Search Results - "Bhalla, D. K."

Amelioration of Ozone-Induced Lung Injury by Anti-Tumor Necrosis Factor-α by Bhalla, Deepak K., Reinhart, Paul G., Bai, Cheng, Gupta, Suresh K.

“…Ozone (O3) is a significant component of atmospheric air pollution and produces detrimental effects in the lung. Although the mechanism of O3-induced lung…”
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Interactive effects of Cigarette Smoke and ozone in the induction of Lung Injury by BHALLA, Deepak K

“…The article highlighted in this issue is "Short-Term Exposure to Aged and Diluted Sidestream Cigarette Smoke Enhances Ozone-Induced Lung Injury in B6C3F1 Mice"…”
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OXIDATIVE EFFECTS AND INFLAMMATORY RESPONSES IN THE LUNG by Bhalla, D. K.

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Surfactant dysfunction after inhalation of nitric oxide by Hallman, M, Waffarn, F, Bry, K, Turbow, R, Kleinman, M T, Mautz, W J, Rasmussen, R E, Bhalla, D K, Phalen, R F

“…To study whether nitric oxide (NO) affects surfactant function, 36 young rats inhaled one of the following humidified environments for 24 h: 1) air; 2) 95% O2;…”
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Enhancement of fibronectin expression in rat lung by ozone and an inflammatory stimulus by Gupta, S K, Reinhart, P G, Bhalla, D K

“…This study investigated the relationship of fibronectin expression and induction of pulmonary inflammation by ozone (O3). Rats were exposed to 0.8…”
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Attenuation of ozone-induced lung injury by interleukin-10 by Reinhart, Paul G, Gupta, Suresh K, Bhalla, Deepak K

“…Ozone (O 3), an oxidant air pollutant, is capable of producing pulmonary inflammation and injury. Exposure to O 3 results in the release of inflammatory…”
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Alteration of ozone-induced airway permeability by oxygen metabolites and antioxidants by Bhalla, D K

“…This study determined the interactive effects of O3 and enzymatically-generated oxidants and antioxidants in the lung. Rats treated with dimethylthiourea…”
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OZONE-INDUCED LUNG INFLAMMATION AND MUCOSAL BARRIER DISRUPTION: TOXICOLOGY, MECHANISMS, AND IMPLICATIONS by Bhalla, Deepak K.

“…The airway epithelial lining serves as an efficient barrier against penetration of exogenous particles and macromolecules. Disruption of this barrier following…”
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ALTERATION OF EPITHELIAL INTEGRITY, ALKALINE PHOSPHATASE ACTIVITY, AND FIBRONECTIN EXPRESSION IN LUNGS OF RATS EXPOSED TO OZONE by Bhalla, D K, Gupta, S K, Reinhart, P G

“…The deleterious effects of ozone (O3), an oxidant air pollutant, in the lung are dependent on dose and exposure duration and generally evolve with time…”
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Attenuation of ozone-induced airway permeability in rats by pretreatment with cyclophosphamide, FPL 55712, and indomethacin by Bhalla, D K, Daniels, D S, Luu, N T

“…Exposure of rats to ozone (O3) produces an increase in airway permeability and a concomitant influx of polymorphonuclear leukocytes in the lung. These…”
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Adhesion and motility of polymorphonuclear leukocytes isolated from the blood of rats exposed to ozone: potential biomarkers of toxicity by Bhalla, D K, Rasmussen, R E, Daniels, D S

“…Ozone (O3) exposure of rats results in airway epithelial injury and an infiltration of polymorphonuclear leukocytes (PMNs) into the lungs, suggesting…”
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The influence of polymorphonuclear leukocytes on altered pulmonary epithelial permeability during ozone exposure by Reinhart, Paul G, Bassett, David J.P, Bhalla, Deepak K

“…Ozone (O 3), a pulmonary irritant, and a major toxic component of photochemical smog, is capable of inducing pulmonary inflammation characterized by…”
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Biological agents with potential for misuse: a historical perspective and defensive measures by Bhalla, Deepak K, Warheit, David B

“…Biological and chemical agents capable of producing serious illness or mortality have been used in biowarfare from ancient times. Use of these agents has…”
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Modification of macrophage adhesion by ozone: role of cytokines and cell adhesion molecules by Bhalla, D K, Hoffman, L A, Pearson, A C

“…The inflammatory response in the lungs following an inhalation exposure of animals and humans to ozone (O3) is associated with macrophage stimulation, release…”
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Effects of ozone on the epithelial and inflammatory responses in the airways: role of tumor necrosis factor by Young, C, Bhalla, D K

“…We have investigated the possibility that tumor necrosis factor alpha (TNF) plays a role in the increased airway permeability and an inflammatory response…”
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LUNG INJURY, INFLAMMATION, AND INFLAMMATORY STIMULI IN RATS EXPOSED TO OZONE by Gupta, D.K. Bhalla, S.K.

“…The effects of ozone (O 3 ) on airway epithelia, inflammation, and expression of inflammatory stimuli were investigated to delineate the mechanisms of inflam…”
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Model for Capping Derived from Inhibition of Surface Receptor Capping by Free Fatty Acids by Klausner, R. D., Bhalla, D. K., Dragsten, P., Hoover, R. L., Karnovsky, M. J.

“…When low concentrations (2-5 mole%) of cis unsaturated free fatty acids (group A) are intercalated into lymphocyte plasma membrane, capping is inhibited. No…”
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Cell renewal and migration in lymphoid follicles of Peyer's patches and cecum--an autoradiographic study in mice by Bhalla, D K, Owen, R L

“…Peyer's patch lymphoid follicles are characterized by a cuboidal epithelium, which has low numbers of mucus-secreting goblet cells, infiltration with clusters…”
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Effects of ozone on macrophage adhesion in vitro and epithelial and inflammatory responses in vivo: the role of cytokines by Pearson, A C, Bhalla, D K

“…Inhalation exposure to ozone (O3) is known to induce epithelial and inflammatory changes in the lungs, characterized by neutrophilia and changes in epithelial…”
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Inhalation of resuspended road dust, but not ammonium nitrate, decreases the expression of the pulmonary macrophage Fc receptor by Ziegler, B, Bhalla, D K, Rasmussen, R E, Kleinman, M T, Menzel, D B

“…Pulmonary macrophages (PM) play a key role in the immune defenses of the lung. When stimulated, PM express Fc receptors (FcR) that regulate the immune…”
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