Search Results - "Bezerra, Marcos André C"

DNA polymorphisms at the BCL11A, HBS1L-MYB, and β-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease by Lettre, Guillaume, Sankaran, Vijay G, Bezerra, Marcos André C, Araújo, Aderson S, Uda, Manuela, Sanna, Serena, Cao, Antonio, Schlessinger, David, Costa, Fernando F, Hirschhorn, Joel N, Orkin, Stuart H

“…Sickle cell disease (SCD) is a debilitating monogenic blood disorder with a highly variable phenotype characterized by severe pain crises, acute clinical…”
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BMP6 and VDR gene polymorphisms are associated with osteonecrosis in a sickle cell anaemia cohort by Arcanjo, Gabriela S., Souza, Mariana B., Domingos, Igor F., Pereira‐Martins, Diego A., Falcão, Diego A., Batista, Jessica V., Hatzlhofer, Betania L., Diniz, Madi V., Silva, Alexsandro P., Guaraná, Werbson L., Hazin, Manuela F., Araujo, Aderson S., Cunha, Anderson F., Saad, Sara O., Costa, Fernando F., Lucena‐Araujo, Antonio R., Bezerra, Marcos André C.

“…Summary The occurrence and severity of osteonecrosis in sickle cell anaemia (SCA) vary due to risk factors, including genetic modifiers. Bone morphogenetic…”
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Global gene expression reveals an increase of HMGB1 and APEX1 proteins and their involvement in oxidative stress, apoptosis and inflammation pathways among beta‐thalassaemia intermedia and major phenotypes by Maia de Oliveira da Silva, João Pedro, Brugnerotto, Ana Flávia, S. Romanello, Karen, K. L. Teixeira, Karina, Lanaro, Carolina, S. Duarte, Adriana, G. L. Costa, Gustavo, da Silva Araújo, Aderson, C. Bezerra, Marcos André, de Farias Domingos, Igor, Pereira Martins, Diego A., Malavazi, Iran, F. Costa, Fernando, Cunha, Anderson F.

“…Summary Beta‐thalassaemia (BT) is classified according to blood transfusion requirement as minor (BTMi), intermedia (BTI) and major (BTM). BTM is the most…”
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Neutrophil extracellular trap regulators in sickle cell disease: Modulation of gene expression of PADI4, neutrophil elastase, and myeloperoxidase during vaso‐occlusive crisis by Hounkpe, Bidossessi Wilfried, Chenou, Francine, Domingos, Igor de Farias, Cardoso, Evilazio Cunha, Costa Sobreira, Marcondes José de Vasconcelos, Araujo, Aderson S., Lucena‐Araújo, Antonio Roberto, da Silva Neto, Pedro Vieira, Malheiro, Adriana, Fraiji, Nelson Abrahim, Costa, Fernando Ferreira, Bezerra, Marcos André C., Santos, Magnun Nueldo Nunes, De Paula, Erich Vinicius

“…Recent evidence suggests that generation of neutrophil extracellular traps (NETosis), one of the components of immunothrombosis, is associated with the…”
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Global analysis of erythroid cells redox status reveals the involvement of Prdx1 and Prdx2 in the severity of beta thalassemia by Romanello, Karen S, Teixeira, Karina K L, Silva, João Pedro M O, Nagamatsu, Sheila T, Bezerra, Marcos André C, Domingos, Igor F, Martins, Diego A P, Araujo, Aderson S, Lanaro, Carolina, Breyer, Carlos A, Ferreira, Regiane A, Franco-Penteado, Carla, Costa, Fernando F, Malavazi, Iran, Netto, Luis E S, de Oliveira, Marcos A, Cunha, Anderson F

“…β-thalassemia is a worldwide distributed monogenic red cell disorder, characterized by an absent or reduced beta globin chain synthesis. The unbalance of…”
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Women with TT genotype for eNOS gene are more responsive in lowering blood pressure in response to exercise by Sponton, Carlos H G, Rezende, Tiago M, Mallagrino, Pamella A, Franco-Penteado, Carla F, Bezerra, Marcos André C, Zanesco, Angelina

“…The aim of this study was to investigate whether -786T>C endothelial nitric oxide synthase (eNOS) gene polymorphism might influence the effect of long-term…”
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MTHFR polymorphic variant C677T is associated to vascular complications in sickle-cell disease by Hatzlhofer, Betânia L D, Bezerra, Marcos André C, Santos, Magnun N N, Albuquerque, Dulcinéia M, Freitas, Elizabete M, Costa, Fernando F, Araújo, Aderson S, Muniz, Maria Tereza C

“…Vaso-occlusion is a determinant for most signs and symptoms of sickle-cell anemia (SCA). The mechanisms involved in the pathogenesis of vascular complications…”
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Molecular Variations Linked to the Grouping of β- and α-Globin Genes in Neonatal Patients with Sickle Cell Disease in the State of Pernambuco, Brazil by Bezerra, Marcos André C., Santos, Magnun N.N., Araújo, Aderson S., Gomes, Yara M., Abath, Frederico G.C., Bandeira, Flavia M.G.C.

“…Various factors have been described as phenotypic modulators of sickle cell disease, such as levels of fetal hemoglobin (Hb F), presence of α-thalassemia…”
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Inflammatory Mediators Are Increased in Leukocytes of IVS-I-6 (T→C) Homozygous β-Thalassemia Intermedia by Bezerra, Marcos André C, Franco-Penteado, Carla Fernanda, Lanaro, Carolina, Mello, Mariana R.B., Gambero, Sheley, Albuquerque, Dulcinéia M, Fertrin, Kleber Yotsumoto, Saad, Sara T.O, Araujo, Aderson S, Costa, Fernando Ferreira

“…Abstract 4068 Poster Board III-1003 Thalassemia is characterized by chronic inflammatory state and inflammation may play an important role in the pathogenesis…”
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Inhibition of Phosphodiesterase 9A (PDE9A) Significantly Reduces Cytokine-Stimulated Adhesion of Neutrophils From Sickle Cell Disease Individuals, in Vitro, but Not Red Cell Adhesion by Miguel, Lediana I, Almeida, Camila B., Franco-Penteado, Carla F, Bezerra, Marcos André C, Traina, Fabiola, Dominical, Venina M, Araujo, Aderson S, Saad, Sara T.O., Costa, Fernando F., Conran, Nicola

“…Abstract 1520 Poster Board I-543 The adhesion of both red and white cells to the vessel walls of the microcirculation initiates vaso-occlusion in sickle cell…”
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Upregulation of the Anti-Apoptotic Protein, Survivin, in Hematopoietic Cells in Sickle Cell Anemia and Effects of Hydroxyurea Therapy by Lanaro, Carolina, Franco-Penteado, Carla Fernanda, Mello, Mariana R.B., Fertrin, Kleber Yotsumoto, Bezerra, Marcos André C, Albuquerque, Dulcinéia M., Conran, Nicola, Saad, Sara T.O., Araujo, Aderson S., Costa, Fernando F.

“…Abstract 1532 Poster Board I-555 Survivin (BIRC5) is a member of the inhibitors of apoptosis family implicated in both prevention of cell death and control of…”
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Follow-up of children with hemoglobinopathies diagnosed by the Brazilian Neonatal Screening Program in the State of Pernambuco by Soares, Ana Caroline Novaes, Samico, Isabella Chagas, Araújo, Aderson Silva, Bezerra, Marcos André C., Hatzlhofer, Betânia Lucena Domingues

“…To determine the geographical distribution of hemoglobinopathies in the State of Pernambuco, to characterize the children with these diseases and to describe…”
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Effect of High Levels of Growth Differentiation Factor 15 (GDF15) On Hepcidin Expression in Monocytes of β-Thalassemia Intermedia Patients by Fertrin, Kleber Yotsumoto, Lanaro, Carolina, Franco-Penteado, Carla Fernanda, Albuquerque, Dulcinéia M, Mello, Mariana R.B., Bezerra, Marcos André C, Domingues, Betania Lucena Borges Tavares, Saad, Sara T.O, Araujo, Aderson S, Costa, Fernando Ferreira

“…Abstract 4061 Poster Board III-996 Ineffective erythropoiesis in thalassemia has been associated with inappropriate suppression of hepatic synthesis of the key…”
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Family screening for HBBS gene and detection of new cases of sickle cell trait in Northeastern Brazil by Bandeira, Flavia Miranda Gomes C, Santos, Magnun Nueldo Nunes, Bezerra, Marcos André M, Gomes, Yara M, Araujo, Aderson Silva, Braga, Maria Cynthia, Souza, Wayner Vieira, Abath, Frederico G C

“…To estimate the additional number of affected individuals based on the prevalence of sickle-cell syndromes among relatives of index cases. Cross-sectional…”
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Prevalence of dyslipidemia in middle-aged adults with NOS3 gene polymorphism and low cardiorespiratory fitness by Malagrino, Pamella A, Sponton, Carlos H G, Esposti, Rodrigo D, Franco-Penteado, Carla F, Fernandes, Romulo A, Bezerra, Marcos André C, Albuquerque, Dulcinéia M, Rodovalho, Cynara M, Bacci, Maurício, Zanesco, Angelina

“…To evaluate the influence of the interaction between endothelial nitric oxide synthase gene (NOS3) polymorphisms at positions -786T>C, Glu298Asp and intron…”
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DNA polymorphisms at the BCL11A, HBS1L-MYB, and [beta]-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease by Lettre, Guillaume, Sankaran, Vijay G, Bezerra, Marcos André C, Araújo, Aderson S, Uda, Manuela, Sanna, Serena, Cao, Antonio, Schlessinger, David, Costa, Fernando F, Hirschhorn, Joel N, Orkin, Stuart H

“…Sickle cell disease (SCD) is a debilitating monogenic blood disorder with a highly variable phenotype characterized by severe pain crises, acute clinical…”
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DNA polymorphisms at the BCL11A, HBS1L-MYB, and b-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease by Lettre, Guillaume, Sankaran, Vijay G, Bezerra, Marcos Andre C, Araujo, Aderson S, Uda, Manuela, Sanna, Serena, Cao, Antonio, Schlessinger, David, Costa, Fernando F, Hirschhorn, Joel N, Orkin, Stuart H

“…Sickle cell disease (SCD) is a debilitating monogenic blood disorder with a highly variable phenotype characterized by severe pain crises, acute clinical…”
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Prevalência de dislipidemia em adultos de meia-idade com polimorfismo do gene NOS3 e baixa aptidão cardiorrespiratória by Malagrino, Pamella A., Sponton, Carlos H. G., Esposti, Rodrigo D., Franco-Penteado, Carla F., Fernandes, Romulo A., Bezerra, Marcos André C., Albuquerque, Dulcinéia M., Rodovalho, Cynara M., Bacci, Maurício, Zanesco, Angelina

“…OBJETIVO: Analisar a influência da associação dos polimorfismos do gene da sintase do óxido nítrico endotelial (NOS3) para as posições -786T>C, Glu298Asp e…”
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Prevalência de dislipidemia em adultos de meia-idade com polimorfismo do gene NOS3 e baixa aptidão cardiorrespiratória by Malagrino, Pamella A., Sponton, Carlos H. G., Esposti, Rodrigo D., Franco-Penteado, Carla F., Fernandes, Romulo A., Bezerra, Marcos André C., Albuquerque, Dulcinéia M., Rodovalho, Cynara M., Bacci, Maurício, Zanesco, Angelina

“…OBJETIVO: Analisar a influência da associação dos polimorfismos do gene da sintase do óxido nítrico endotelial (NOS3) para as posições -786T>C, Glu298Asp e…”
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