Search Results - "Bhardwaj, Rukmini"
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Identification of a novel role of IL-13Rα2 in human Glioblastoma multiforme: interleukin-13 mediates signal transduction through AP-1 pathway
Published in Journal of translational medicine (20-12-2018)“…Previously, we have demonstrated that Interleukin 13 receptor alpha 2 (IL-13Rα2) is overexpressed in approximate 78% Glioblastoma multiforme (GBM) samples. We…”
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Establishing CD19 B-cell reference control materials for comparable and quantitative cytometric expression analysis
Published in PloS one (19-03-2021)“…In the field of cell-based therapeutics, there is a great need for high-quality, robust, and validated measurements for cell characterization. Flow cytometry…”
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Malaria vaccine candidate based on Duffy-binding protein elicits strain transcending functional antibodies in a Phase I trial
Published in npj vaccines (28-09-2018)“…Reticulocyte invasion by Plasmodium vivax requires interaction of the Duffy-binding protein (PvDBP) with host Duffy antigen receptor for chemokines (DARCs)…”
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Antibody responses to Plasmodium vivax Duffy binding and Erythrocyte binding proteins predict risk of infection and are associated with protection from clinical Malaria
Published in PLoS neglected tropical diseases (01-02-2019)“…The Plasmodium vivax Duffy Binding Protein (PvDBP) is a key target of naturally acquired immunity. However, region II of PvDBP, which contains the…”
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Phase I Clinical Trial of a Recombinant Blood Stage Vaccine Candidate for Plasmodium falciparum Malaria Based on MSP1 and EBA175
Published in PloS one (30-04-2015)“…A phase I randomised, controlled, single blind, dose escalation trial was conducted to evaluate safety and immunogenicity of JAIVAC-1, a recombinant blood…”
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Production of recombinant PvDBPII, receptor binding domain of Plasmodium vivax Duffy binding protein, and evaluation of immunogenicity to identify an adjuvant formulation for vaccine development
Published in Protein expression and purification (01-08-2017)“…Plasmodium vivax is dependent on interaction with the Duffy antigen receptor for chemokines (DARC) for invasion of human erythrocytes. The P. vivax Duffy…”
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Correction: Phase I Clinical Trial of a Recombinant Blood Stage Vaccine Candidate for Plasmodium falciparum Malaria Based on MSP1 and EBA175
Published in PloS one (02-09-2015)“…[This corrects the article DOI: 10.1371/journal.pone.0117820.]…”
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ISCOMATRIX™ adjuvant promotes epitope spreading and antibody affinity maturation of influenza A H7N9 virus like particle vaccine that correlate with virus neutralization in humans
Published in Vaccine (31-07-2015)“…Highlights • H7N9 VLP vaccine with ISCOMATRIX™ adjuvant showed enhanced neutralizing antibody responses in humans. • Unadjuvanted H7N9-VLP vaccine generated…”
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Abstract 4900: Cysteamine suppresses tumor metastasis by inhibiting activity of matrix metalloproteases without inducing toxicity in mouse models of human ovarian cancer
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Previously, we demonstrated that cysteamine, a small molecule inhibitor of matrixmetalloproteases (MMPs), inhibited tumor invasion in vitro and metastasis in…”
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Abstract 2438: Analysis of IL-13 signaling through IL-13Rα2 in human brain tumor specimens in situ
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Previously, we have demonstrated that IL-13 receptor alpha2 (IL-13Rα2), a high affinity receptor for Th2 cytokine IL-13, is overexpressed in most glioblastoma…”
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Identification of a novel role of IL-13R[alpha]2 in human Glioblastoma multiforme: interleukin-13 mediates signal transduction through AP-1 pathway
Published in Journal of translational medicine (20-12-2018)“…Background Previously, we have demonstrated that Interleukin 13 receptor alpha 2 (IL-13R[alpha]2) is overexpressed in approximate 78% Glioblastoma multiforme…”
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12
Targeting TLRs expands the antibody repertoire in response to a malaria vaccine
Published in Science translational medicine (27-07-2011)“…Vaccination with an isolated antigen is frequently not sufficient to elicit a protective immune response. The addition of adjuvants to the antigen can increase…”
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Correction: Phase I Clinical Trial of a Recombinant Blood Stage Vaccine Candidate for Plasmodium falciparum Malaria Based on MSP1 and EBA175: e0137816
Published in PloS one (01-09-2015)Get full text
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