Search Results - "Bezek, S"

Controversy of free radical hypothesis: reactive oxygen species--cause or consequence of tissue injury? by Juránek, I, Bezek, S

“…For a decade or two, the hypothesis of causality of various disorders by reactive oxygen species (ROS), due to their potentially harmful effect towards…”
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Synthetic Pyridoindole and Rutin Affect Upregulation of Endothelial Nitric Oxide Synthase and Heart Function in Rats Fed a High-Fat-Fructose Diet by Salvaras, L, Kovacic, T, Janega, P, Liptak, B, Sasvariova, M, Michalikova, D, Tyukos Kaprinay, B, Bezek, S, Sotnikova, R, Knezl, V, Sankovicova, T, Gasparova, Z

“…Metabolic syndrome (MetS) belongs to the serious health complications expanding in cardiovascular diseases, obesity, insulin resistance, and hyperglycemia. In…”
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Effect of high-fat-fructose diet on synaptic plasticity in hippocampus and lipid profile of blood serum of rat: pharmacological possibilities of affecting risk factors by Micháliková, D., Kaprinay, B. Tyukos, Lipták, B., Švík, K., Slovák, L., Sotníková, R., Bezek, Š., Gáspárová, Z.

“…Abstract The aim of this study was to determine pharmacological possibilities of influencing the risk factors of metabolic syndrome (MetS)…”
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Neglected Infections of Poverty in Texas and the Rest of the United States: Management and Treatment Options by Barry, M A, Bezek, S, Serpa, J A, Hotez, P J, Woc-Colburn, L

“…In the poorest regions of the United States, especially along the Gulf Coast and in South Texas, are a group of endemic parasitic and related infections known…”
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42 Acute Care and Injury Prevention Longitudinal Ambulatory Care Experience: A Curricular Innovation by Bezek, S, Hoxhaj, S, Kapur, B, Cao, D, Finn, R

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Role of reactive oxygen and nitrogen species in etiopathogenesis of rheumatoid arthritis by Bauerová, K, Bezek, A

“…Rheumatoid arthritis (RA) is a chronic disease affecting up to 3% of the population in most countries. The causes of RA have not been completely elucidated…”
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316 Gender and the State of Professionalism Between Physicians and Nurses in the Emergency Department by Suh, M., Huynh, P., Garzon, M., Thomas, Y., Buehler, G., Bezek, S., Jonathan, Garcia, Stephanie LaBuz, Navdeep Sekhon, Anita Chary/Baylor College of Medicine, Houston, Texas, US

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Effects of ionizing radiation on the blood brain barrier permeability to pharmacologically active substances by Trnovec, T, Kállay, Z, Bezek, S

“…Ionizing radiation can impair the integrity of the blood brain barrier (BBB). Data on early and late damage after brain irradiation are usually reported…”
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Role of hepatovasculature in warm ischaemia-reperfusion injury of rat liver by Kukan, M, Bezek, S, Trnovec, T

“…Liver haemodynamics were studied after warm (37 degrees C) ischaemia of isolated rat livers for periods of 30 s (Group 1), 30 min (Group 2), and 60 min (Group…”
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Biosynthesis and isolation of an ether glucuronide of azidothymidine from rat bile by thin-layer chromatography by KUKAN, M, HRICOVINI, M, BEZEK, S

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Metabolic disposition of tacrine in primary suspensions of rat hepatocyte and in single-pass perfused liver: in vitro/in vivo comparisons by Kukan, M, Bezek, S, Pool, W F, Woolf, T F

“…1. Incubations of tacrine (1,2,3,4-tetrahydro-9-acridinamine monohydrochloride monohydrate, THA) with a primary suspension of rat hepatocytes for 2 min…”
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Uptake, reflux, and excretion of bromosulfophthalein in ischaemia-reperfusion injury of rat liver by Kukan, M, Bezek, S, Trnovec, T

“…The uptake, reflux and excretion of bromosulfophthalein (BSP) were studied on a model of total warm ischaemia for 30 min (group 1) or 60 min (group 2) followed…”
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The effect of cytochromes P4501A induction and inhibition on the disposition of the cognition activator tacrine in rat hepatic preparations by Bezek, S, Kukan, M, Pool, W F, Woolf, T F

“…1. The disposition of tacrine 1,2,3,4-tetrahydro-9-acridinamine monohydrochloride monohydrate (THA, Cognex), was studied using livers obtained from control,…”
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Bioavailability and pharmacokinetic studies in the development of an oral formulation of stobadine dipalmitate by BAUEROVA, K, BOHOV, P, DURISOVA, M, BEZEK, S

“…The pyridoindole stobadine is a novel drug with antioxidant and cardioprotective properties. The objective of this study was to compare the bioavailability and…”
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Hepatic uptake and metabolism of pentacaine: a study with microsomes, hepatocytes and perfused livers of rats by Stefek, M, Bezek, S

“…The uptake and metabolism of pentacaine, a novel carbanilate local anaesthetic agent, were studied using different rat-liver preparations. Pentacaine, added to…”
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Characterization of nonlinear elimination of the xanthine-related drug ethimizol in 3-methylcholanthrene-induced rat liver by the "parallel-tube" model by Kukan, M, Woolf, T F, Melus, M, Bezek, S

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Disposition of ethimizol, a xanthine-related nootropic drug, in perfused rat liver and isolated hepatocytes by Bezek, S, Kukan, M, Kállay, Z, Trnovec, T, Stefek, M, Piotrovskiy, L B

“…Ethimizol, 4,5-di(methylcarbamoyl)-1-ethyl-imidazole, was metabolized into at least six metabolites in an isolated perfused rat liver preparation. Based on TLC…”
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The effect of enzyme induction and inhibition on the disposition of the xanthine-related nootropic drug ethimizol in perfused liver and hepatocytes of rats by Kukan, M, Bezek, S, Stefek, M, Trnovec, T, Durisová, M, Piotrovskiy, L B

“…The once-through perfused (18 ml/min) rat liver preparations from vehicle-, phenobarbital (PB)-, and 3-methylcholanthrene (3-MC)-treated rats were used for the…”
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Selective uptake of the anticancer drug bendamustine by liver and kidney tissues following its intravenous administration to mice by Bezek, S, Kukan, M, Scasnár, V, Lukácsová, M, Trnovec, T

“…Distribution of 14C-bendamustine following intravenous (i.v.) administration to mice was examined by whole body autoradiographic (WBAR) and quantitative…”
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Hepatobiliary elimination of bendamustin (Cytostasan) in rats by Bezek, S, Scasnár, V, Trnovec, T, Grupe, R

“…Biliary excretion of bendamustin (Cytostasan, 5-[bis(2-chloroethyl)amino]-i-methylbenzimidazole-2-butyric acid; 1) and its metabolites was studied in rats…”
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