Search Results - "Bhagat, G."

EBV-associated primary CNS lymphoma occurring after immunosuppression is a distinct immunobiological entity by Gandhi, M.K., Hoang, T., Law, S.C., Brosda, S., O'Rourke, K., Tobin, J.W.D., Vari, F., Murigneux, V., Fink, L., Gunawardana, J., Gould, C., Oey, H., Bednarska, K., Delecluse, S., Trappe, R.U., Merida de Long, L., Sabdia, M.B., Bhagat, G., Hapgood, G., Blyth, E., Clancy, L., Wight, J., Hawkes, E., Rimsza, L.M., Maguire, A., Bojarczuk, K., Chapuy, B., Keane, C.

“…Primary central nervous system lymphoma (PCNSL) is confined to the brain, eyes, and cerebrospinal fluid without evidence of systemic spread. Rarely, PCNSL…”
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FoxO1-dependent induction of acute myeloid leukemia by osteoblasts in mice by Kode, A, Mosialou, I, Manavalan, S J, Rathinam, C V, Friedman, R A, Teruya-Feldstein, J, Bhagat, G, Berman, E, Kousteni, S

“…Osteoblasts, the bone forming cells, affect self-renewal and expansion of hematopoietic stem cells (HSCs), as well as homing of healthy hematopoietic cells and…”
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IL10 receptor is a novel therapeutic target in DLBCLs by Béguelin, W, Sawh, S, Chambwe, N, Chan, F C, Jiang, Y, Choo, J-W, Scott, D W, Chalmers, A, Geng, H, Tsikitas, L, Tam, W, Bhagat, G, Gascoyne, R D, Shaknovich, R

“…Diffuse large B-cell lymphoma (DLBCL) is a biologically and clinically heterogeneous disease with marked genomic instability and variable response to…”
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OP06.04: Correlation of fetal soft tissue with neonatal body composition by Dadhwal, V., Bhagat, G., Jain, V., Sharma, A., Kochhar, K., Vanamail, P., Deka, D., Malhotra, N.

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Phenotypic shift of small intestinal intra‐epithelial type 1 innate lymphoid cells in celiac disease is associated with enhanced cytotoxic potential by Uhde, M., Yu, X., Bunin, A., Brauner, C., Lewis, S. K., Lebwohl, B., Krishnareddy, S., Alaedini, A., Reizis, B., Ghosh, S., Green, P. H., Bhagat, G.

“…Summary The small intestinal (SI) epithelium harbors a heterogeneous population of lymphocytes that mediate mucosal damage and repair in celiac disease (CD)…”
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Concordant bone marrow involvement of diffuse large B-cell lymphoma represents a distinct clinical and biological entity in the era of immunotherapy by Yao, Z, Deng, L, Xu-Monette, Z Y, Manyam, G C, Jain, P, Tzankov, A, Visco, C, Bhagat, G, Wang, J, Dybkaer, K, Tam, W, Hsi, E D, van Krieken, J H, Ponzoni, M, Ferreri, A J M, Møller, M B, Winter, J N, Piris, M A, Fayad, L, Liu, Y, Song, Y, Orlowski, R Z, Kantarjian, H, Medeiros, L J, Li, Y, Cortes, J, Young, K H

“…In diffuse large B-cell lymphoma (DLBCL), the clinical and biological significance of concordant and discordant bone marrow (BM) involvement have not been well…”
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Loss of PRDM1/BLIMP-1 function contributes to poor prognosis of activated B-cell-like diffuse large B-cell lymphoma by Xia, Y, Xu-Monette, Z Y, Tzankov, A, Li, X, Manyam, G C, Murty, V, Bhagat, G, Zhang, S, Pasqualucci, L, Visco, C, Dybkaer, K, Chiu, A, Orazi, A, Zu, Y, Richards, K L, Hsi, E D, Choi, W W L, van Krieken, J H, Huh, J, Ponzoni, M, Ferreri, A J M, Møller, M B, Parsons, B M, Winter, J N, Piris, M A, Westin, J, Fowler, N, Miranda, R N, Ok, C Y, Li, Y, Li, J, Medeiros, L J, Young, K H

“…PRDM1 /BLIMP-1, a master regulator of plasma-cell differentiation, is frequently inactivated in activated B-cell-like (ABC) diffuse large B-cell lymphoma…”
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Long-term follow-up of complete Barrett's eradication endoscopic mucosal resection (CBE-EMR) for the treatment of high grade dysplasia and intramucosal carcinoma by Larghi, A, Lightdale, C J, Ross, A S, Fedi, P, Hart, J, Rotterdam, H, Noffsinger, A, Memeo, L, Bhagat, G, Waxman, I

“…In patients with Barrett's esophagus (BE), targeted endoscopic mucosal resection (EMR) of visible lesions of high grade dysplasia (HGD) or intramucosal…”
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Early B-cell-specific inactivation of ATM synergizes with ectopic CyclinD1 expression to promote pre-germinal center B-cell lymphomas in mice by Yamamoto, K, Lee, B J, Li, C, Dubois, R L, Hobeika, E, Bhagat, G, Zha, S

“…Ataxia telangiectasia-mutated (ATM) kinase is a master regulator of the DNA damage response. ATM is frequently inactivated in human B-cell non-Hodgkin…”
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A study to explore the risk factors for the early onset of cataract in India by Praveen, M R, Shah, G D, Vasavada, A R, Mehta, P G, Gilbert, C, Bhagat, G

“…Purpose The aim of this study was to identify risk factors for the development of cataract in young patients. Settings The study was undertaken at Iladevi…”
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Role of bone marrow-derived cells in experimental chronic pancreatitis by Marrache, F, Pendyala, S, Bhagat, G, Betz, K S, Song, Z, Wang, T C

“…Chronic pancreatitis is a known risk factor for pancreatic adenocarcinoma. Recent work has pointed to a role for bone marrow-derived progenitor cells (BMDCs)…”
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Administration of fasudil, a ROCK inhibitor, attenuates disease in lupus-prone NZB/W F1 female mice by Stirzaker, RA, Biswas, PS, Gupta, S, Song, L, Bhagat, G, Pernis, AB

“…Accumulating evidence from murine studies suggests that the RhoA/ROCK pathway plays an important role in the development of autoimmune disorders. We previously…”
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GENETIC AND PHENOTYPIC ATTRIBUTES OF SPLENIC MARGINAL ZONE LYMPHOMA by Bonfiglio, F., Bruscaggin, A., Guidetti, F., Terzi di Bergamo, L., Faderl, M., Spina, V., Condoluci, A., Bonomini, L., Forestieri, G., Koch, R., Piffaretti, D., Pini, K., Pirosa, M. C., Cittone, M. G., Arribas, A., Lucioni, M., Ghilardi, G., Wu, W., Arcaini, L., Baptista, M. J., Bastidas, G., Bea, S., Boldorini, R., Broccoli, A., Canzonieri, V., Cascione, L., Ceriani, L., Cogliatti, S., Derenzini, E., Devizzi, L., Dietrich, S., Elia, A. R., Facchetti, F., Gaidano, G., Garcia, J. F., Gerber, B., Ghia, P., Da Silva, M. G., Gritti, G., Guidetti, A., Hitz, F., Inghirami, G., Ladetto, M., Lopez‐Guillermo, A., Lucchini, E., Maiorana, A., Marasca, R., Matutes, E., Meignin, V., Merli, M., Moccia, A., Mollejo, M., Montalban, C., Novak, U., Oscier, D. G., Passamonti, F., Piazza, F., Pizzolitto, S., Sabattini, E., Salles, G., Santambrogio, E., Scarfó, L., Stathis, A., Stüssi, G., Geyer, J. T., Tapia, G., Thieblemont, C., Tousseyn, T., Tucci, A., Visco, C., Vitolo, U., Zenz, T., Zinzani, P. L., Khiabanian, H., Calcinotto, A., Bertoni, F., Bhagat, G., Campo, E., De Leval, L., Dirnhofer, S., Pileri, S. A., Piris, M. Án., Traverse‐Glehen, A., Tzankov, A., Paulli, M., Ponzoni, M., Mazzucchelli, L., Cavalli, F., Zucca, E., Rossi, D.

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Addition of rituximab to chemotherapy overcomes the negative prognostic impact of cyclin E expression in diffuse large B-cell lymphoma by Frei, E, Visco, C, Xu-Monette, Z Y, Dirnhofer, S, Dybkær, K, Orazi, A, Bhagat, G, Hsi, E D, van Krieken, J H, Ponzoni, M, Go, R S, Piris, M A, Møller, M B, Young, K H, Tzankov, A

“…High levels of cyclin E (CCNE) are accompanied by shorter survival in cyclophosphamide, hydroxydaunorubicin, oncovin and prednisone (CHOP)-treated diffuse…”
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TARGETING THE PERIPHERAL T‐CELL LYMPHOMA (PTCL) EPIGENOME WITH ORAL 5‐AZACYTIDINE AND ROMIDEPSIN: RESULTS AND CLINICAL‐MOLECULAR CORRELATIONS FROM A PHASE 2 STUDY by Falchi, L., Lue, J.K., Montanari, F., Marchi, E., Amengual, J.E., Sawas, A., Deng, C., Khan, K., Kim, H.A., Rada, A., Malanga, M., Francescone, M.F., Soderquist, C.R., Park, D.C., Bhagat, G., Sokol, L., Shustov, A.R., O'Connor, O.A.

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EBV+ CNS LYMPHOMAS HAVE A DISTINCTIVE TUMOR MICROENVIRONMENT AND GENETIC PROFILE, WHICH IS AMENABLE TO COMBINATION 3RD PARTY EBV‐SPECIFIC CTL AND IBRUTINIB THERAPY by Gandhi, M.K., Hoang, T., Tobin, J.W., Law, S.C., Talaulikar, D., Jain, S., Vari, F., Murigneux, V., Fink, L., Gunawardana, J., Gould, C., Oey, H., Delecluse, S., Trappe, R.U., Merida de Long, L., Sabdia, M.B., Bhagat, G., Hapgood, G., Blyth, E., Clancy, L., Casey, J., Wight, J., Hawkes, E., Keane, C.

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Lack of correlation of degree of villous atrophy with severity of clinical presentation of coeliac disease by Brar, P, Kwon, G.Y, Egbuna, I.I, Holleran, S, Ramakrishnan, R, Bhagat, G, Green, P.H.R

“…Abstract Background and aim Both the clinical presentation and the degree of mucosal damage in coeliac disease vary greatly. In view of conflicting information…”
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P076 Abnormal rock activity in CD4+ T cells upregulates IL-21 production and promotes type 1 diabetes in NOD mice by Biswas, P., Gupta, S., Chang, E., Bhagat, G., Pernis, A.

“…Aberrant production of IL-21 by CD4+ T cells play important role in the development of type 1 diabetes (T1D) in NOD mice. The pathogenic effects of IL-21 are…”
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Deregulated expression of HDAC9 in B-cells promotes development of lymphoproliferative disease and lymphoma by Gil, V. S., Bhagat, G., Howell, L., Zhang, J., Kim, C. H., Stengel, S., Vega, F., Zelent, A., Petrie, K.

“…Histone Deacetylase 9 (HDAC9) is expressed in B-cells and its overexpression has been observed in B-lymphoproliferative disorders and B-cell non-Hodgkin…”
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MULTI‐OMICS LANDSCAPE OF SPLENIC MARGINAL ZONE LYMPHOMA (SMZL) ‐ INTERIM ANALYSIS OF IELSG46 STUDY by Bruscaggin, A., Mollejo, M., Tapia, G., Gomes da Silva, M., Novak, U., Dietrich, S., Ponzoni, M., Rambaldi, A., Corradini, P., Vitolo, U., Merli, M., Tzankov, A., Cogliatti, S., Montalban, C., Marasca, R., Leval, L., Visco, C., Baptista, M.J., Tousseyn, T., Facchetti, F., Paulli, M., Mazzucchelli, L., Bea, S., Oscier, D., Zinzani, P., Bhagat, G., Inghirami, G., Gaidano, G., Traverse‐Glehen, A., Thieblemont, C., Piris, M.A., Cavalli, F., Arcaini, L., Zucca, E., Rossi, D.

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