Giant Parathyroid Adenoma: Are They Different?

Primary hyperparathyroidism is a common endocrinology anomaly which involves head and neck region. The diagnosis and treatment of parathyroid adenoma however still remains a challenge. Giant parathyroid adenomas are rare and involve more surgical expertise. Retrospective study was carried in Departm...

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Bibliographic Details
Published in:	Indian journal of otolaryngology, and head, and neck surgery Vol. 74; no. Suppl 2; pp. 1929 - 1932
Main Authors:	Grover, Mohnish, Sharma, Monika, Bhandari, Sudhir, Sharma, Balram, Bhargva, Shruti, Samdhani, Sunil
Format:	Journal Article
Language:	English
Published:	New Delhi Springer India 01-10-2022 Springer Nature B.V
Subjects:	Endocrinology Head and Neck Surgery Medicine Medicine & Public Health Original Original Article Otorhinolaryngology Tumors Primary hyperparathyroidism Raised serum calcium Giant parathyroid adenoma Recurrent laryngeal nerve
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Summary:	Primary hyperparathyroidism is a common endocrinology anomaly which involves head and neck region. The diagnosis and treatment of parathyroid adenoma however still remains a challenge. Giant parathyroid adenomas are rare and involve more surgical expertise. Retrospective study was carried in Departments of ENT and Endocrinology, SMS Medical College and Hospital, Jaipur. Records of patients operated between 2010 and 2019 were evaluated and analysed for size and site of parathyroid adenomas, biochemical parameters, intra-operative findings and postoperative course. Tumours with size > 3 cm were termed as giant parathyroid adenomas and this is a rarity in literature. Records of 79 patients were found to be complete. Out of these 9 had giant parathyroid adenomas: 4 left inferior, 2 right inferior, 1 ectopic location (superior mediastinum) and 1 each in left and right superior glands. The size, symptomatology and biochemical parameters are discussed in light of available literature. Giant parathyroid adenomas are a rare entity and their behaviour are same as of non giant parathyroid adenomas. In the view of literature published on pub Med, this is found to be largest case series on parathyroid Adenoma considering size more than 3 cm.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	2231-3796 0973-7707
DOI:	10.1007/s12070-020-01898-7