Search Results - "Bezborodkina, N N"

Pharmacotherapy for Non-Alcoholic Fatty Liver Disease: Emerging Targets and Drug Candidates by Prikhodko, Veronika A, Bezborodkina, Natalia N, Okovityi, Sergey V

“…Non-alcoholic fatty liver disease (NAFLD), or metabolic (dysfunction)-associated fatty liver disease (MAFLD), is characterized by high global incidence and…”
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The role of cellular polyploidy in the regeneration of the cirrhotic liver in rats and humans by Bezborodkina, Natalia N, Brodsky, Vsevolod Ya, Kudryavtsev, Boris N

“…Polyploidy is a condition in which a cell has multiple diploid sets of chromosomes. Two forms of polyploidy are known. One of them, generative polyploidy, is…”
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Dynamics of the Glycogen β-Particle Number in Rat Hepatocytes during Glucose Refeeding by Bezborodkina, Natalia N., Stepanov, Andrei V., Vorobev, Mikhail L., Stein, Grigory I., Okovityi, Sergey V., Kudryavtsev, Boris N.

“…Glycogen is an easily accessible source of energy for various processes. In hepatocytes, it can be found in the form of individual molecules (β-particles) and…”
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Postprandial Glycogen Content Is Increased in the Hepatocytes of Human and Rat Cirrhotic Liver by Bezborodkina, Natalia N, Okovityi, Sergey V, Kudryavtsev, Boris N

“…Chronic hepatitises of various etiologies are widespread liver diseases in humans. Their final stage, liver cirrhosis (LC), is considered to be one of the main…”
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Spatial Structure of Glycogen Molecules in Cells by Bezborodkina, N. N., Chestnova, A. Yu, Vorobev, M. L., Kudryavtsev, B. N.

“…Glycogen is a strongly branched polymer of α-D-glucose, with glucose residues in the linear chains linked by 1→4-bonds (~93% of the total number of bonds) and…”
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Dynamics of pro- and macroglycogen content in hepatocytes of normal and cirrhotic rat liver at different stages of glycogenesis by Chestnova, A Iu, Bezborodkina, N N, Matiukhina, N M, Kudriavtsev, B N

“…The content and structure of glycogen in hepatocytes of normal and cirrhotic rat liver has been studied at definite time intervals after the administration of…”
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Cytochemical analysis of spatial structure of glycogen molecules in rat hepatocytes by Bezborodkina, Natalia N, Stepanov, Andrei V, Vorobev, Mikhail L, Chestnova, Anna Yu, Stein, Grigory I, Kudryavtsev, Boris N

“…•Glycogen content change is accompanied by changes in the structure of its molecules.•The external tier of β-particle is never completely filled with…”
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Heterogeneity of Left Ventricular Cardiomyocytes from Rat Heart by Baidyuk, E. V., Bitkova, E. A., Bezborodkina, N. N., Karpov, A. A., Korshak, O. V., Sakuta, G. A., Kudryavtsev, B. N.

“…Contractile cardiomyocytes in various parts of the heart differ in shape, size, ploidy, and other parameters. However, it is not known whether their population…”
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Glycogen content in hepatocytes is related with their size in normal rat liver but not in cirrhotic one by Bezborodkina, Natalia N., Chestnova, Anna Yu, Vorobev, Mikhail L., Kudryavtsev, Boris N.

“…Background & Aims: Hepatocytes differ from one another by the degree of the ploidy, size, position in the liver lobule, and level of the DNA‐synthetic…”
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On reprogramming of tumor cells metabolism: detection of glycogen in the cell lines of hepatocellular origin with various degrees of dedifferentiation by Teryukova, Natalya P., Malkova, Victoria V., Sakhenberg, Elena I., Ivanov, Vadim A., Bezborodkina, Natalia N., Snopov, Sergei A.

“…The reprogramming of cancer cells includes shifts in glucose and glycogen metabolism. The aim of our work was to check the ability of forming glycogen grains…”
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Application of Schiff's reagents with various spectral characteristics to determine the content of labile and stable glycogen fractions in isolated hepatocytes by Bezborodkina, N N, Kirshina, E I, Mushinskaia, E V, Kudraivtsev, B N

“…The dynamics of the total glycogen accumulation, its labile and stable fraction contents were studied in hepatocytes after administration of 30 % glucose to…”
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Cell Polyploidy. Cardiac Muscle. Liver. Ontogenesis and Regeneration by Brodsky, V. Ya, Kudryavtsev, B. N., Bezborodkina, N. N.

“…Cell (somatic) polyploidy is a general biological phenomenon characteristic of unicellular and multicellular animals and plants. In mammals, polyploid cells…”
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Activity of glycogen synthase and glycogen phosphorylase in normal and cirrhotic rat liver during glycogen synthesis from glucose or fructose by Bezborodkina, Natalia N., Chestnova, Anna Yu, Okovity, Sergey V., Kudryavtsev, Boris N.

“…Cirrhotic patients often demonstrate glucose intolerance, one of the possible causes being a decreased glycogen-synthesizing capacity of the liver. At the same…”
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Metabolic heterogeneity of glycogen in hepatocytes of patients with liver cirrhosis : the glycogen of the liver lobule zones in cirrhosis by KUDRYAVTSEVA, Margarita V, BEZBORODKINA, Natalia N, OKOVITY, Sergey V, KUDRYAVTSEV, Boris N

“…The concentrations of total glycogen (TG) and its labile (LF) and stable (SF) fractions were determined in hepatocytes of portal and central zones of the…”
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Metformin normalizes the structural changes in glycogen preceding prediabetes in mice overexpressing neuropeptide Y in noradrenergic neurons by Ailanen, Liisa, Bezborodkina, Natalia N., Virtanen, Laura, Ruohonen, Suvi T., Malova, Anastasia V., Okovityi, Sergey V., Chistyakova, Elizaveta Y., Savontaus, Eriika

“…Hepatic insulin resistance and increased gluconeogenesis are known therapeutic targets of metformin, but the role of hepatic glycogen in the pathogenesis of…”
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Glycogen-forming function of hepatocytes in cirrhotically altered rat liver after treatment with chorionic gonadotropin by Kudryavtseva, Margarita V., Bezborodkina, Natalia N., Kudryavtsev, Boris N.

“…Using cytofluorimetric and biochemical studies on serial supravital liver punctate biopsies, effects of chorionic gonadotropin (CG) on recovery of hepatocyte…”
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Effects of the 2-ethylthiobenzimidazole hydrobromide (bemithyl) on carbohydrate metabolism in cirrhotic rat liver by Kudryavtseva, Margarita V., Bezborodkina, Natalia N., Okovity, Sergey V., Kudryavtsey, Boris N.

“…The effect of the actoprotector bemithyl (2-ethylthiobenzimidazole hydrobromide) on the content of glycogen and activities of glycogen synthase, glycogen…”
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Hepatocytes of cirrhotic rat liver accumulate glycogen more slowly than normal ones by Bezborodkina, Natalia N., Okovity, Sergey V., Chestnova, Anna Yu, Kudryavtsev, Boris N.

“…Purpose To investigate the accumulation of glycogen in cirrhotic rat liver at several time intervals after per os administration of glucose to fasted animals…”
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Glycogen-forming function of hepatocytes in the rat regenerating cirrhotic liver after a partial hepatectomy by Kudryavtseva, M.V., Emelyanov, A.V., Sakuta, G.A., Bezborodkina, N.N., Kudryavtsev, B.N.

“…Rat liver punctate biopsies were used for cytofluorimetric determinations of the content of glycogen and its fractions in hepatocytes, and also for…”
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Dynamics of proglycogen and macroglycogen in hepatocytes of normal and cirrhotic rat liver at various stages of glycogenesis by Chestnova, A. Yu, Bezborodkina, N. N., Matyukhina, N. M., Kudryavtsev, B. N.

“…The content and structure of glycogen in hepatocytes of normal and cirrhotic rat liver were examined at different time intervals after glucose administration…”
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