Search Results - "Bezuglov, V. V."

ACTH(6–9)PGP Peptide Protects SH-SY5Y Cells from H2O2, tert-Butyl Hydroperoxide, and Cyanide Cytotoxicity via Stimulation of Proliferation and Induction of Prosurvival-Related Genes by Akimov, Mikhail G., Fomina-Ageeva, Elena V., Dudina, Polina V., Andreeva, Ludmila A., Myasoyedov, Nikolay F., Bezuglov, Vladimir V.

“…Stabilized melanocortin analog peptide ACTH(6–9)PGP (HFRWPGP) possesses a wide range of neuroprotective activities. However, its mechanism of action remains…”
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The Mechanisms of GPR55 Receptor Functional Selectivity during Apoptosis and Proliferation Regulation in Cancer Cells by Akimov, Mikhail G, Gretskaya, Natalia M, Dudina, Polina V, Sherstyanykh, Galina D, Zinchenko, Galina N, Serova, Oksana V, Degtyaryova, Ksenia O, Deyev, Igor E, Bezuglov, Vladimir V

“…GPR55 is a non-canonical cannabinoid receptor, important for cancer proliferation. Depending on the ligand, it induces either cell proliferation or death. The…”
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The Interaction of the Endocannabinoid Anandamide and Paracannabinoid Lysophosphatidylinositol during Cell Death Induction in Human Breast Cancer Cells by Akimov, Mikhail G, Gretskaya, Natalia M, Gorbacheva, Evgenia I, Khadour, Nisreen, Chernavskaya, Valeria S, Sherstyanykh, Galina D, Kovaleko, Tatiana F, Fomina-Ageeva, Elena V, Bezuglov, Vladimir V

“…Endocannabinoid anandamide (AEA) and paracannabinoid lysophosphatidylinositol (LPI) play a significant role in cancer cell proliferation regulation. While…”
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Neuroprotective properties of endocannabinoids N-arachidonoyl dopamine and N-docosahexaenoyl dopamine examined in neuronal precursors derived from human pluripotent stem cells by Novosadova, E. V., Arsenyeva, E. L., Manuilova, E. S., Khaspekov, L. G., Bobrov, M. Yu, Bezuglov, V. V., Illarioshkin, S. N., Grivennikov, I. A.

“…Neuroprotective properties of endocannabinoids N-arachidonoyl dopamine (NADA) and N-docosahexaenoyl dopamine (DHDA) were examined in neuronal precursor cells…”
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A New Method for the Visualization of Living Dopaminergic Neurons and Prospects for Using It to Develop Targeted Drug Delivery to These Cells by Blokhin, Victor, Lavrova, Alina V, Surkov, Sergey A, Mingazov, Eduard R, Gretskaya, Natalia M, Bezuglov, Vladimir V, Ugrumov, Michael V

“…This is the first study aiming to develop a method for the long-term visualization of living nigrostriatal dopaminergic neurons using…”
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GPR55 Receptor Activation by the N -Acyl Dopamine Family Lipids Induces Apoptosis in Cancer Cells via the Nitric Oxide Synthase (nNOS) Over-Stimulation by Akimov, Mikhail G, Gamisonia, Alina M, Dudina, Polina V, Gretskaya, Natalia M, Gaydaryova, Anastasia A, Kuznetsov, Andrey S, Zinchenko, Galina N, Bezuglov, Vladimir V

“…GPR55 is a GPCR of the non-CB1/CB2 cannabinoid receptor family, which is activated by lysophosphatidylinositol (LPI) and stimulates the proliferation of cancer…”
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Early-life N-arachidonoyl-dopamine exposure increases antioxidant capacity of the brain tissues and reduces functional deficits after neonatal hypoxia in rats by Sukhanova, Iu.A., Sebentsova, E.A., Khukhareva, D.D., Vysokikh, M.Yu, Bezuglov, V.V., Bobrov, M.Yu, Levitskaya, N.G.

“…•Acute neonatal hypoxia resulted in upregulation of HIF1-α, GPx2 and GPx4 genes expression in rat brains.•Acute neonatal hypoxia led to delay in sensorimotor…”
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Study of the Antiviral Activity of Adamantane-Containing Chemical Compounds by I. I. LYUBIMOV, E. I. ISAEVA, E. N. VETROVA, A. V. LAVROVA, N. M. GRETSKAYA, I. V. SERKOV, V. V. BEZUGLOV, G. A. GALEGOV

“…Influenza and coronavirus infections are especially dangerous due to being capable of causing pandemics and clinical complications in the nervous and…”
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Role of Oxidative Stress in the Etiology of Parkinson’s Disease: Advanced Therapeutic Products by Lavrova, A. V., Gretskaya, N. M., Bezuglov, V. V.

“…The etiology of Parkinson’s disease (PD) is not exactly known. However, oxidative stress was identified as a key factor that initiates and accelerates…”
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N-Acyl Dopamines Induce Apoptosis in Endometrial Stromal Cells from Patients with Endometriosis by Gamisonia, Alina M., Yushina, Marina N., Fedorova-Gogolina, Irina A., Akimov, Mikhail G., Eldarov, Chupalav M., Pavlovich, Stanislav V., Bezuglov, Vladimir V., Gretskaya, Natalia M., Sukhikh, Gennady T., Bobrov, Mikhail Yu

“…Endometriosis is characterized by the formation and development of endometrial tissues outside the uterus, based on an imbalance between proliferation and cell…”
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In Vivo Targeted Metabolomic Profiling of Prostanit, a Novel Anti-PAD NO-Donating Alprostadil-Based Drug by Shestakova, Ksenia M, Moskaleva, Natalia E, Mesonzhnik, Natalia V, Kukharenko, Alexey V, Serkov, Igor V, Lyubimov, Igor I, Fomina-Ageeva, Elena V, Bezuglov, Vladimir V, Akimov, Mikhail G, Appolonova, Svetlana A

“…Prostanit is a novel drug developed for the treatment of peripheral arterial diseases. It consists of a prostaglandin E (PGE ) moiety with two nitric oxide…”
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N-acyl-dopamines: Novel synthetic CB1 cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo by Bisogno, T, Melck, D, Bobrov MYu, Gretskaya, N M, Bezuglov, V V, De Petrocellis, L, Di Marzo, V

“…We reported previously that synthetic amides of polyunsaturated fatty acids with bioactive amines can result in substances that interact with proteins of the…”
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Physiological and Pathological Role of TRPV1, TRPV2 and TRPV4 Channels in Heart by Gorbunov, Alexandr S, Maslov, Leonid N, Jaggi, Amteshwar S, Singh, Nirmal, De Petrocellis, Luciano, Boshchenko, Alla A, Roohbakhsh, Ali, Bezuglov, Vladimir V, Oeltgen, Peter R

“…Transient receptor potential vanilloid channel 2 (TRPV2) is required for normal cardiac contractility. The stimulation of TRPV1 in isolated cardiomyocytes can…”
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Power System for Industrial ILU-Type Electron Accelerators by Bezuglov, V. V., Bryazgin, A. A., Vlasov, A. Yu, Voronin, L. A., Drogunov, E. V., Korobeinikov, M. V., Maksimov, S. A., Nekhaev, V. E., Pak, A. V., Radchenko, V. M., Sidorov, A. V., Tkachenko, V. O., Shtarklev, E. A.

“…The device and principle of operation of the pulse modulator, which is the power-supply system for the ILU series accelerators, as well as some features that…”
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A Novel Fluorescent Analog of the Dopamine Reuptake Inhibitor GBR12909 by Lavrova, A. V., Gretskaya, N. M., Akimov, M. G., Bezuglov, V. V.

“…Dopamine transporter is a transmembrane protein associated with regulation of dopaminergic signal transmission by dopamine reuptake from the synaptic cleft…”
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Selective Action of N-Arachidonoyl Dopamine on Viability and Proliferation of Stromal Cells from Eutopic and Ectopic Endometrium by Ashba, A. M., Yushina, M. N., Fedorova-Gogolina, I. A., Gretskaya, N. M., Bezuglov, V. V., Melkumyan, A. G., Pavlovich, S. V., Bobrov, M. Yu

“…We performed a comparative study of the cytotoxic effect of endocannabinoid N-arachidonoyl dopamine (AA-DA) on cultured stromal cells of ectopic and eutopic…”
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Development of a Three-Modulator Pulse Power Supply System for the ILU-14 Electron Accelerator by Bezuglov, V. V., Bryazgin, A. A., Vlasov, A. Yu, Voronin, L. A., Kokin, E. N., Korobeinikov, M. V., Sidorov, A. V., Tkachenko, V. O., Shtarklev, E. A.

“…The control and protection systems that have made it possible to create a unique 3-modulator pulse power supply for the ILU-14 accelerator are described…”
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N-acyl dopamines induce apoptosis in PC12 cell line via the GPR55 receptor activation by Akimov, M. G., Ashba, A. M., Gretskaya, N. M., Bezuglov, V. V.

“…Dopamine amides of arachidonic, docosahexaenoic, and oleic acids were found to induce apoptosis in PC12 cells, which was blocked exclusively by antagonists and…”
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A Pulsed Power Supply for Accelerators of the ILU Series Based on Capacitive Storage by Bezuglov, V. V., Bryazgin, A. A., Vlasov, A. Yu, Voronin, L. A., Korobeinikov, M. V., Maksimov, S. A., Pak, A. V., Radchenko, V. M., Sidorov, A. V., Tkachenko, V. O., Shtarklev, E. A.

“…—A pulsed power supply based on capacitive storage with a partial discharge for high-frequency pulsed linear electron accelerators of the ILU type is…”
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Neuroprotective and Antioxidant Activity of Arachidonoyl Choline, Its Bis-Quaternized Analogues and Other Acylcholines by Akimov, M. G., Dudina, P. V., Fomina-Ageeva, E. V., Gretskaya, N. M., Bosaya, A. A., Rudakova, E. V., Makhaeva, G. F., Kagarlitsky, G. O., Eremin, S. A., Tsetlin, V. I., Bezuglov, V. V.

“…The antioxidant activity and protective effect in the toxicity model of H 2 O 2 were studied for arachidonic (AA-CHOL), docosahexaenoic (DHA-CHOL), linoleic…”
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