Search Results - "Bezbaruah, Babul Kumar"

Multiple facets of poly(ADP-ribose) polymerase-1 in neurological diseases by Sriram, Chandra Shaker, Jangra, Ashok, Madhana, Rajaram Mohanrao, Gurjar, Satendra Singh, Mohan, Pritam, Bezbaruah, Babul Kumar

“…PARP-1 activation is associated in DNA repair, cell death and inflammation. Since oxidative stress induced robust DNA damage and wide spread inflammatory…”
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Binge alcohol consumption exacerbates high-fat diet-induced neurobehavioral anomalies: Possible underlying mechanisms by Singh, Tavleen, Kwatra, Mohit, Kushwah, Pawan, Pant, Rajat, Bezbaruah, Babul Kumar, Jangra, Ashok

“…The current study aimed to validate the mice model of alcohol (ALC), high-fat diet (HFD), and HFD + ALC combination affecting neurobehavioral and neurochemical…”
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Edaravone abrogates LPS-induced behavioral anomalies, neuroinflammation and PARP-1 by Sriram, Chandra Shaker, Jangra, Ashok, Gurjar, Satendra Singh, Mohan, Pritam, Bezbaruah, Babul Kumar

“…Abstract Poly(ADP-ribose) polymerase-1 (PARP-1) is a DNA nick-sensor enzyme that functions at the center of cellular stress response and affects the immune…”
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Piperine Augments the Protective Effect of Curcumin Against Lipopolysaccharide-Induced Neurobehavioral and Neurochemical Deficits in Mice by Jangra, Ashok, Kwatra, Mohit, Singh, Tavleen, Pant, Rajat, Kushwah, Pawan, Sharma, Yogita, Saroha, Babita, Datusalia, Ashok Kumar, Bezbaruah, Babul Kumar

“…The aim of the present study was to investigate the protective effects of curcumin alone and in combination with piperine against lipopolysaccharide…”
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Cognitive deficits induced by combined exposure of stress and alcohol mediated through oxidative stress-PARP pathway in the hippocampus by Pant, Rajat, Jangra, Ashok, Kwatra, Mohit, Singh, Tavleen, Kushwah, Pawan, Bezbaruah, Babul Kumar, Gurjar, Satendra Singh, Phukan, Swopna

“…•Restraint stress increases alcohol consumption in mice.•Combined exposure of alcohol and stress aggravates memory deficits.•Oxidative stress-PARP cascade gets…”
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Poly (ADP-ribose) polymerase-1 inhibitor, 3-aminobenzamide pretreatment ameliorates lipopolysaccharide-induced neurobehavioral and neurochemical anomalies in mice by Sriram, Chandra Shaker, Jangra, Ashok, Gurjar, Satendra Singh, Hussain, Md Iftikar, Borah, Probodh, Lahkar, Mangala, Mohan, Pritam, Bezbaruah, Babul Kumar

“…Poly (ADP-ribose) polymerase-1 (PARP-1) functions at the center of cellular stress and sways the immune system at several key points, thus modulates…”
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Targeting poly(ADP-ribose)polymerase1 in neurological diseases: A promising trove for new pharmacological interventions to enter clinical translation by Sriram, Chandra Shekhar, Jangra, Ashok, Kasala, Eshvendar Reddy, Bodduluru, Lakshmi Narendra, Bezbaruah, Babul Kumar

“…•Short introduction on poly(ADP-ribose)polymerase (PARP1) and its structural features.•Overview of PARP1 activity.•Succinct outline of various implications of…”
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Prescribing pattern of analgesics in orthopedic in-patient department at tertiary care hospital in Guwahati, Assam, Northeast India by Choudhury, Dwijen, Bezbaruah, Babul

“…Objectives: The aim of this study is to evaluate the prescribing pattern of analgesics and analyze the rational use of analgesic in orthopedic in-patient…”
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Epigenetic Modifications, Alcoholic Brain and Potential Drug Targets by Jangra, Ashok, Sriram, Chandra Shaker, Pandey, Suryanarayan, Choubey, Priyansha, Rajput, Prabha, Saroha, Babita, Bezbaruah, Babul Kumar, Lahkar, Mangala

“…Acute and chronic alcohol exposure evidently influences epigenetic changes, both transiently and permanently, and these changes in turn influence a variety of…”
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Alternative mechanisms of inhibiting activity of poly (ADP-ribose) polymerase-1 by Sriram, Chandra Shaker, Jangra, Ashok, Bezbaruah, Babul Kumar, V, Athira K, Sykam, Shivaji

“…Poly ADP-ribose polymerase (PARP-1), a DNA nick-sensor enzyme, is an abundant nuclear protein. Upon sensing DNA breaks, PARP-1 gets activated and cleaves NAD…”
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