Search Results - "Bhat, Tariq A"

Restoration of mitochondria function as a target for cancer therapy by Bhat, Tariq A., Kumar, Sandeep, Chaudhary, Ajay K., Yadav, Neelu, Chandra, Dhyan

“…•Mitochondria dysfunction is a key reason for therapy resistance in cancer.•Defective oxidative phosphorylation contributes to mitochondria dysfunction.•Heat…”
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Acute Effects of Heated Tobacco Product (IQOS) Aerosol Inhalation on Lung Tissue Damage and Inflammatory Changes in the Lungs by Bhat, Tariq A, Kalathil, Suresh G, Leigh, Noel, Muthumalage, Thivanka, Rahman, Irfan, Goniewicz, Maciej L, Thanavala, Yasmin M

“…Emerging heated tobacco products (HTPs) were designed to reduce exposure to toxicants from cigarette smoke (CS) by avoiding burning tobacco and instead heating…”
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Can switching from cigarettes to heated tobacco products reduce consequences of pulmonary infection? by Bhat, Tariq A, Kalathil, Suresh G, Leigh, Noel J, Goniewicz, Maciej L, Thanavala, Yasmin M

“…While tobacco industry data suggests that switching from combustible cigarettes to heated tobacco products (HTPs), like IQOS, may reduce the users' exposure to…”
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Do alternative tobacco products induce less adverse respiratory risk than cigarettes? by Bhat, Tariq A, Kalathil, Suresh G, Leigh, Noel, Hutson, Alan, Goniewicz, Maciej L, Thanavala, Yasmin M

“…Due to the relatively short existence of alternative tobacco products, gaps exist in our current understanding of their long-term respiratory health effects…”
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The Urinary Microbiome and Bladder Cancer by Heidar, Nassib Abou, Bhat, Tariq A, Shabir, Usma, Hussein, Ahmed A

“…Bladder cancer is the 10th most common cancer worldwide. Approximately 75% of patients with bladder cancer will present with non-muscle invasive disease…”
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Hypertensive phenotypes and pattern of ambulatory blood pressure in patients of diabetes mellitus of kashmir valley by Bhat, Tariq, Mir, Mohammad, Naqati, Shaariq, Naik, Muzafar, Naqash, Mubarik

“…Background: Patients of diabetes mellitus (DM) with hypertension (HTN) have a fourfold increased risk of cardiovascular disease (CVD) as compared to…”
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Immune Dysfunction in Patients with Chronic Obstructive Pulmonary Disease by Bhat, Tariq A, Panzica, Louis, Kalathil, Suresh Gopi, Thanavala, Yasmin

“…Chronic obstructive pulmonary disease (COPD) is a complex chronic disease. Chronic inflammation is the hallmark of COPD, involving the interplay of a wide…”
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An Animal Model of Inhaled Vitamin E Acetate and EVALI-like Lung Injury by Bhat, Tariq A, Kalathil, Suresh G, Bogner, Paul N, Blount, Benjamin C, Goniewicz, Maciej L, Thanavala, Yasmin M

“…In this study, investigators developed a mouse model of e-cigarette, or vaping, product use–associated lung injury. They showed that in these mice, vitamin E…”
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Not all vaping is the same: differential pulmonary effects of vaping cannabidiol versus nicotine by Bhat, Tariq A, Kalathil, Suresh G, Goniewicz, Maciej L, Hutson, Alan, Thanavala, Yasmin

“…Vaping has become a popular method of inhaling various psychoactive substances. While evaluating respiratory effects of vaping have primarily focused on…”
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Endoplasmic reticulum-mediated unfolded protein response and mitochondrial apoptosis in cancer by Bhat, Tariq A., Chaudhary, Ajay K., Kumar, Sandeep, O’Malley, Jordan, Inigo, Joseph R., Kumar, Rahul, Yadav, Neelu, Chandra, Dhyan

“…Abrogation of endoplasmic reticulum (ER) protein folding triggered by exogenous or endogenous factors, stimulates a cellular stress response, termed ER stress…”
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Specialized Proresolving Mediators Overcome Immune Suppression Induced by Exposure to Secondhand Smoke by Bhat, Tariq A, Kalathil, Suresh Gopi, Miller, Austin, Thatcher, Thomas H, Sime, Patricia J, Thanavala, Yasmin

“…Tobacco smoke exposure is associated with multiple diseases including, respiratory diseases like asthma and chronic obstructive pulmonary disease. Tobacco…”
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Decursin inhibits EGFR‐ERK1/2 signaling axis in advanced human prostate carcinoma cells by Bhat, Tariq A., Dheeraj, Arpit, Nambiar, Dhanya K., Singh, Surya Pratap, Yim, Dong Sool, Singh, Rana P.

“…We have shown that decursin, a coumarin compound, induces cell cycle arrest and apoptosis in human prostate cancer cells (PCa); however, its molecular…”
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A potential role of X-linked inhibitor of apoptosis protein in mitochondrial membrane permeabilization and its implication in cancer therapy by Chaudhary, Ajay K., Yadav, Neelu, Bhat, Tariq A., O’Malley, Jordan, Kumar, Sandeep, Chandra, Dhyan

“…•XIAP harbors prosurvival, proapoptotic and nonapoptotic functions.•Proapoptotic BH3-only protein Bim can regulate XIAP translocation to mitochondria.•XIAP…”
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AT-RvD1 Mitigates Secondhand Smoke-Exacerbated Pulmonary Inflammation and Restores Secondhand Smoke-Suppressed Antibacterial Immunity by Bhat, Tariq A, Kalathil, Suresh Gopi, Bogner, Paul N, Lehmann, Paul V, Thatcher, Thomas H, Sime, Patricia J, Thanavala, Yasmin

“…Cigarette smoke is a potent proinflammatory trigger contributing to acute lung injury and the development of chronic lung diseases via mechanisms that include…”
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Secondhand Smoke Induces Inflammation and Impairs Immunity to Respiratory Infections by Bhat, Tariq A, Kalathil, Suresh Gopi, Bogner, Paul N, Miller, Austin, Lehmann, Paul V, Thatcher, Thomas H, Phipps, Richard P, Sime, Patricia J, Thanavala, Yasmin

“…Despite advocacy to reduce smoking-related diseases, >1 billion people worldwide continue to smoke. Smoking is immunosuppressive and an important etiological…”
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Does the urinary microbiome profile change after treatment of bladder cancer? by Hussein, Ahmed A., Bhat, Tariq A., Jing, Zhe, Gomez, Eduardo Cortes, Wasay, Mahmood Abdul, Singh, Prashant K., Liu, Song, Smith, Gary, Guru, Khurshid A.

“…Introduction We sought to investigate the change in the urinary microbiome profile after transurethral resection of bladder tumor (TURBT). Methods Urine…”
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Acacetin Inhibits In Vitro and In Vivo Angiogenesis and Downregulates Stat Signaling and VEGF Expression by BHAT, Tariq A, NAMBIAR, Dhanya, TAILOR, Dhanir, PAL, Arttatrana, AGARWAL, Rajesh, SINGH, Rana P

“…Angiogenesis is an effective target in cancer control. The antiangiogenic efficacy and associated mechanisms of acacetin, a plant flavone, are poorly known. In…”
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Tumor angiogenesis – A potential target in cancer chemoprevention by Bhat, Tariq A., Singh, Rana P.

“…Tumor angiogenesis is critically important for the growth of solid tumors as tumors remain in dormant phase for a long time in the absence of the initiation of…”
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Cytochrome c Deficiency Confers Apoptosome and Mitochondrial Dysfunction in African-American Men with Prostate Cancer by Kumar, Rahul, Bhat, Tariq A, Walsh, Elise M, Chaudhary, Ajay K, O'Malley, Jordan, Rhim, Johng S, Wang, Jianmin, Morrison, Carl D, Attwood, Kristopher, Bshara, Wiam, Mohler, James L, Yadav, Neelu, Chandra, Dhyan

“…Although African-American (AA) patients with prostate cancer tend to develop greater therapeutic resistance and faster prostate cancer recurrence compared with…”
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Fisetin inhibits various attributes of angiogenesis in vitro and in vivo-implications for angioprevention by Bhat, Tariq A., Nambiar, Dhanya, Pal, Arttatrana, Agarwal, Rajesh, Singh, Rana P.

“…Studies have shown that fisetin, a small phytochemical molecule, has antitumor activity; however, its antiangiogenic activity has not yet been examined…”
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