Seroprevalence of Anti-Citrullinated Protein Antibodies (ACPA) in Patients with Rheumatic Diseases other than Rheumatoid Arthritis

To evaluate the prevalence of anti- citrullinated protein antibodies (ACPA) in patients with a variety of rheumatic diseases other than rheumatoid arthritis (RA). 144 cases of rheumatic diseases other than rheumatoid arthritis (RA) over a period of 1 year were recruited after consenting and followed...

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Bibliographic Details
Published in:Journal of the Association of Physicians of India Vol. 66; no. 4; pp. 26 - 28
Main Authors: Saigal, Renu, Bhakal, Surendra Singh, Goyal, Laxmikant, Goel, Akhil D
Format: Journal Article
Language:English
Published: India 01-04-2018
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Summary:To evaluate the prevalence of anti- citrullinated protein antibodies (ACPA) in patients with a variety of rheumatic diseases other than rheumatoid arthritis (RA). 144 cases of rheumatic diseases other than rheumatoid arthritis (RA) over a period of 1 year were recruited after consenting and followed up for 2 years. Their serum samples were tested for ACPA. ACPA seropositivity of 9.03% was observed in rheumatic diseases other than RA. Whether ACPA seropositivity in non-RA rheumatic diseases indicates a false positive result or an overlap RA syndrome is a mystery yet unsolved. Long term follow ups of these patients will be required to understand the course of rheumatic diseases in relation to ACPA..
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ISSN:0004-5772