Search Results - "Bhatia, Ravi"
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1
Stem Cell Quiescence
Published in Clinical cancer research (01-08-2011)“…Adult stem cells are maintained in a quiescent state but are able to exit quiescence and rapidly expand and differentiate in response to stress. The quiescent…”
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2
Monsoons: The Season of Good Health and Cheer
Published in Indian Pediatrics Case Reports (01-07-2023)Get full text
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3
An overview on advancements in biobased transesterification methods for biodiesel production: Oil resources, extraction, biocatalysts, and process intensification technologies
Published in Fuel (Guildford) (01-02-2021)“…[Display omitted] •Biodiesel is a renewable and ecofriendly biofuel.•It can be produced using transesterification, emulsification and pyrolysis process…”
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4
Trends in renewable energy production employing biomass-based biochar
Published in Bioresource technology (01-11-2021)“…[Display omitted] •Renewable energy seems a promising approach to fulfill the future energy demand.•Biochar is an economic, and efficient material for energy…”
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5
My Memorable Patient
Published in Indian Pediatrics Case Reports (01-10-2021)Get full text
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6
Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells
Published in Cell stem cell (02-05-2019)“…Chronic myeloid leukemia (CML) originates in a hematopoietic stem cell (HSC) transformed by the breakpoint cluster region (BCR)-abelson (ABL) oncogene and is…”
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7
Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths
Published in Cell reports (Cambridge) (09-07-2019)“…The bone marrow microenvironment is composed of heterogeneous cell populations of non-hematopoietic cells with complex phenotypes and undefined trajectories of…”
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8
High Frequency and Poor Outcome of Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia in Adults
Published in Journal of clinical oncology (01-02-2017)“…Purpose Philadelphia chromosome (Ph) -like acute lymphoblastic leukemia (ALL) is a high-risk subtype of childhood ALL characterized by kinase-activating…”
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Advances in algal biomass pretreatment and its valorisation into biochemical and bioenergy by the microbial processes
Published in Bioresource technology (01-08-2022)“…[Display omitted] •Algae can capture carbon dioxide and produce many valuable compounds.•Residual algal biomass is rich in various polysaccharides.•Biomass…”
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Altered Microenvironmental Regulation of Leukemic and Normal Stem Cells in Chronic Myelogenous Leukemia
Published in Cancer cell (17-04-2012)“…We characterized leukemia stem cells (LSC) in chronic phase chronic myelogenous leukemia (CML) using a transgenic mouse model. LSC were restricted to cells…”
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11
Osteoblast ablation reduces normal long-term hematopoietic stem cell self-renewal but accelerates leukemia development
Published in Blood (23-04-2015)“…Hematopoietic stem cells (HSCs) reside in regulatory niches in the bone marrow (BM). Although HSC niches have been extensively characterized, the role of…”
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Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor–treated CML stem cells
Published in Blood (08-12-2016)“…Treatment of chronic myelogenous leukemia (CML) with BCR-ABL tyrosine kinase inhibitors (TKI) fails to eliminate leukemia stem cells (LSC). Patients remain at…”
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13
Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis
Published in Blood (23-02-2012)“…The tyrosine kinase inhibitor imatinib is highly effective in the treatment of chronic myelogenous leukemia (CML), but primary and acquired resistance of CML…”
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14
Synthesis, properties and potential applications of two-dimensional transition metal dichalcogenides
Published in Nano Convergence (01-09-2015)“…In recent years, 2-dimensional (2D) materials such as graphene and h-BN have been spotlighted, because of their unique properties and high potential…”
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MicroRNA-486 regulates normal erythropoiesis and enhances growth and modulates drug response in CML progenitors
Published in Blood (19-02-2015)“…MicroRNAs (miRNAs) are key regulators of hematopoietic cell differentiation and may contribute to altered growth of leukemic stem cells. Using microarray-based…”
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Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia
Published in Nature medicine (01-04-2018)“…In chronic myelogenous leukemia, leukemia stem cell function requires a microRNA that is provided by bone marrow endothelial cells. Leukemia stem cells (LSCs)…”
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In Vitro Pre-Clinical Validation of Suicide Gene Modified Anti-CD33 Redirected Chimeric Antigen Receptor T-Cells for Acute Myeloid Leukemia
Published in PloS one (01-12-2016)“…Approximately fifty percent of patients with acute myeloid leukemia can be cured with current therapeutic strategies which include, standard dose chemotherapy…”
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18
miR-328 Functions as an RNA Decoy to Modulate hnRNP E2 Regulation of mRNA Translation in Leukemic Blasts
Published in Cell (05-03-2010)“…MicroRNAs and heterogeneous ribonucleoproteins (hnRNPs) are posttranscriptional gene regulators that bind mRNA in a sequence-specific manner. Here, we report…”
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SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function
Published in Cell stem cell (06-09-2018)“…Myelodysplastic syndrome (MDS), a largely incurable hematological malignancy, is derived from aberrant clonal hematopoietic stem/progenitor cells (HSPCs) that…”
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Role of altered growth factor receptor-mediated JAK2 signaling in growth and maintenance of human acute myeloid leukemia stem cells
Published in Blood (01-05-2014)“…Acute myeloid leukemia (AML) is sustained by small populations of leukemia stem cells (LSCs) that can resist available treatments and represent important…”
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