May-Thurner Syndrome

May-Thurner Syndrome

This single-center, retrospective review identified 6 patients (n = 6, 100% female) treated by endovascular therapy for May-Thurner syndrome from June 2013 to September 2015. Patients consisted of 3 African American, 2 Caucasian and 1 Asian; mean age was 53.50 ± 8.31 years, range: 39-63 years. Clini...

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Bibliographic Details
Published in:The American journal of the medical sciences Vol. 355; no. 5; pp. 510 - 514
Main Authors: Sedhai, Yub Raj, Golamari, Reshma, Salei, Aliaksei, Alukal, Joseph, Basnyat, Soney, Pathak, Sunil, Timalsina, Santosh, Zia, Subtain, Malhan, Suraj, Bhatacharya, Priyanka T.
Format: Journal Article
Language:English
Published: United States Elsevier Inc 01-05-2018
Copyright by the Southern Society for Clinical Investigation. Unauthorized reproduction of this article is prohibited
Subjects:
Adult
Angioplasty, Balloon
Catheterization, Peripheral
Deep vein thrombosis
Female
Humans
May-Thurner syndrome
May-Thurner Syndrome - complications
May-Thurner Syndrome - diagnostic imaging
May-Thurner Syndrome - therapy
Mechanical Thrombolysis
Middle Aged
Pharmaco-mechanical thrombolysis
Pulmonary Embolism - complications
Pulmonary Embolism - diagnostic imaging
Pulmonary Embolism - therapy
Pulmonary embolism and endovascular treatment
Retrospective Studies
Stents
Tomography, X-Ray Computed
Treatment Outcome
Ultrasonography, Doppler
Venous Thrombosis - complications
Venous Thrombosis - diagnostic imaging
Venous Thrombosis - therapy
Deep vein thrombosis
Pharmaco-mechanical thrombolysis
May-Thurner syndrome
Pulmonary embolism and endovascular treatment
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Summary:This single-center, retrospective review identified 6 patients (n = 6, 100% female) treated by endovascular therapy for May-Thurner syndrome from June 2013 to September 2015. Patients consisted of 3 African American, 2 Caucasian and 1 Asian; mean age was 53.50 ± 8.31 years, range: 39-63 years. Clinical presentations consisted of left lower extremity deep vein thrombosis in 4, left lower extremity deep vein thrombosis with pulmonary embolism in 1 and pulmonary embolism with left common iliac vein thrombosis in 1 patient. All 6 patients were treated with catheter‐directed thrombolysis and venous stenting to correct the underlying anatomical defect. Hypercoagulability work up revealed antiphospholipid antibody syndrome in 1 patient. No major periprocedural complications were observed. Median follow-up period was 22 ± 5.5 months (range: 13-30 months). One patient with pre-exiting antiphospholipid antibody syndrome developed stent thrombosis with secondary loss of patency. Endovascular therapy for May-Thurner syndrome in our adult cohort seemed safe and effective. One patient with pre-existing thrombophilia developed secondary loss of stent patency, suggesting need for further investigation in this subgroup.
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ISSN:0002-9629
1538-2990
DOI:10.1016/j.amjms.2017.09.011