Search Results - "Bhatia, Ashima"

Plasma and Intrapulmonary Concentrations of Cefepime and Zidebactam following Intravenous Administration of WCK 5222 to Healthy Adult Subjects by Rodvold, Keith A, Gotfried, Mark H, Chugh, Rakesh, Gupta, Mugdha, Patel, Anasuya, Chavan, Rajesh, Yeole, Ravindra, Friedland, H David, Bhatia, Ashima

“…WCK 5222 is a combination of cefepime and the novel β-lactam enhancer zidebactam being developed for the treatment of serious Gram-negative bacterial…”
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Single-Center Investigation of the Pharmacokinetics of WCK 4282 (Cefepime-Tazobactam Combination) in Renal Impairment by Preston, Richard A, Mamikonyan, Grigor, Mastim, Mushtaque, Garg, Dyal, Kemper, Christopher J, Xu, Allan, Yeole, Ravindra, Chavan, Rajesh, Friedland, H David, Bhatia, Ashima

“…WCK 4282 is a combination product of cefepime (FEP) and tazobactam (TAZ) in a 1:1 ratio currently under development for the treatment of multidrug-resistant…”
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Electrocardiographic Effects of a Supratherapeutic Dose of WCK 2349, a Benzoquinolizine Fluoroquinolone by Mason, Jay W., Chugh, Rakesh, Patel, Anasuya, Gutte, Ranjeet, Bhatia, Ashima

“…The purpose of this study was to measure the electrocardiographic (ECG) effects of WCK 2349 (the L‐alanine ester prodrug of levonadifloxacin) at a…”
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Correction to: Comparative evaluation of pharmacokinetics and pharmacodynamics of insulin glargine (Glaritus®) and Lantus® in healthy subjects: a double-blind, randomized clamp study by Bhatia, Ashima, Tawade, Shraddha, Mastim, Mushtaque, Kitabi, Eliford Ngaimisi, Gopalakrishnan, Mathangi, Shah, Manish, Yeshamaina, Sridhar, Gobburu, Joga, Sahib, Maharaj, Thakur, Dipak, Prasanna Kumar, K. M.

“…Authors would like to correct the error in table 2 of the online published article…”
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A Prospective Multicenter Study to Evaluate the Safety and Efficacy of the Topical Application of MYOWNN™, an Autologous Growth Factor Concentrate (AGFC) Serum, in Anti-Aging by Chandrashekar, B. S., Sarangi, Kalpana, Mastim, Mushtaque A, Bhatia, Ashima, Shah, Manishkumar, Sharma, Vijay, Gupta, Mugdha, Gutte, Ranjeet, Sharma, Anuka, Sakhalkar, Ulka

“…BackgroundGrowth factors from platelets have been emerging as a revolutionary treatment with the ability to induce cell growth in the skin, which results in…”
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An Open-Labeled Randomized Prospective Multi-center Study to Evaluate the Efficacy and Safety of Intra-articular Injection of OSSINEXT™, an Autologous Growth Factor Concentrate (AGFC) Compared to Hyaluronic Acid (HA) in Knee Osteoarthritis by Mastim, Mushtaque A, Borana, Chirag, Shah, Vrajesh, Dhadiwal, Rajesh, Malhotra, Ravi, Kidiyoor, Brijesh, Kale, Amit, Gupta, Mugdha, Shah, Manishkumar D, Gutte, Ranjeet, Sharma, Anuka, Sharma, Vijay, Bhatia, Ashima

“…Osteoarthritis (OA) is known as degenerative arthritis and is the second most common rheumatologic problem with a prevalence of 22%-39% in India. Knee OA (KOA)…”
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Role of p-glycoprotein expression in predicting response to neoadjuvant chemotherapy in breast cancer--a prospective clinical study by Chintamani, Singh, Jai Parakash, Mittal, Mahesh K, Saxena, Sunita, Bansal, Anju, Bhatia, Ashima, Kulshreshtha, Pranjal

“…Neoadjuvant chemotherapy (NACT) is an integral part of multi-modality approach in the management of locally advanced breast cancer. It is vital to predict…”
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Playing Hide-and-Seek with Tyrosine Kinase Inhibitors: Can We Overcome Administration Challenges? by Kollipara, Sivacharan, Chougule, Mahendra, Boddu, Rajkumar, Bhatia, Ashima, Ahmed, Tausif

“…Tyrosine kinase inhibitors (TKIs) have demonstrated significant efficacy against various types of cancers through molecular targeting mechanisms. Over the past…”
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Biopredictive Dissolutions for Conventional Oral IR, MR and Non-Oral Formulations – Current Status and Future Opportunities by Mondal, Smritilekha, Kollipara, Sivacharan, Chougule, Mahendra, Bhatia, Ashima, Ahmed, Tausif

“…Over the past few decades, biopredictive dissolution coupled with physiologically based biopharmaceutics modeling (PBBM) has gained significance due to its…”
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Automation of human behaviors and its prediction using machine learning by Jupalle, Hruthika, Kouser, Shama, Bhatia, Ashima Bhatnagar, Alam, Naved, Nadikattu, Rahul Reddy, Whig, Pawan

“…Prediction is a method of detecting a person's behavior toward online buying by evaluating publically available evaluations on the web. Understanding…”
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Safety, tolerability and pharmacokinetics of oral nafithromycin (WCK4873) after single or multiple doses and effects of food on single-dose bioavailability in healthy adult subjects by Iwanowski, Piotr, Bhatia, Ashima, Gupta, Mugdha, Patel, Anasuya, Chavan, Rajesh, Yeole, Ravindra, Friedland, David

“…Nafithromycin (WCK 4873), a novel lactone-ketolide, was administered to healthy adult subjects in 2 randomized, double-blind, placebo-controlled, Phase 1…”
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Dissolution Profiles Comparison Using Conventional and Bias Corrected and Accelerated f2 Bootstrap Approaches with Different Software’s: Impact of Variability, Sample Size and Number of Bootstraps by Boddu, Rajkumar, Kollipara, Sivacharan, Bhattiprolu, Adithya Karthik, Parsa, Karthik, Chakilam, Sanketh Kumar, Daka, Krishna Reddy, Bhatia, Ashima, Ahmed, Tausif

“…Dissolution profiles comparison is an important element in order to support biowaivers, scale-up and post approval changes and site transfers. Highly variable…”
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Intrapulmonary Pharmacokinetics of Levonadifloxacin following Oral Administration of Alalevonadifloxacin to Healthy Adult Subjects by Rodvold, Keith A, Gotfried, Mark H, Chugh, Rakesh, Gupta, Mugdha, Yeole, Ravindra, Patel, Anasuya, Bhatia, Ashima

“…Alalevonadifloxacin (WCK 2349) is a novel l-alanine ester prodrug of levonadifloxacin that is being developed as an oral fluoroquinolone antibiotic. The…”
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Safety, Tolerability, and Pharmacokinetics of Oral Nafithromycin (WCK 4873) after Single or Multiple Doses and Effects of Food on Single-Dose Bioavailability in Healthy Adult Subjects by Iwanowski, Piotr, Bhatia, Ashima, Gupta, Mugdha, Patel, Anasuya, Chavan, Rajesh, Yeole, Ravindra, Friedland, David

“…Nafithromycin (WCK 4873), a novel lactone-ketolide, was administered to healthy adult subjects in 2 randomized, double-blind, placebo-controlled, phase 1…”
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Single-Center Evaluation of the Pharmacokinetics of WCK 5222 (Cefepime-Zidebactam Combination) in Subjects with Renal Impairment by Preston, Richard A, Mamikonyan, Grigor, DeGraff, Stephane, Chiou, James, Kemper, Christopher J, Xu, Allan, Mastim, Mushtaque, Yeole, Ravindra, Chavan, Rajesh, Patel, Anasuya, Friedland, H David, Bhatia, Ashima

“…WCK 5222 is a novel β-lactam-β-lactam-enhancer combination of cefepime (FEP) and zidebactam (ZID). ZID is a novel β-lactam enhancer with a dual action of…”
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Comparison of Plasma and Intrapulmonary Concentrations of Nafithromycin (WCK 4873) in Healthy Adult Subjects by Rodvold, Keith A, Gotfried, Mark H, Chugh, Rakesh, Gupta, Mugdha, Friedland, H David, Bhatia, Ashima

“…The nafithromycin concentrations in the plasma, epithelial lining fluid (ELF), and alveolar macrophages (AM) of 37 healthy adult subjects were measured…”
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Levonadifloxacin, a Novel Broad-Spectrum Anti-MRSA Benzoquinolizine Quinolone Agent: Review of Current Evidence by Bhagwat, Sachin S, Nandanwar, Manohar, Kansagara, Atul, Patel, Anusuya, Takalkar, Swapna, Chavan, Rajesh, Periasamy, Hariharan, Yeole, Ravindra, Deshpande, Prasad K, Bhavsar, Satish, Bhatia, Ashima, Ahdal, Jaishid, Jain, Rishi, Patel, Mahesh

“…Levonadifloxacin and its prodrug alalevonadifloxacin are novel broad-spectrum anti-MRSA agents belonging to the benzoquinolizine subclass of quinolone,…”
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Zidebactam Phase 1 Single Ascending Dose and Crossover Study in Healthy Subjects by Bhatia, Ashima, Gupta, Mugdha, Chugh, Rakesh

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Comparative evaluation of pharmacokinetics and pharmacodynamics of insulin glargine (Glaritus®) and Lantus® in healthy subjects: a double-blind, randomized clamp study by Bhatia, Ashima, Tawade, Shraddha, Mastim, Mushtaque, Kitabi, Eliford Ngaimisi, Gopalakrishnan, Mathangi, Shah, Manish, Yeshamaina, Sridhar, Gobburu, Joga, Sahib, Maharaj, Thakur, Dipak, Prasanna Kumar, K. M.

“…Aims The objective of the study was to compare the pharmacokinetic (PK) and pharmacodynamic (PD) properties of an insulin glargine formulation, Glaritus ®…”
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Topical phenytoin for wound healing by Bhatia, Ashima, Prakash, Surya

“…Oral phenytoin is used widely for the treatment of convulsive disorders and about half the patients treated develop gingival overgrowth as a side effect. The…”
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