Search Results - "Bhatnagar, Namrata"

The ALKF1174L Mutation Potentiates the Oncogenic Activity of MYCN in Neuroblastoma by Berry, Teeara, Luther, William, Bhatnagar, Namrata, Jamin, Yann, Poon, Evon, Sanda, Takaomi, Pei, Desheng, Sharma, Bandana, Vetharoy, Winston R., Hallsworth, Albert, Ahmad, Zai, Barker, Karen, Moreau, Lisa, Webber, Hannah, Wang, Wenchao, Liu, Qingsong, Perez-Atayde, Antonio, Rodig, Scott, Cheung, Nai-Kong, Raynaud, Florence, Hallberg, Bengt, Robinson, Simon P., Gray, Nathanael S., Pearson, Andrew D.J., Eccles, Suzanne A., Chesler, Louis, George, Rani E.

“…The ALKF1174L mutation is associated with intrinsic and acquired resistance to crizotinib and cosegregates with MYCN in neuroblastoma. In this study, we…”
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The ALK(F1174L) mutation potentiates the oncogenic activity of MYCN in neuroblastoma by Berry, Teeara, Luther, William, Bhatnagar, Namrata, Jamin, Yann, Poon, Evon, Sanda, Takaomi, Pei, Desheng, Sharma, Bandana, Vetharoy, Winston R, Hallsworth, Albert, Ahmad, Zai, Barker, Karen, Moreau, Lisa, Webber, Hannah, Wang, Wenchao, Liu, Qingsong, Perez-Atayde, Antonio, Rodig, Scott, Cheung, Nai-Kong, Raynaud, Florence, Hallberg, Bengt, Robinson, Simon P, Gray, Nathanael S, Pearson, Andrew D J, Eccles, Suzanne A, Chesler, Louis, George, Rani E

“…The ALK(F1174L) mutation is associated with intrinsic and acquired resistance to crizotinib and cosegregates with MYCN in neuroblastoma. In this study, we…”
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Molecular rationale for the use of PI3K/AKT/mTOR pathway inhibitors in combination with crizotinib in ALK-mutated neuroblastoma by Moore, Nathan F, Azarova, Anna M, Bhatnagar, Namrata, Ross, Kenneth N, Drake, Lauren E, Frumm, Stacey, Liu, Qinsong S, Christie, Amanda L, Sanda, Takaomi, Chesler, Louis, Kung, Andrew L, Gray, Nathanael S, Stegmaier, Kimberly, George, Rani E

“…Mutations in the ALK tyrosine kinase receptor gene represent important therapeutic targets in neuroblastoma, yet their clinical translation has been…”
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3,3'-diindolylmethane enhances the efficacy of butyrate in colon cancer prevention through down-regulation of survivin by Bhatnagar, Namrata, Li, Xia, Chen, Yue, Zhou, Xudong, Garrett, Scott H, Guo, Bin

“…Butyrate is an inhibitor of histone deacetylase (HDAC) and has been extensively evaluated as a chemoprevention agent for colon cancer. We recently showed that…”
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Abstract 4454: The AXL tyrosine kinase receptor contributes to ALK-inhibitor resistance in neuroblastoma by Bhatnagar, Namrata, Luther, William, Sharma, Bandana, Liu, Qingsong, Gray, Nathanael, George, Rani E.

“…Abstract The crizotinib-resistant ALKF1174L mutation occurs de novo in neuroblastoma (NB) and as an acquired mechanism of resistance in ALK…”
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Mutations that disrupt PHOXB interaction with the neuronal calcium sensor HPCAL1 impede cellular differentiation in neuroblastoma by Wang, W, Zhong, Q, Teng, L, Bhatnagar, N, Sharma, B, Zhang, X, Luther, W, Haynes, L P, Burgoyne, R D, Vidal, M, Volchenboum, S, Hill, D E, George, R E

“…Heterozygous germline mutations in PHOX2B , a transcriptional regulator of sympathetic neuronal differentiation, predispose to diseases of the sympathetic…”
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Abstract 2935: The ATP-competitive mTOR inhibitor Torin2 enhances sensitivity of the ALK F1174L mutation to crizotinib in neuroblastoma by Azarova, Anna M., Bhatnagar, Namrata, Olsen-Drake, Lauren, Ross, Kenneth, Frumm, Stacey, Liu, Qingsong, Christie, Amanda, Sanda, Takaomi, Rodig, Scott J., Christensen, James G., Kung, Andrew L., Gray, Nathanael, Stegmaier, Kimberley, George, Rani E.

“…Abstract Mutations in the anaplastic lymphoma kinase (ALK) receptor represent an important therapeutic target in neuroblastoma. The most frequently occurring…”
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3,3′‐Diindolylmethane Enhances the Efficacy of Butyrate in Colon Cancer Prevention through Down‐regulation of Survivin by Bhatnagar, Namrata, Li, Xia, Chen, Yue, Zhou, Xudong, Garrett, Scott H, Guo, Bin

“…Abstract only Butyrate is an inhibitor of histone deacetylase (HDAC) and has been extensively evaluated as a chemoprevention agent for colon cancer. We…”
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Regulation of prostate cancer apoptosis and response to chemotherapy by miR-205 and miR-31 by Bhatnagar, Namrata

“…Prostate cancer is the most common form of cancer amongst men in the United States and ranks second in being the major leading cause of death due to cancer in…”
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