Search Results - "Bhamidipati, Ravi K"
-
1
Simultaneous determination of OZ277, a synthetic 1,2,4-trioxolane antimalarial, and its polar metabolites in rat plasma using hydrophilic interaction chromatography
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-10-2009)“…OZ277 is a synthetic 1,2,4-trioxolane antimalarial currently being evaluated in clinical trails. Biotransformation of OZ277 in rats results in the generation…”
Get full text
Journal Article -
2
Design, Synthesis of Novel, Potent, Selective, Orally Bioavailable Adenosine A2A Receptor Antagonists and Their Biological Evaluation
Published in Journal of medicinal chemistry (26-01-2017)“…Our initial structure–activity relationship studies on 7-methoxy-4-morpholino-benzothiazole derivatives featured by aryloxy-2-methylpropanamide moieties at the…”
Get full text
Journal Article -
3
Design, Synthesis of Novel, Potent, Selective, Orally Bioavailable Adenosine A 2A Receptor Antagonists and Their Biological Evaluation
Published in Journal of medicinal chemistry (26-01-2017)“…Our initial structure-activity relationship studies on 7-methoxy-4-morpholino-benzothiazole derivatives featured by aryloxy-2-methylpropanamide moieties at the…”
Get full text
Journal Article -
4
Discovery of Potent and Selective A2A Antagonists with Efficacy in Animal Models of Parkinson’s Disease and Depression
Published in ACS medicinal chemistry letters (10-08-2017)“…Adenosine A2A receptor (A2AAdoR) antagonism is a nondopaminergic approach to Parkinson’s disease treatment that is under development. Earlier we had reported…”
Get full text
Journal Article -
5
Discovery of Potent and Selective A 2A Antagonists with Efficacy in Animal Models of Parkinson's Disease and Depression
Published in ACS medicinal chemistry letters (10-08-2017)“…Adenosine A receptor (A AdoR) antagonism is a nondopaminergic approach to Parkinson's disease treatment that is under development. Earlier we had reported the…”
Get full text
Journal Article