Search Results - "Bhardwaj, Nivedita"

In-silico identification of Coumarin-based natural compounds as potential VEGFR-2 inhibitors by Tripathi, Nancy, Bhardwaj, Nivedita, Singh, Bikarma, Jain, Shreyans K.

“…The coumarin nucleus is a simple privileged scaffold distributed in many plants. It has recently gained attention for its diverse biological activities and…”
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Small Molecule CDK Inhibitors for the Therapeutic Management of Cancer by Goel, Bharat, Tripathi, Nancy, Bhardwaj, Nivedita, Jain, Shreyans K

“…Cyclin-dependent kinases (CDKs) are a group of multifunctional enzymes consisting of catalytic and regulatory subunits. The regulatory subunit, cyclin, remains…”
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In-vitro Anti-inflammatory Potential of Standardized Rottlerin Enriched Fraction of Mallotus philippensis Muell. Arg Anti-inflammatory Potential of Rottlerin Enriched Fraction of Mallotus philippensis by Tripathi, Nancy, Mandrah, Kapil, Goel, Bharat, Bhardwaj, Nivedita, Paswan, Vinod Kumar, Ravikanth, G., Roy, Somendu K., Jain, Shreyans K.

“…A rottlerin enriched fraction was prepared from extract of Mallotus philippensis Muell. Arg leaves in ethyl acetate using HP-20 dianion polymeric resin. The…”
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Pharmacokinetic Assessment of Rottlerin from Mallotus philippensis Using a Highly Sensitive Liquid Chromatography–Tandem Mass Spectrometry-Based Bioanalytical Method by Manhas, Diksha, Gour, Abhishek, Bhardwaj, Nivedita, Sharma, Deepak K, Sharma, Kuhu, Vij, Bhavna, Jain, Shreyans K, Singh, Gurdarshan, Nandi, Utpal

“…Rottlerin is a key bioactive phytoconstituent present in the pericarp of Mallotus philippensis. It shows promising multifaceted pharmacological actions against…”
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A comprehensive review on chemistry and pharmacology of marine bioactives as antimetastatic agents by Bhardwaj, Nivedita, Goel, Bharat, Tripathi, Nancy, Sahu, Bharat, Jain, Shreyans K.

“…Metastasis by and large is responsible for the worldwide deaths associated with various types of cancers. The metastatic variant of cancer cells generated due…”
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Identification and Evaluation of Apoptosis-Inducing Activity of Ipomone from Ipomoea nil: A Novel, Unusual Bicyclo-[3.2.1] Octanone Containing Gibberic Acid Diterpenoid by Goel, Bharat, Chatterjee, Essha, Dey, Biswajit, Tripathi, Nancy, Bhardwaj, Nivedita, Khattri, Arun, Guru, Santosh Kumar, Jain, Shreyans K

“…Ipomone (1), a novel diterpenoid along with seven known compounds (2–8), was isolated for the first time from the acidified hydroalcoholic extract of Ipomoea…”
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Virtual screening and molecular simulation study of natural products database for lead identification of novel coronavirus main protease inhibitors by Tripathi, Nancy, Goel, Bharat, Bhardwaj, Nivedita, Sahu, Bharat, Kumar, Hemant, Jain, Shreyans K.

“…3CL like protease (3CLpro or Mpro) is one of the main proteases of 2019-nCoV. The 3CLpro is a nonstructural protein of SARS-CoV and has an essential role in…”
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Unveiling the potential of acetic acid-based hydrophobic natural deep eutectic solvents for phytochemical extraction by Srivastava, Rashi, Bhardwaj, Nivedita, Jain, Shreyans K., Metya, Atanu K., Parambil, Jose V.

“…•Acetic acid-based two reusable hydrophobic polar and non-polar NADES were developed.•Structural analysis of NADES by experimental and simulation…”
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Phytochemical and Pharmacological Aspects of Psoralen – A Bioactive Furanocoumarin from Psoralea corylifolia Linn by Tripathi, Nancy, Bhardwaj, Nivedita, Kumar, Sanjay, Jain, Shreyans K.

“…Since long ago, medicinal plants have played a vital role in drug discovery. Being blessed and rich in chemovars with diverse scaffolds, they have unique…”
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A machine learning‐based KNIME workflow to predict VEGFR‐2 inhibitors by Tripathi, Nancy, Bhardwaj, Nivedita, Kumar, Sanjay, Jain, Shreyans K.

“…Vascular endothelial growth factors (VEGFs) are specific cytokines involved in angiogenesis and do so via binding to vascular endothelial growth factor…”
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Identifying inflammation-related targets of natural lactones using network pharmacology, molecular modeling and in vitro approaches by Tripathi, Nancy, Saraf, Poorvi, Bhardwaj, Nivedita, Shrivastava, Sushant Kumar, Jain, Shreyans K

“…Natural lactones have been used in traditional and folklore medicine for centuries owing to their anti-inflammatory properties. The study uses a multifaceted…”
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In silico analysis, isolation, and cytotoxicity evaluation of the coumestans from Cullen corylifolium (L.) Medik by Tripathi, Nancy, Shah, Himisa, Bhardwaj, Nivedita, Sarkar, Ruma, Jain, Shreyans K.

“…Cullen corylifolium is well known for diverse phytoconstituents that possess multifaceted pharmacology, and one such less explored class is coumestans, which…”
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New cycloartane triterpenoids from Dysoxylum malabaricum and their cytotoxic evaluation by Bhardwaj, Nivedita, Sharma, Anamika, Tripathi, Nancy, Goel, Bharat, Ravikanth, G., Kumar Guru, Santosh, Jain, Shreyans K.

“…[Display omitted] •Four cycloartane type triterpenoids (1–4) were isolated from the bark of Dysoxylum malabaricum.•Dereplication strategy was used to identify…”
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Isolation, Cytotoxicity, and In‐silico Screening of Coumarins from Psoralea corylifolia Linn by Tripathi, Nancy, Parmar, Aarati, Pandey, Nilesh, Bhardwaj, Nivedita, Chakrabarty, Sanheeta, Sarkar, Ruma, Kumar, Hemant, Jain, Shreyans K.

“…Psoralea corylifolia (syn. Cullen corylifolium), commonly called bawachi, is a medicinal plant extensively used for skin conditions like leukoderma, vitiligo,…”
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Iodine-mediated one-step synthesis of ipomone from gibberellic acid by Goel, Bharat, Tripathi, Nancy, Bhardwaj, Nivedita, Kumar, Amit, Jain, Shreyans K.

“…A fast and efficient method for synthesising ipomone (4), a bicyclo[3.2.1]octanone containing aromatised derivative, from gibberellic acid (1) has been…”
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New ring-A modified cycloartane triterpenoids from Dysoxylum malabaricum bark: Isolation, structure elucidation and their cytotoxicity by Bhardwaj, Nivedita, Gupta, Priyamvada, Tripathi, Nancy, Chakrabarty, Sanheeta, Verma, Ashish, Kumari, Sanju, Gautam, Vibhav, Ravikanth, G., Jain, Shreyans K.

“…[Display omitted] •Genus Dysoxylum is a rich source of structurally diverse triterpenoids having medicinal importance.•New ring-A modified bioactive…”
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Prioritization of the Secondary Metabolites for the Rapid Annotation Based on Liquid Chromatography-High Resolution Mass Spectrometry Assessment: Varanasine and Schroffanone from Murraya paniculata and Cytotoxic Evaluation by Kumari, Sanju, Prathyusha, Bhavana, Chatterjee, Essha, Tripathi, Nancy, Chakrabarty, Sanheeta, Bhardwaj, Nivedita, Guru, Santosh Kumar, Agastinose Ronickom, Jac Fredo, Jain, Shreyans K.

“…The liquid chromatography-high resolution mass spectrometry (LC-HRMS) technique enables the detection of phytochemicals present in the extracts…”
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In-vitro antitumor activity of compounds from Glycyrrhiza glabra against C6 glioma cancer cells: identification of natural lead for further evaluation by Goel, Bharat, Sharma, Anuradha, Tripathi, Nancy, Bhardwaj, Nivedita, Sahu, Bharat, Kaur, Gurcharan, Singh, Bikarma, Jain, Shreyans K.

“…A HP20 resin-based unique method was adopted to get an active fraction of the hydroalcoholic extract of G. glabra roots. The fraction showed potent…”
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Synthesis and molecular docking studies of quinoline derivatives as HIV non-nucleoside reverse transcriptase inhibitors by Bhardwaj, Nivedita, Choudhary, Diksha, Pathania, Akashdeep, Baranwal, Somesh, Kumar, Pradeep

“…Quinoline moiety is an important scaffold in the field of drug discovery and drug development, with a wide range of pharmacological activities. Quinoline…”
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Semisynthesis: An Essential Tool for Antibiotics Drug Discovery by Goel, Bharat, Tripathi, Nancy, Bhardwaj, Nivedita, Pal Singh, Inder, Jain, Shreyans K.

“…The continuous emergence of antimicrobial resistance (AMR) is a serious threat to humans. The discovery and development of new antibiotics having new modes of…”
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