Search Results - "Bhatia, Sumati"

Pathogen Inhibition by Multivalent Ligand Architectures by Bhatia, Sumati, Camacho, Luis Cuellar, Haag, Rainer

“…Interfacial multivalent interactions at pathogen–cell interfaces can be competitively inhibited by multivalent scaffolds that prevent pathogen adhesion to the…”
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Linear polysialoside outperforms dendritic analogs for inhibition of influenza virus infection in vitro and in vivo by Bhatia, Sumati, Lauster, Daniel, Bardua, Markus, Ludwig, Kai, Angioletti-Uberti, Stefano, Popp, Nicole, Hoffmann, Ute, Paulus, Florian, Budt, Matthias, Stadtmüller, Marlena, Wolff, Thorsten, Hamann, Alf, Böttcher, Christoph, Herrmann, Andreas, Haag, Rainer

“…Abstract Inhibition of influenza A virus infection by multivalent sialic acid inhibitors preventing viral hemagglutinin binding to host cells of the…”
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Quantification of Multivalent Interactions between Sialic Acid and Influenza A Virus Spike Proteins by Single-Molecule Force Spectroscopy by Cuellar-Camacho, Jose Luis, Bhatia, Sumati, Reiter-Scherer, Valentin, Lauster, Daniel, Liese, Susanne, Rabe, Jürgen P, Herrmann, Andreas, Haag, Rainer

“…Multivalency is a key principle in reinforcing reversible molecular interactions through the formation of multiple bonds. The influenza A virus deploys this…”
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Force Spectroscopy Shows Dynamic Binding of Influenza Hemagglutinin and Neuraminidase to Sialic Acid by Reiter-Scherer, Valentin, Cuellar-Camacho, Jose Luis, Bhatia, Sumati, Haag, Rainer, Herrmann, Andreas, Lauster, Daniel, Rabe, Jürgen P.

“…The influenza A virus infects target cells through multivalent interactions of its major spike proteins, hemagglutinin (HA) and neuraminidase (NA), with the…”
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Exploring Rigid and Flexible Core Trivalent Sialosides for Influenza Virus Inhibition by Kiran, Pallavi, Bhatia, Sumati, Lauster, Daniel, Aleksić, Stevan, Fleck, Carsten, Peric, Natalija, Maison, Wolfgang, Liese, Susanne, Keller, Bettina G., Herrmann, Andreas, Haag, Rainer

“…Herein, the chemical synthesis and binding analysis of functionalizable rigid and flexible core trivalent sialosides bearing oligoethylene glycol (OEG) spacers…”
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Force Spectroscopy Shows Dynamic Binding of Influenza Hemagglutinin and Neuraminidase to Sialic Acid by Reiter-Scherer, Valentin, Cuellar-Camacho, Jose Luis, Bhatia, Sumati, Haag, Rainer, Herrmann, Andreas, Lauster, Daniel, Rabe, Jürgen P.

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Biocatalytic Route to Sugar-PEG-Based Polymers for Drug Delivery Applications by Bhatia, Sumati, Mohr, Andreas, Mathur, Divya, Parmar, Virinder S, Haag, Rainer, Prasad, Ashok K

“…Sugar-PEG-based polymers were synthesized by enzymatic copolymerization of…”
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Lipase-mediated synthesis of sugar–PEG-based amphiphiles for encapsulation and stabilization of indocyanine green by Khatri, Vinod, Bhatia, Sumati, Achazi, Katharina, Deep, Satyanarayan, Kohli, Ekta, Sharma, Sunil K., Haag, Rainer, Prasad, Ashok K.

“…Indocyanine green (ICG) is a near-infrared dye for wide-ranging applications, but its utility for biological studies is limited due to poor aqueous stability…”
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Exploring monovalent and multivalent peptides for the inhibition of FBP21-tWW by Henning, Lisa Maria, Bhatia, Sumati, Bertazzon, Miriam, Marczynke, Michaela, Seitz, Oliver, Volkmer, Rudolf, Haag, Rainer, Freund, Christian

“…The coupling of peptides to polyglycerol carriers represents an important route towards the multivalent display of protein ligands. In particular, the…”
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Potential of acylated peptides to target the influenza A virus by Lauster, Daniel, Pawolski, Damian, Storm, Julian, Ludwig, Kai, Volkmer, Rudolf, Memczak, Henry, Herrmann, Andreas, Bhatia, Sumati

“…For antiviral drug design, especially in the field of influenza virus research, potent multivalent inhibitors raise high expectations for combating epidemics…”
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Inhibition of Herpes Simplex Virus Type 1 Attachment and Infection by Sulfated Polyglycerols with Different Architectures by Pouyan, Paria, Nie, Chuanxiong, Bhatia, Sumati, Wedepohl, Stefanie, Achazi, Katharina, Osterrieder, Nikolaus, Haag, Rainer

“…Inhibition of herpes simplex virus type 1 (HSV-1) binding to the host cell surface by highly sulfated architectures is among the promising strategies to…”
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Dual tumor- and subcellular-targeted photodynamic therapy using glucose-functionalized MoS2 nanoflakes for multidrug-resistant tumor ablation by Xu, Shaohui, Zhang, Pan, Heing-Becker, Isabelle, Zhang, Junmei, Tang, Peng, Bej, Raju, Bhatia, Sumati, Zhong, Yinan, Haag, Rainer

“…Photodynamic therapy (PDT) is emerging as an efficient strategy to combat multidrug-resistant (MDR) cancer. However, the short half-life and limited diffusion…”
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Thermoresponsive Hydrogels as Microniches for Growth and Controlled Release of Induced Pluripotent Stem Cells by Liang, Wanjun, Bhatia, Sumati, Reisbeck, Felix, Zhong, Yinan, Singh, Abhishek Kumar, Li, Wenzhong, Haag, Rainer

“…The recently emerging stem‐cell artificial niche engineering in induced pluripotent stem cell (iPSCs) 3D cultures has provided enormous opportunities to fully…”
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Topology‐Matching Design of an Influenza‐Neutralizing Spiky Nanoparticle‐Based Inhibitor with a Dual Mode of Action by Nie, Chuanxiong, Parshad, Badri, Bhatia, Sumati, Cheng, Chong, Stadtmüller, Marlena, Oehrl, Alexander, Kerkhoff, Yannic, Wolff, Thorsten, Haag, Rainer

“…In this study, we demonstrate the concept of “topology‐matching design” for virus inhibitors. With the current knowledge of influenza A virus (IAV), we…”
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Design, Synthesis, and Biomedical Applications of Glycotripods for Targeting Trimeric Lectins by Khatri, Vinod, Parshad, Badri, Prasad, Ashok K., Bhatia, Sumati

“…In the last decades, various efforts have been made to synthesize optimal glycotripods for targeting trimeric glycoproteins like asialoglycoprotein receptor,…”
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Synthesis and Comparison of Linear Polymannosides for Direct Binding with Escherichia coli by Hanheiser, Natalie, Parshad, Badri, Povolotsky, Tatyana L., Khatri, Vinod, Achazi, Katharina, Bhatia, Sumati

“…Here, the synthesis of linear polyglycerols bearing multiple copies of mono and dimannosides (LPG40Man0.60 and LPG40(Manα1,2Man)0.60) is demonstrated. A method…”
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Correction to “Inhibition of Herpes Simplex Virus Type 1 Attachment and Infection by Sulfated Polyglycerols with Different Architectures” by Pouyan, Paria, Nie, Chuanxiong, Bhatia, Sumati, Wedepohl, Stefanie, Achazi, Katharina, Osterrieder, Nikolaus, Haag, Rainer

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Adaptive Flexible Sialylated Nanogels as Highly Potent Influenza A Virus Inhibitors by Bhatia, Sumati, Hilsch, Malte, Cuellar‐Camacho, Jose Luis, Ludwig, Kai, Nie, Chuanxiong, Parshad, Badri, Wallert, Matthias, Block, Stephan, Lauster, Daniel, Böttcher, Christoph, Herrmann, Andreas, Haag, Rainer

“…Flexible multivalent 3D nanosystems that can deform and adapt onto the virus surface via specific ligand–receptor multivalent interactions can efficiently…”
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Scaffold Flexibility Controls Binding of Herpes Simplex Virus Type 1 with Sulfated Dendritic Polyglycerol Hydrogels Fabricated by Thiol‐Maleimide Click Reaction by Thongrom, Boonya, Sharma, Antara, Nie, Chuanxiong, Quaas, Elisa, Raue, Marwin, Bhatia, Sumati, Haag, Rainer

“…Herpes Simplex Virus‐1 (HSV‐1) with a diameter of 155–240 nm uses electrostatic interactions to bind with the heparan sulfate present on the cell surface to…”
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Non-ionic small amphiphile based nanostructures for biomedical applications by Parshad, Badri, Prasad, Suchita, Bhatia, Sumati, Mittal, Ayushi, Pan, Yuanwei, Mishra, Prashant Kumar, Sharma, Sunil K, Fruk, Ljiljana

“…Self-assembly of non-ionic amphiphilic architectures into nanostructures with defined size, shape and morphology has garnered substantial momentum in the…”
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