Greater intake of the MEDI diet is associated with better cognitive trajectory in older adults with type 2 diabetes

To determine associations of three dietary patterns (Mediterranean (MEDI) diet, the Dietary Approaches to Stop Hypertension (DASH) diet and the Mediterranean- DASH Intervention for Neurodegenerative Delay (MIND) diet) with cognitive decline in older adults with type 2 diabetes mellitus (T2D). This i...

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Published in:Diabetes research and clinical practice Vol. 190; p. 109989
Main Authors: Lotan, Roni, Ravona-Springer, Ramit, Shakked, Jacob, Lin, Hung-Mo, Ouyang, Yuxia, Shahar, Danit R., Bezalel, Sharon, Agarwal, Puja, Dhana, Klodian, Heymann, Anthony, Sano, Mary, Schnaider Beeri, Michal
Format: Journal Article
Language:English
Published: Elsevier B.V 01-08-2022
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Summary:To determine associations of three dietary patterns (Mediterranean (MEDI) diet, the Dietary Approaches to Stop Hypertension (DASH) diet and the Mediterranean- DASH Intervention for Neurodegenerative Delay (MIND) diet) with cognitive decline in older adults with type 2 diabetes mellitus (T2D). This is a longitudinal observational study. Participants (N = 960) from the Israel Diabetes and Cognitive Decline (IDCD) study were included in this study. A multivariable-adjusted model including all three dietary patterns concurrently was developed to investigate their independent effect on cognitive decline. The mean follow up was 4.1 ± 2.1 years. While high adherence to both the MIND and the MEDI diet was associated with a slower decline, in the multivariable model only the associations of higher MEDI diet intake with greater decline in global cognition and in executive functions remained significant (β = 0.013, SE = 0.006; P = 0.042; β = 0.001, SE = 0.008, Pv = 0.023 respectively). In older adults with T2D, adherence to the MEDI is related to better cognitive trajectory. Diet is a meaningful factor in the path linking T2D and cognition.
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ISSN:0168-8227
1872-8227
DOI:10.1016/j.diabres.2022.109989