Search Results - "Bhatia, Harsharan S"

Refine Results
  1. 1
  2. 2

    Anti-neuroinflammatory effects of Ginkgo biloba extract EGb761 in LPS-activated primary microglial cells by Gargouri, Brahim, Carstensen, Johanna, Bhatia, Harsharan S., Huell, Michael, Dietz, Gunnar P.H., Fiebich, Bernd L.

    Published in Phytomedicine (Stuttgart) (15-05-2018)
    “…Neuroinflammation is a key factor of Alzheimer's disease (AD) and other neurodegenerative conditions. Microglia are the resident mononuclear immune cells of…”
    Get full text
    Journal Article
  3. 3

    Alleviation of Microglial Activation Induced by p38 MAPK/MK2/PGE2 Axis by Capsaicin: Potential Involvement of other than TRPV1 Mechanism/s by Bhatia, Harsharan S., Roelofs, Nora, Muñoz, Eduardo, Fiebich, Bernd L.

    Published in Scientific reports (08-03-2017)
    “…Exaggerated inflammatory responses in microglia represent one of the major risk factors for various central nervous system’s (CNS) associated pathologies…”
    Get full text
    Journal Article
  4. 4

    Resveratrol potently reduces prostaglandin E2 production and free radical formation in lipopolysaccharide-activated primary rat microglia by Candelario-Jalil, Eduardo, de Oliveira, Antonio C Pinheiro, Gräf, Sybille, Bhatia, Harsharan S, Hüll, Michael, Muñoz, Eduardo, Fiebich, Bernd L

    Published in Journal of neuroinflammation (10-10-2007)
    “…Neuroinflammatory responses are triggered by diverse ethiologies and can provide either beneficial or harmful results. Microglial cells are the major cell type…”
    Get full text
    Journal Article
  5. 5

    Pharmacological inhibition of Akt and downstream pathways modulates the expression of COX-2 and mPGES-1 in activated microglia by de Oliveira, Antonio C P, Candelario-Jalil, Eduardo, Langbein, Julia, Wendeburg, Lena, Bhatia, Harsharan S, Schlachetzki, Johannes C M, Biber, Knut, Fiebich, Bernd L

    Published in Journal of neuroinflammation (03-01-2012)
    “…Microglia are considered a major target for modulating neuroinflammatory and neurodegenerative disease processes. Upon activation, microglia secrete…”
    Get full text
    Journal Article
  6. 6

    Regulation of prostaglandin E2 synthase expression in activated primary rat microglia: Evidence for uncoupled regulation of mPGES-1 and COX-2 by de Oliveira, Antonio Carlos Pinheiro, Candelario-Jalil, Eduardo, Bhatia, Harsharan S., Lieb, Klaus, Hüll, Michael, Fiebich, Bernd L.

    Published in Glia (01-06-2008)
    “…Prostaglandin E2 (PGE2) is among the most important mediators involved in neuroinflammatory processes. The final step of its synthesis is regulated by enzymes…”
    Get full text
    Journal Article
  7. 7

    The anti-inflammatory effects of the 5-HT3 receptor antagonist tropisetron are mediated by the inhibition of p38 MAPK activation in primary human monocytes by Stratz, Christian, Bhatia, Harsharan S., Akundi, Ravi Shankar, Nührenberg, Thomas, Trenk, Dietmar, Muñoz, Eduardo, Fiebich, Bernd L.

    Published in International immunopharmacology (01-08-2012)
    “…There is evidence from human and animal research that 5-hydroxytryptamine (5-HT) 3 receptor antagonists, particularly tropisetron, exert analgesic and…”
    Get full text
    Journal Article
  8. 8

    Effects of diet and/or exercise in enhancing spinal cord sensorimotor learning by Joseph, M Selvan, Ying, Zhe, Zhuang, Yumei, Zhong, Hui, Wu, Aiguo, Bhatia, Harsharan S, Cruz, Rusvelda, Tillakaratne, Niranjala J K, Roy, Roland R, Edgerton, V Reggie, Gomez-Pinilla, Fernando

    Published in PloS one (20-07-2012)
    “…Given that the spinal cord is capable of learning sensorimotor tasks and that dietary interventions can influence learning involving supraspinal centers, we…”
    Get full text
    Journal Article
  9. 9

    Inflammatory and oxidative mechanisms potentiate bifenthrin-induced neurological alterations and anxiety-like behavior in adult rats by Gargouri, Brahim, Bhatia, Harsharan S., Bouchard, Michèle, Fiebich, Bernd L., Fetoui, Hamadi

    Published in Toxicology letters (15-09-2018)
    “…Graphical abstract summarizing the neurological alterations induced by BF. BF induces oxidative stress mediated inflammatory responses via the activation of…”
    Get full text
    Journal Article
  10. 10

    Inhibition of neuroinflammation by thymoquinone requires activation of Nrf2/ARE signalling by Velagapudi, Ravikanth, Kumar, Asit, Bhatia, Harsharan S., El-Bakoush, Abdelmeneim, Lepiarz, Izabela, Fiebich, Bernd L., Olajide, Olumayokun A.

    Published in International immunopharmacology (01-07-2017)
    “…Thymoquinone is an antioxidant phytochemical that has been shown to inhibit neuroinflammation. However, little is known about the potential roles of…”
    Get full text
    Journal Article
  11. 11
  12. 12

    Resveratrol inhibits prostaglandin formation in IL-1β-stimulated SK-N-SH neuronal cells by Wendeburg, Lena, de Oliveira, Antonio Carlos Pinheiro, Bhatia, Harsharan S, Candelario-Jalil, Eduardo, Fiebich, Bernd L

    Published in Journal of neuroinflammation (14-09-2009)
    “…Resveratrol, a polyphenol present in grapes and red wine, has been studied due to its vast pharmacological activity. It has been demonstrated that resveratrol…”
    Get full text
    Journal Article
  13. 13

    Rice bran derivatives alleviate microglia activation: possible involvement of MAPK pathway by Bhatia, Harsharan S, Baron, Julian, Hagl, Stephanie, Eckert, Gunter P, Fiebich, Bernd L

    Published in Journal of neuroinflammation (14-06-2016)
    “…Hyperactivation of microglia is considered to be a key hallmark of brain inflammation and plays a critical role in regulating neuroinflammatory events…”
    Get full text
    Journal Article
  14. 14

    Silica Nanoparticles Induce Hepatotoxicity by Triggering Oxidative Damage, Apoptosis, and Bax-Bcl2 Signaling Pathway by Aouey, Bakhta, Boukholda, Khadija, Gargouri, Brahim, Bhatia, Harsharan S., Attaai, Abdelraheim, Kebieche, Mohamed, Bouchard, Michèle, Fetoui, Hamadi

    Published in Biological trace element research (01-04-2022)
    “…The increase in the usage of silica nanoparticles (SiNPs) in the industrial and medical fields has raised concerns about their possible adverse effects on…”
    Get full text
    Journal Article
  15. 15

    Anti-neuroinflammatory properties of synthetic cryptolepine in human neuroblastoma cells: Possible involvement of NF-κB and p38 MAPK inhibition by Olajide, Olumayokun A., Bhatia, Harsharan S., de Oliveira, Antonio C.P., Wright, Colin W., Fiebich, Bernd L.

    Published in European journal of medicinal chemistry (01-05-2013)
    “…Cryptolepis sanguinolenta and its bioactive alkaloid, cryptolepine have shown anti-inflammatory activity. However, the underlying mechanism of…”
    Get full text
    Journal Article
  16. 16

    Mangiferin inhibits cyclooxygenase-2 expression and prostaglandin E2 production in activated rat microglial cells by Bhatia, Harsharan S, Candelario-Jalil, Eduardo, de Oliveira, Antonio C Pinheiro, Olajide, Olumayokun A, Martínez-Sánchez, Gregorio, Fiebich, Bernd L

    Published in Archives of biochemistry and biophysics (15-09-2008)
    “…Mangiferin, a naturally occurring glucosylxanthone, has potent antioxidant and anti-inflammatory properties, as demonstrated in several reports. However, very…”
    Get full text
    Journal Article
  17. 17

    Inhibition of Neuroinflammation in LPS-Activated Microglia by Cryptolepine by Olajide, Olumayokun A., Bhatia, Harsharan S., de Oliveira, Antonio C. P., Wright, Colin W., Fiebich, Bernd L.

    “…Cryptolepine, an indoloquinoline alkaloid in Cryptolepis sanguinolenta, has anti-inflammatory property. In this study, we aimed to evaluate the effects of…”
    Get full text
    Journal Article
  18. 18

    The anti-inflammatory effects of the 5-HT3 receptor antagonist tropisetron are mediated by the inhibition of p38 MAPK activation in primary human monocytes by Stratz, Christian, Bhatia, Harsharan S, Akundi, Ravi Shankar, Nührenberg, Thomas, Trenk, Dietmar, Muñoz, Eduardo, Fiebich, Bernd L

    Published in Brain, behavior, and immunity (15-02-2013)
    “…There is evidence from human and animal research that 5-hydroxytryptamine (5-HT) 3 receptor antagonists, particularly tropisetron, exert analgesic and…”
    Get full text
    Journal Article
  19. 19

    Ascorbic acid enhances the inhibitory effect of aspirin on neuronal cyclooxygenase-2-mediated prostaglandin E2 production by Candelario-Jalil, Eduardo, Akundi, Ravi S, Bhatia, Harsharan S, Lieb, Klaus, Appel, Kurt, Muñoz, Eduardo, Hüll, Michael, Fiebich, Bernd L

    Published in Journal of neuroimmunology (01-05-2006)
    “…Inhibition of neuronal cyclooxygenase-2 (COX-2) and hence prostaglandin E2 (PGE2) synthesis by non-steroidal anti-inflammatory drugs has been suggested to…”
    Get full text
    Journal Article
  20. 20