Search Results - "Bezzecchi, Eugenia"
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NF-Y Overexpression in Liver Hepatocellular Carcinoma (HCC)
Published in International journal of molecular sciences (01-12-2020)“…NF-Y is a pioneer trimeric transcription factor formed by the Histone Fold Domain (HFD) NF-YB/NF-YC subunits and NF-YA. Three subunits are required for DNA…”
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NF-Y subunits overexpression in gastric adenocarcinomas (STAD)
Published in Scientific reports (09-12-2021)“…NF-Y is a pioneer transcription factor—TF—formed by the Histone-like NF-YB/NF-YC subunits and the regulatory NF-YA. It binds to the CCAAT box, an element…”
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CAR T cell manufacturing from naive/stem memory T lymphocytes enhances antitumor responses while curtailing cytokine release syndrome
Published in The Journal of clinical investigation (15-06-2022)“…Chimeric antigen receptor (CAR) T cell expansion and persistence represent key factors to achieve complete responses and prevent relapses. These features are…”
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NF-YA Overexpression in Lung Cancer: LUSC
Published in Genes (17-11-2019)“…The CCAAT box is recognized by the trimeric transcription factor NF-Y, whose NF-YA subunit is present in two major splicing isoforms, NF-YAl ("long") and…”
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Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier
Published in eLife (25-10-2022)“…Hepatic metastases are a poor prognostic factor of colorectal carcinoma (CRC) and new strategies to reduce the risk of liver CRC colonization are highly…”
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The pancancer overexpressed NFYC Antisense 1 controls cell cycle mitotic progression through in cis and in trans modes of action
Published in Cell death & disease (11-03-2024)“…Antisense RNAs (asRNAs) represent an underappreciated yet crucial layer of gene expression regulation. Generally thought to modulate their sense genes in cis…”
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Combined unsupervised and semi-automated supervised analysis of flow cytometry data reveals cellular fingerprint associated with newly diagnosed pediatric type 1 diabetes
Published in Frontiers in immunology (27-10-2022)“…An unbiased and replicable profiling of type 1 diabetes (T1D)-specific circulating immunome at disease onset has yet to be identified due to experimental and…”
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MIR205HG/LEADR Long Noncoding RNA Binds to Primed Proximal Regulatory Regions in Prostate Basal Cells Through a Triplex- and Alu-Mediated Mechanism
Published in Frontiers in cell and developmental biology (17-06-2022)“…Aside serving as host gene for miR-205 , MIR205HG transcribes for a chromatin-associated long noncoding RNA (lncRNA) able to restrain the differentiation of…”
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Fat-to-blood recirculation of partially dysfunctional PD-1+CD4 Tconv cells is associated with dysglycemia in human obesity
Published in iScience (15-03-2024)“…Obesity is characterized by the accumulation of T cells in insulin-sensitive tissues, including the visceral adipose tissue (VAT), that can interfere with the…”
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NF-YA Overexpression in Lung Cancer: LUAD
Published in Genes (14-02-2020)“…The trimeric transcription factor (TF) NF-Y regulates the CCAAT box, a DNA element enriched in promoters of genes overexpressed in many types of cancer. The…”
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NF-Y Subunits Overexpression in HNSCC
Published in Cancers (16-06-2021)“…NF-Y is the CCAAT-binding trimer formed by the histone fold domain (HFD), NF-YB/NF-YC and NF-YA. The CCAAT box is generally prevalent in promoters of “cancer”…”
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The pancancer overexpressed NFYCAntisense 1 controls cell cycle mitotic progression through in cis and in trans modes of action
Published in Cell death & disease (01-03-2024)“…Antisense RNAs (asRNAs) represent an underappreciated yet crucial layer of gene expression regulation. Generally thought to modulate their sense genes in cis…”
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Fat Tissue-Derived PD1+CD4 T Cells Are Pro-inflammatory and Recirculating in Obese Patients with T2D
Published in Obesity (Silver Spring, Md.) (01-12-2021)“…Background: Chronic low-grade inflammation of the visceral adipose tissue (VAT) in obesity leads to insulin resistance (IR) and type 2 diabetes (T2D). Growing…”
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14
Continuous sensing of IFN[alpha] by hepatic endothelial cells shapes a vascular antimetastatic barrier
Published in eLife (25-10-2022)“…Hepatic metastases are a poor prognostic factor of colorectal carcinoma (CRC) and new strategies to reduce the risk of liver CRC colonization are highly…”
Get full text
Journal Article