Search Results - "Bhagat, Chirag"

North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies by Shah, Urvi A., Chung, Elaine Y., Giricz, Orsi, Pradhan, Kith, Kataoka, Keisuke, Gordon-Mitchell, Shanisha, Bhagat, Tushar D., Mai, Yun, Wei, Yongqiang, Ishida, Elise, Choudhary, Gaurav S., Joseph, Ancy, Rice, Ronald, Gitego, Nadege, Parrish, Crystall, Bartenstein, Matthias, Goel, Swati, Mantzaris, Ioannis, Shastri, Aditi, Derman, Olga, Binder, Adam, Gritsman, Kira, Kornblum, Noah, Braunschweig, Ira, Bhagat, Chirag, Hall, Jeff, Graber, Armin, Ratner, Lee, Wang, Yanhua, Ogawa, Seishi, Verma, Amit, Ye, B. Hilda, Janakiram, Murali

“…Adult T-cell leukemia lymphoma (ATLL) is a rare T cell neoplasm that is endemic in Japanese, Caribbean, and Latin American populations. Most North American…”
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Stem cell mutations can be detected in myeloma patients years before onset of secondary leukemias by Sridharan, Ashwin, Schinke, Carolina D., Georgiev, George, Da Silva Ferreira, Mariana, Thiruthuvanathan, Victor, MacArthur, Ian, Bhagat, Tushar D., Choudhary, Gaurav S., Aluri, Srinivas, Chen, Jiahao, Pradhan, Kith, Xia, Yu, Panjikaran, Maya, Sims, Gregory, Bhagat, Chirag K., Bender, Ryan, Keeler, Lauryn, Graber, Armin, Heuck, Christoph, Fletcher, Frederick A., Alapat, Daisy, Weinhold, Niels, Johnson, Sarah K., Wickrema, Amittha, Barlogie, Bart, Morgan, Gareth J., Shastri, Aditi, Steidl, Ulrich, Will, Britta, Verma, Amit

“…Therapy-related acute myeloid leukemia and myelodysplastic syndromes (t-AML/t-MDS) are secondary hematologic malignancies associated with poor prognosis,…”
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Molecular annotation of extramedullary acute myeloid leukemia to identify prevalence of targetable mutations by Ball, Somedeb, Knepper, Todd C, Deutsch, Yehuda Ethan, Bhagat, Chirag K, Watts, Justin M., Bradley, Terrence J, Samra, Wassim, Chan, Onyee, Hussaini, Mohammad Omar, Sweet, Kendra L, Talati, Chetasi, Padron, Eric, Komrokji, Rami S., Lancet, Jeffrey E., Sallman, David Andrew

“…Abstract only 7024 Background: Extramedullary (EM) involvement, including myeloid sarcoma (MS) and leukemia cutis (LC), is uncommon in patients with acute…”
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Increased Frequency of IDH1/2 Mutations in Extramedullary Acute Myeloid Leukemia by Knepper, Todd C., Deutsch, Yehuda E., Bhagat, Chirag K, Watts, Justin M, Bradley, Terrence J, Samra, Wassim, Hussaini, Mohammad Omar, Sweet, Kendra L., Talati, Chetasi, Padron, Eric, Komrokji, Rami S., Lancet, Jeffrey E., Sallman, David A

“…Introduction The identification of somatic genomic alterations in cancer has brought forth a paradigm change in the personalized management of patients with…”
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Phase 1b/2 Combination Study of APR-246 and Azacitidine (AZA) in Patients with TP53 mutant Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) by Sallman, David A, DeZern, Amy E., Steensma, David P., Sweet, Kendra L., Cluzeau, Thomas, Sekeres, Mikkael A., Garcia-Manero, Guillermo, Roboz, Gail J., McLemore, Amy F, McGraw, Kathy L, Puskas, John, Zhang, Ling, Bhagat, Chirag K, Yao, Jiqiang, Al Ali, Najla, Padron, Eric, Tell, Roger, Lancet, Jeffrey E., Fenaux, Pierre, List, Alan F., Komrokji, Rami S.

“…Introduction: TP53 mutant (mTP53) MDS and AML, accounting for 5-10% of de novo MDS and 25-30% of therapy related MDS (t-MDS), represent a distinct molecular…”
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Abstract CT068: Phase Ib/II combination study of APR-246 and azacitidine (AZA) in patients with TP53 mutant myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) by Sallman, David A., DeZern, Amy, Sweet, Kendra, Steensma, David P., Cluzeau, Thomas, Sekeres, Mikkael, Garcia-Manero, Guillermo, Roboz, Gail, McLemore, Amy, McGraw, Kathy, Puskas, John, Zhang, Ling, Bhagat, Chirag, Graber, Armin, Ali, Najla H. Al, Padron, Eric, Tell, Roger, Lancet, Jeffrey E., Fenaux, Pierre, List, Alan F., Komrokji, Rami S.

“…Abstract Introduction: TP53 mutant (mTP53) MDS and AML represent a distinct molecular cohort with poor outcomes. Hypomethylating agents (HMA) have emerged as…”
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AML-Associated Somatic Mutations Can be Detected in Stem and Progenitor Populations in Patients with Antecedent Multiple Myeloma Years before Onset of Therapy-Related Transformation by Sridharan, Ashwin, Schinke, Carolina D., Georgiev, George, Da Silva Ferreira, Mariana, Pradhan, Kith, Xia, Yu, Panjikaran, Maya, Sims, Gregory, Bhagat, Chirag, Graber, Armin, Heuck, Christoph, Alapat, Daisy, Weinhold, Niels, Johnson, Sarah K, Barlogie, Bart, Morgan, Gareth J., Steidl, Ulrich G., Will, Britta, Verma, Amit

“…Introduction: Clonal hematopoiesis is an increasingly well-established risk factor for developing therapy-related acute myeloid leukemia and myelodysplastic…”
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Unusual Levels of Oxygen Consumption by Coproporphyrinogen Oxidase by Morgenthaler, Justin Bradley, Bhagat, Chirag, Lash, Timothy, Jones, Marjorie

“…The enzyme Coproporphyrinogen Oxidase (CO) is the sixth enzyme in the biosynthetic pathway for heme. This particular enzyme carries out two sequential…”
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