Search Results - "Beyer, Frauke"
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Predicting brain-age from multimodal imaging data captures cognitive impairment
Published in NeuroImage (Orlando, Fla.) (01-03-2017)“…The disparity between the chronological age of an individual and their brain-age measured based on biological information has the potential to offer clinically…”
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Impact of social isolation on grey matter structure and cognitive functions: A population-based longitudinal neuroimaging study
Published in eLife (20-06-2023)“…Social isolation has been suggested to increase the risk to develop cognitive decline. However, our knowledge on causality and neurobiological underpinnings is…”
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3
Higher BMI, but not obesity-related genetic polymorphisms, correlates with lower structural connectivity of the reward network in a population-based study
Published in International Journal of Obesity (01-03-2021)“…Background Obesity is of complex origin, involving genetic and neurobehavioral factors. Genetic polymorphisms may increase the risk for developing obesity by…”
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Towards the interpretability of deep learning models for multi-modal neuroimaging: Finding structural changes of the ageing brain
Published in NeuroImage (Orlando, Fla.) (01-11-2022)“…Brain-age (BA) estimates based on deep learning are increasingly used as neuroimaging biomarker for brain health; however, the underlying neural features have…”
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Effects of resveratrol on memory performance, hippocampus connectivity and microstructure in older adults – A randomized controlled trial
Published in NeuroImage (Orlando, Fla.) (01-07-2018)“…The polyphenol resveratrol has been suggested to exert beneficial effects on memory and the aging hippocampus due to calorie-restriction mimicking effects…”
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6
Estimating the effect of a scanner upgrade on measures of grey matter structure for longitudinal designs
Published in PloS one (05-10-2021)“…Longitudinal imaging studies are crucial for advancing the understanding of brain development over the lifespan. Thus, more and more studies acquire imaging…”
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The Obesity-Susceptibility Gene TMEM18 Promotes Adipogenesis through Activation of PPARG
Published in Cell reports (Cambridge) (20-10-2020)“…TMEM18 is the strongest candidate for childhood obesity identified from GWASs, yet as for most GWAS-derived obesity-susceptibility genes, the functional…”
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Genetic risk factors underlying white matter hyperintensities and cortical atrophy
Published in Nature communications (04-11-2024)“…White matter hyperintensities index structural abnormalities in the cerebral white matter, including axonal damage. The latter may promote atrophy of the…”
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Changes in the superior longitudinal fasciculus and anterior thalamic radiation in the left brain are associated with developmental dyscalculia
Published in Frontiers in human neuroscience (28-09-2023)“…Developmental dyscalculia is a neurodevelopmental disorder specific to arithmetic learning even with normal intelligence and age-appropriate education…”
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A Metabolic Obesity Profile Is Associated With Decreased Gray Matter Volume in Cognitively Healthy Older Adults
Published in Frontiers in aging neuroscience (02-08-2019)“…Obesity is a risk factor for cognitive decline and gray matter volume loss in aging. Studies have shown that different metabolic factors, e.g., dysregulated…”
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Neurocognitive predictors of food memory in healthy adults – A preregistered analysis
Published in Neurobiology of learning and memory (01-11-2023)“…Memory processes have long been known to determine food choices (Rozin & Zellner, 1985) but recognition memory of food and its cognitive, homeostatic and…”
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Baseline associations of cardiometabolic risk factors, executive function, and white matter microstructure in the DIRECT‐PLUS trial
Published in Alzheimer's & dementia (01-12-2021)“…Background Cardiometabolic risk factors including mid‐life obesity, diabetes and hypertension are associated with accelerated cognitive decline, e.g. in…”
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Visceral obesity relates to deep white matter hyperintensities via inflammation
Published in Annals of neurology (01-02-2019)“…Objective White matter hyperintensities (WMHs) are linked to vascular risk factors and increase the risk of cognitive decline, dementia, and stroke. We here…”
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White matter microstructural variability mediates the relation between obesity and cognition in healthy adults
Published in NeuroImage (Orlando, Fla.) (15-05-2018)“…Obesity has been linked with structural and functional brain changes. However, the impact of obesity on brain and cognition in aging remains debatable,…”
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Effects of bariatric surgery on functional connectivity of the reward and default mode network: A pre‐registered analysis
Published in Human brain mapping (01-11-2021)“…Obesity imposes serious health risks and involves alterations in resting‐state functional connectivity of brain networks involved in eating behavior. Bariatric…”
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From the reward network to whole-brain metrics: structural connectivity in adolescents and young adults according to body mass index and genetic risk of obesity
Published in International Journal of Obesity (01-04-2024)“…Background Obesity is a multifactorial condition. Genetic variants, such as the fat mass and obesity related gene (FTO) polymorphism, may increase the…”
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Cohort Profile: The LIFE-Adult-Study
Published in International journal of epidemiology (08-02-2023)Get full text
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Weight loss reduces head motion: Revisiting a major confound in neuroimaging
Published in Human brain mapping (15-06-2020)“…Head motion during magnetic resonance imaging (MRI) induces image artifacts that affect virtually every brain measure. In parallel, cross‐sectional…”
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Relationship between regional white matter hyperintensities and alpha oscillations in older adults
Published in Neurobiology of aging (01-04-2022)“…•A large sample of older adults (N = 907) with MRI and resting EEG were analyzed.•Voxel-wise white matter hyperintensities were linked to alpha…”
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Glycemic control contributes to the neuroprotective effects of Mediterranean and green-Mediterranean diets on brain age: the DIRECT PLUS brain-magnetic resonance imaging randomized controlled trial
Published in The American journal of clinical nutrition (01-11-2024)“…We recently reported that Mediterranean (MED) and green-MED diets significantly attenuated age-related brain atrophy by ∼50% within 18 mo. The objective of…”
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