Search Results - "Bhatia, Alka"
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Multiple Platelet-Rich Plasma Injections Versus Single Platelet-Rich Plasma Injection in Early Osteoarthritis of the Knee: An Experimental Study in a Guinea Pig Model of Early Knee Osteoarthritis
Published in The American journal of sports medicine (01-08-2019)“…Background: Platelet-rich plasma (PRP) has emerged as the forerunner among disease-modifying treatment options for early osteoarthritis (OA) of the knee…”
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Butyrate induced Tregs are capable of migration from the GALT to the pancreas to restore immunological tolerance during type-1 diabetes
Published in Scientific reports (05-11-2020)“…Type-1 diabetes (T1D) is an autoimmune disease caused by progressive loss of insulin-producing beta cells in the pancreas. Butyrate is a commensal…”
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Catecholamines’ accumulation and their disturbed metabolism at perilesional site: a possible cause of vitiligo progression
Published in Archives of dermatological research (01-03-2023)“…Catecholamines (epinephrine, norepinephrine and dopamine) are considered toxic to the melanocytes and may play an important role in the development of…”
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Cancer cell micronucleus: an update on clinical and diagnostic applications
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01-07-2013)“…Micronucleus (MN) is the small nucleus that forms whenever a chromosome or its fragment is not incorporated into one of the daughter nuclei during cell…”
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High prevalence of chromosome 17 in breast cancer micronuclei: a means to get rid of tumor suppressors?
Published in Human cell : official journal of Human Cell Research Society (22-10-2024)“…Micronuclei (MN), defined as small extra-nuclear chromatin bodies enclosed by a nuclear envelope, serve as noticeable markers of chromosomal instability (CIN)…”
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Assessment of pathogenic potential of Acanthamoeba isolates by in vitro and in vivo tests
Published in Parasitology research (1987) (01-09-2023)“…Acanthamoeba are free-living protozoa present ubiquitously in numerous environmental reservoirs that exist as an actively feeding trophozoite or a dormant cyst…”
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Role of IL‐17A receptor blocking in melanocyte survival: A strategic intervention against vitiligo
Published in Experimental dermatology (01-06-2019)“…Cytokines regulate immune response and inflammation and play an important role in depigmentation process of an autoimmune disease, vitiligo. We sought to…”
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Evaluation of the effect of probiotic as add-on therapy with conventional therapy and alone in malaria induced mice
Published in BMC research notes (30-06-2021)“…Chloroquine is used as a conventional drug therapy for the treatment of malaria. The existence of resistance to chloroquine shown among various species of…”
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Cancer stem cell, chromosomal instability, and cancer immunity
Published in Exploration of immunology (02-04-2024)“…Cancer stem cells (CSCs) are a unique population of tumor cells with stem cell-like properties. They are believed to be involved in drug resistance, potential…”
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Pharmacokinetic assessment of isoniazid and acetylisoniazid in carbon tetrachloride-induced liver injury model in Wistar rats
Published in Journal of pharmacy & bioallied science (01-07-2023)“…Background: N-acetyl transferase 2 (NAT2) polymorphism testing could not see the light of success as a biomarker tool in tuberculosis management. Additionally,…”
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Pharmacokinetic assessment of pyrazinamide and pyrazinoic acid in carbon tetrachloride-induced liver injury model in Wistar Rats
Published in Journal of pharmacy & bioallied science (01-07-2023)“…Background: We investigated the pharmacokinetic behavior of pyrazinamide (PZA) and pyrazinoic acid (PA) in the presence of carbon-tetrachloride (CCl4) plus…”
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Inhibition of the ERK1/2 Phosphorylation by Dextromethorphan Protects against Core Autistic Symptoms in VPA Induced Autistic Rats: In Silico and in Vivo Drug Repurposition Study
Published in ACS chemical neuroscience (19-05-2021)“…The imbalance between excitatory and inhibitory neurotransmitters is explicitly related to the pathophysiology of autism spectrum disorder (ASD). The role of…”
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Antinuclear antibodies and their detection methods in diagnosis of connective tissue diseases: a journey revisited
Published in Diagnostic pathology (02-01-2009)“…It has been more than 50 years since antinuclear antibodies were first discovered and found to be associated with connective tissue diseases. Since then…”
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Do Different Stemness Markers Identify Different Pools of Cancer Stem Cells in Malignancies: A Study on ER+ and ER-Breast Cancer Cell Lines
Published in Pathology oncology research (2020)“…In view of popularity of cancer stem cell (CSC) model all events in evolution of cancer are being explained in that context. Breast cancer is first solid tumor…”
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An Insight into the Genome of Pathogenic and Non-Pathogenic Acanthamoeba
Published in Pathogens (Basel) (19-12-2022)“…are amphizoic amoeba majorly responsible for causing keratitis (AK) and Granulomatous amoebic encephalitis (GAE). Despite its ubiquitous nature, the frequency…”
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Effect of dietary AGEs on the transcriptional profile of peripheral blood lymphocytes
Published in Applied Food Research (01-06-2022)“…•Cooking procedures involving exposure to high temperatures like frying and baking lead to the formation of toxins like AGEs.•Increased AGE specific…”
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TCF 4 tumor suppressor: a molecular target in the prognosis of sporadic colorectal cancer in humans
Published in Cellular & molecular biology letters (31-03-2020)“…A huge array of function is played by the Wnt/β-catenin signaling pathway in development by balancing gene expression through the modulation of cell-specific…”
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Vibrio Phage VMJ710 Can Prevent and Treat Disease Caused by Pathogenic MDR V. cholerae O1 in an Infant Mouse Model
Published in Antibiotics (Basel) (14-06-2023)“…Cholera, a disease of antiquity, is still festering in developing countries that lack safe drinking water and sewage disposal. , the causative agent of…”
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Doxycycline Promotes Carcinogenesis & Metastasis via Chronic Inflammatory Pathway: An In Vivo Approach
Published in PloS one (21-03-2016)“…Doxycycline (DOX) exhibits anti-inflammatory, anti-tumor, and pro-apoptotic activity and is being tested in clinical trials as a chemotherapeutic agent for…”
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Dose-Response Evaluation of Scopoletin, a Phytochemical, in a High-Fructose High-Fat Diet-Induced Dyslipidemia Model in Wistar Rats
Published in Journal of medicinal food (01-05-2023)“…The putative hypolipidemic properties of scopoletin have not been fully confirmed due to a lack of validation in an irreversible chronic hyperlipidemia animal…”
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