and its application for SARS‐CoV‐2 by Ssemadaali, Marvin A., Arredondo, Juan, Buser, Elise A., Newmyer, Sherri, Radhakrishnan, Harikrishnan, Javitz, Harold S., Dandekar, Satya, Bhatnagar, Parijat

“…We have developed a serology test platform for identifying individuals with prior exposure to specific viral infections and provide data to help reduce public…”
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Engineered CD4 T cells for in vivo delivery of therapeutic proteins by Radhakrishnan, Harikrishnan, Newmyer, Sherri L, Javitz, Harold S, Bhatnagar, Parijat

“…The CD4 T cell, when engineered with a chimeric antigen receptor (CAR) containing specific intracellular domains, has been transformed into a zero-order…”
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Multiplexed electrospray deposition for protein microarray with micromachined silicon device by Bhatnagar, Parijat

“…Multiplexed electrospray deposition device capable of delivering picoliter volumes made by silicon micromachining technology has been developed as a deposition…”
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Abstract 2557: Assessing the therapeutic efficacy of disease-specific T-cell biofactories by Repellin, Claire E., Patel, Puja, Beviglia, Lucia, Javitz, Harold, Sambucetti, Lidia C., Bhatnagar, Parijat

“…Current protein-based cancer therapies have several disadvantages, which include general toxicity, lack of response at the administered dose and differing…”
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Multiplexed electrospray deposition for protein microarraywith micromachined silicon device by Bhatnagar, Parijat

“…Multiplexed electrospray deposition device capable of delivering picoliter volumes made by silicon micromachining technology has been developed as a deposition…”
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NK‐Cell Biofactory as an Off‐the‐Shelf Cell‐based Vector for Targeted In Situ Synthesis of Engineered Proteins by Repellin, Claire E., Ssemadaali, Marvin A., Newmyer, Sherri, Radhakrishnan, Harikrishnan, Javitz, Harold S., Bhatnagar, Parijat

“…The NK‐92MI, a fast‐growing cytolytic cell line with a track record of exerting clinical efficacy, is transformed into a vector for synthesizing calibrated…”
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Multiplexed Protein Patterns on a Photosensitive Hydrophilic Polymer Matrix by Bhatnagar, Parijat, Malliaras, George G., Kim, Il, Batt, Carl A.

“…A photosensitive hydrogel film containing a photocleavable protecting group is attached to silicon oxide. Projection photolithography is used to generate…”
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Tumor Lysing Genetically Engineered T Cells Loaded with Multi-Modal Imaging Agents by Bhatnagar, Parijat, Alauddin, Mian, Bankson, James A., Kirui, Dickson, Seifi, Payam, Huls, Helen, Lee, Dean A., Babakhani, Aydin, Ferrari, Mauro, Li, King C., Cooper, Laurence J. N.

“…Genetically-modified T cells expressing chimeric antigen receptors (CAR) exert anti-tumor effect by identifying tumor-associated antigen (TAA), independent of…”
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Imaging of genetically engineered T cells by PET using gold nanoparticles complexed to Copper-64 by Bhatnagar, Parijat, Li, Zheng, Choi, Yoonsu, Guo, Jianfeng, Li, Feng, Lee, Daniel Y, Figliola, Matthew, Huls, Helen, Lee, Dean A, Zal, Tomasz, Li, King C, Cooper, Laurence J N

“…Adoptive transfer of primary T cells genetically modified to have desired specificity can exert an anti-tumor response in some patients. To improve our…”
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Bionanofabrication of Metallic and Semiconductor Nanoparticle Arrays Using S-Layer Protein Lattices with Different Lateral Spacings and Geometries by Mark, Sonny S, Bergkvist, Magnus, Yang, Xin, Teixeira, Leonardo M, Bhatnagar, Parijat, Angert, Esther R, Batt, Carl A

“…Two-dimensional (2-D) surface layer (S-layer) protein lattices isolated from the Gram-positive bacterium Deinococcus radiodurans and the acidothermophilic…”
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Combination of Gene Therapy and Nanoparticle Imaging for Improving T-Cell Therapy by Choi, Yoonsu, Li, Zheng, Wang, Xukui, Li, Hui, Li, Feng, Lee, Daniel Y, Bhatnagar, Parijat, Tung, Ching H, Biswal, Sibani L, Lee, Dean A., Li, King C, Cooper, Laurence J.N.

“…Abstract 1479 Despite a functioning immune system, malignant tumors develop strategies to avoid immune recognition and elimination by T cells. Gene therapy can…”
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Integrated reactive ion etching to pattern cross-linked hydrophilic polymer structures for protein immobilization by Bhatnagar, Parijat, Strickland, Aaron D., Kim, Il, Malliaras, George G., Batt, Carl A.

“…Patterning of cross-linked hydrophilic polymer features using reactive ion etching (RIE) capable of covalently immobilizing proteins has been achieved…”
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Protein functionalized micro hydrogel features for cell–surface interaction by Bhatnagar, Parijat, Nixon, Alan J., Kim, Il, Kameoka, Jun

“…Cross-linked hydrogel features have been patterned using subtractive lift-off of polymerized hydrogel film. Projection lithography and oxygen plasma etch was…”
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Selective electrodeposition of zinc–nickel alloy through porous medium by Bhatnagar, Parijat, Free, Michael L.

“…The ‘portable electrodeposition’ method described in this work differs from the conventional brush plating method in that it utilizes a reservoir that contains…”
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Imaging of Genetically Engineered T Cells by PET using Gold Nanoparticle Complexed to Copper-64 by Bhatnagar, Parijat, Li, Zheng, Choi, Yoonsu, Guo, Jianfeng, Li, Feng, Lee, Daniel Y, Figliola, Matthew, Huls, Helen, Lee, Dean A., Zal, Tomasz, Li, King C, Cooper, Laurence JN

“…Adoptive transfer of primary T cells genetically modified to have desired specificity can exert an anti-tumor response in some patients. To improve our…”
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Thin film processing using S-layer proteins: Biotemplated assembly of colloidal gold etch masks for fabrication of silicon nanopillar arrays by Mark, Sonny S., Bergkvist, Magnus, Bhatnagar, Parijat, Welch, Colin, Goodyear, Andrew L., Yang, Xin, Angert, Esther R., Batt, Carl A.

“…We explored the bionanofabrication of silicon nanopillar structures using ordered gold nanoparticle arrays generated from microbial surface layer (S-layer)…”
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Imaging of genetically engineered T cells by PET using gold nanoparticles complexed to Copper-64Electronic supplementary information (ESI) available. See DOI: 10.1039/c2ib20093g by Bhatnagar, Parijat, Li, Zheng, Choi, Yoonsu, Guo, Jianfeng, Li, Feng, Lee, Daniel Y, Figliola, Matthew, Huls, Helen, Lee, Dean A, Zal, Tomasz, Li, King C, Cooper, Laurence J. N

“…Adoptive transfer of primary T cells genetically modified to have desired specificity can exert an anti-tumor response in some patients. To improve our…”
Get full text