Search Results - "Bhasin, Virendra K"

Potent antimalarial activity of newly synthesized substituted chalcone analogs in vitro by Awasthi, Satish K, Mishra, Nidhi, Kumar, Brajesh, Sharma, Manish, Bhattacharya, Amit, Mishra, Lokesh C, Bhasin, Virendra K

“…Several new chalcone analogues were synthesized and evaluated as inhibitors of malaria parasite. Inhibitory activity was determined in vitro against a…”
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Mutant pfcrt "SVMNT" haplotype and wild type pfmdr1 "N86" are endemic in Plasmodium vivax dominated areas of India under high chloroquine exposure by Mallick, Prashant K, Joshi, Hema, Valecha, Neena, Sharma, Surya K, Eapen, Alex, Bhatt, Rajendra M, Srivastava, Harish C, Sutton, Patrick L, Dash, Aditya P, Bhasin, Virendra K

“…Chloroquine resistance (CQR) phenotype in Plasmodium falciparum is associated with mutations in pfcrt and pfmdr-1 genes. Mutations at amino acid position 72-76…”
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Antimalarial Activity of Newly Synthesized Chalcone Derivatives In Vitro by Yadav, Neesha, Dixit, Sandeep K., Bhattacharya, Amit, Mishra, Lokesh C., Sharma, Manish, Awasthi, Satish K., Bhasin, Virendra K.

“…Twenty‐seven novel chalcone derivatives were synthesized using Claisen‐Schmidt condensation and their antimalarial activity against asexual blood stages of…”
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HIV Protease Inhibitors, Indinavir or Nelfinavir, Augment Antimalarial Action of Artemisinin in vitro by Mishra, Lokesh C, Bhattacharya, Amit, Sharma, Manish, Bhasin, Virendra K

“…Most malaria endemic regions are co-infested with HIV infection. Treatment of one may affect outcome of the other in co-infected individuals. HIV protease…”
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Synthesis of novel substituted 1,3-diaryl propenone derivatives and their antimalarial activity in vitro by Mishra, Nidhi, Arora, Preeti, Kumar, Brajesh, Mishra, Lokesh C., Bhattacharya, Amit, Awasthi, Satish K., Bhasin, Virendra K.

“…The synthesis of novel 1,3-diaryl propenone derivatives and their antimalarial activity in vitro against asexual blood stages of human malaria parasite,…”
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Antimalarial pharmacodynamics of chalcone derivatives in combination with artemisinin against Plasmodium falciparum in vitro by Bhattacharya, Amit, Mishra, Lokesh C., Sharma, Manish, Awasthi, Satish K., Bhasin, Virendra K.

“…Use of artemisinin based combination therapies (ACTs) is increasing in treatment of malaria. Their extensive and indiscriminate deployment will ultimately lead…”
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Problems with the oral polio vaccine by Bhasin, Virendra K

“…A letter to the editor suggests that the oral polio vaccine has outlived its utility; it is not providing herd immunity anymore. Children seem to be getting…”
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Short Report: HIV Protease Inhibitors, Indinavir or Nelfinavir, Augment Antimalarial Action of Artemisinin in vitro by MISHRA, Lokesh C, BHATTACHARYA, Amit, SHARMA, Manish, BHASIN, Virendra K

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Phytochemical licochalcone A enhances antimalarial activity of artemisinin in vitro by Mishra, Lokesh C., Bhattacharya, Amit, Bhasin, Virendra K.

“…Resistance to synthetic first-line antimalarial drugs is considered to be a major cause of increased malaria morbidity and mortality. Use of artemisinin-based…”
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In Vitro Activity of Artemisinin in Combination with Clotrimazole or Heat-treated Amphotericin B against Plasmodium falciparum by Bhattacharya, Amit, Mishra, Lokesh C, Bhasin, Virendra K

“…Currently available artemisinin-based combination therapies (ACTs) for malaria are inadequate. There remains an enormous unmet need for alternate…”
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Reduced heterozygosity at intragenic and flanking microsatellites of pfcrt gene establishes natural selection based molecular evolution of chloroquine-resistant Plasmodium falciparum in India by Mallick, Prashant K., Singh, Ruchi, Singh, Om P., Singh, Ashok K., Bhasin, Virendra K., Valecha, Neena

“…•New microsatellite markers identified in introns of pfcrt gene.•Reduced heterozygosity observed in intragenic microsatellite of pfcrt gene.•Confirmed…”
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Microsatellite analysis of chloroquine resistance associated alleles and neutral loci reveal genetic structure of Indian Plasmodium falciparum by Mallick, Prashant K., Sutton, Patrick L., Singh, Ruchi, Singh, Om P., Dash, Aditya P., Singh, Ashok K., Carlton, Jane M., Bhasin, Virendra K.

“…•Microsatellite markers revealed a geographic structure in Indian P. falciparum.•Four groups of subpopulations observed in Indian P. falciparum…”
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Monoterpene citral derivatives as potential antimalarials by Singh, Soni, Khandare, Reena P, Sharma, Manish, Bhasin, Virendra K, Bhat, Sujata V

“…Conjugated acid derivatives containing nitrogen have been synthesized from the simple acyclic monoterpene citral, using various reactions, including Wittig,…”
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Antiplasmodial interactions between artemisinin and triclosan or ketoconazole combinations against blood stages of Plasmodium falciparum in vitro by Mishra, Lokesh C, Bhattacharya, Amit, Bhasin, Virendra K

“…Emergence of drug-resistant Plasmodium falciparum strains to conventional first-line antimalarial drugs has compelled many countries to reorient their drug…”
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Plasmodium falciparum genetic diversity and ancestry by Bhasin, Virendra K

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ACT now--with caution--for malaria treatments by Bhasin, Virendra K, Nair, Lathika

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Could a website teach communication skills? by Bhasin, Virendra K

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Proteomics could be key in battle against malaria by Bhasin, Virendra K

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Gametocyte-forming and non-gametocyte-forming clones of Plasmodium falciparum by Bhasin, V K, Trager, W

“…Three clones have been prepared from the Honduras I/CDC strain of Plasmodium falciparum by a method of microscopic selection. One of these (HB-2) does not form…”
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In vitro gametocytocidal activity of artemisinin and its derivatives on Plasmodium falciparum by Mehra, N, Bhasin, V K

“…Artemisinin and six of its derivatives were evaluated for their in vitro gametocytocidal and erythrocytic schizontocidal properties on an Indian isolate of…”
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