Search Results - "Beyer, CF"

Gemtuzumab Ozogamicin, A Potent and Selective Anti-CD33 Antibody−Calicheamicin Conjugate for Treatment of Acute Myeloid Leukemia by Hamann, Philip R, Hinman, Lois M, Hollander, Irwin, Beyer, Carl F, Lindh, Delores, Holcomb, Ryan, Hallett, William, Tsou, Hwei-Ru, Upeslacis, Janis, Shochat, Dan, Mountain, Andrew, Flowers, David A, Bernstein, Irwin

“…CD33 is expressed by acute myeloid leukemia (AML) cells in >80% of patients but not by normal hematopoietic stem cells, suggesting that elimination of CD33+…”
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An Anti-CD33 Antibody−Calicheamicin Conjugate for Treatment of Acute Myeloid Leukemia. Choice of Linker by Hamann, Philip R, Hinman, Lois M, Beyer, Carl F, Lindh, Delores, Upeslacis, Janis, Flowers, David A, Bernstein, Irwin

“…The anti-CD33 antibody, P67.6, has been chosen to target the potently cytotoxic calicheamicin antitumor antibiotics to acute myeloid leukemia (AML) due to the…”
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Parallel synthesis and biological evaluation of 5,6,7,8-tetrahydrobenzothieno[2,3- d]pyrimidin-4(3H)-one cytotoxic agents selective for p21-deficient cells by Jennings, Lee D., Kincaid, Scott L., Wang, Yanong D., Krishnamurthy, Girija, Beyer, Carl F., McGinnis, John P., Miranda, Miriam, Discafani, Carolyn M., Rabindran, Sridhar K.

“…A novel series of anti-proliferative agents containing the thieno[2,3- d]pyrimidin-4-one scaffold and the structure–activity relationship studies to improve…”
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An Anti-MUC1 Antibody−Calicheamicin Conjugate for Treatment of Solid Tumors. Choice of Linker and Overcoming Drug Resistance by Hamann, Philip R, Hinman, Lois M, Beyer, Carl F, Greenberger, Lee M, Lin, Clara, Lindh, Delores, Menendez, Ana T, Wallace, Rosalyn, Durr, Frederick E, Upeslacis, Janis

“…The anti-MUC1 antibody, CTM01, has been chosen to target the potently cytotoxic calicheamicin antitumor antibiotics to solid tumors of epithelial origin that…”
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A Calicheamicin Conjugate with a Fully Humanized Anti-MUC1 Antibody Shows Potent Antitumor Effects in Breast and Ovarian Tumor Xenografts by Hamann, Philip R, Hinman, Lois M, Beyer, Carl F, Lindh, Delores, Upeslacis, Janis, Shochat, Dan, Mountain, Andrew

“…Murine CTM01 is an internalizing murine IgG1 monoclonal antibody that recognizes the MUC1 antigen expressed on many solid tumors of epithelial origin…”
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Photoablative inlay laser in situ keratomileusis (PAI-LASIK) in the rabbit model by Peyman, Gholam A, Beyer, Craig F, Bezerra, Yanno, Vincent, Jared M, Arosemena, Analisa, Friedlander, Miles H, Hoffmann, Laurent, Kangeler, John, Roussau, Dominique

“…To evaluate the suitability, biocompatibility, and efficacy of a proprietary hydrogel photoablative inlay (PAI) for use during laser in situ keratomileusis…”
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Mitochondrial benzodiazepine receptors mediate inhibition of mitochondrial respiratory control by Hirsch, J D, Beyer, C F, Malkowitz, L, Beer, B, Blume, A J

“…Drugs that bound to the peripheral-type or mitochondrial benzodiazepine receptors in rat kidney mitochondria produced several effects on mitochondrial…”
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Characterization of ligand binding to mitochondrial benzodiazepine receptors by Hirsch, J D, Beyer, C F, Malkowitz, L, Loullis, C C, Blume, A J

“…We have evaluated the affinity and density of binding sites for [3H]Ro5-4864 and [3H]PK11195 in intact and fragmented rat kidney mitochondria. These sites are…”
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A 'dot-immunobinding assay' on nitrocellulose membrane for the determination of the immunoglobulin class of mouse monoclonal antibodies by Beyer, C F

“…A rapid and convenient procedure for the determination of the immunoglobulin class of mouse monoclonal antibodies is described. Hybridoma supernatants or other…”
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Corneal nerve disruption reactivates virus in rabbits latently infected with HSV-1 by Beyer, CF, Hill, JM, Reidy, JJ, Beuerman, RW

“…Trauma, inflammation, and neuronal stimulation or damage can reactive latent herpes simplex virus type 1 (HSV-1). The innervation density of the corneal…”
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Herpes simplex virus and persistent epithelial defects after penetrating keratoplasty by Beyer, C F, Byrd, T J, Hill, J M, Kaufman, H E

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Herpes simplex dendritic keratitis after keratoplasty by Beyer, C F, Hill, J M, Byrd, T J, Kaufman, H E

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The coincidence of HSV-1 ocular cultures with HSV-1 corneal epithelial defects in rabbits after experimental penetrating keratoplasty by Portnoy, S L, Beyer, C F, Hill, J M, Kaufman, H E

“…Penetrating keratoplasty (PKP) in conjunction with postoperative corticosteroids may reactivate latent herpes simplex virus type 1 (HSV-1) to cause persistent…”
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Penetrating keratoplasty in rabbits induces latent HSV-1 reactivation when corticosteroids are used by Beyer, C F, Arens, M Q, Hill, J M, Rose, B T, Hill, G A, Lin, D T

“…The increased incidence of corneal graft failure in patients with herpes simplex virus (HSV) keratitis may be due in part to reactivation of latent HSV…”
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Cryogenic induced ocular HSV-1 reactivation is enhanced by an inhibitor of the lipoxygenase pathway by Beyer, C F, Tepper, D J, Hill, J M

“…Reactivation of latent herpes simplex virus type 1 (HSV-1) has been shown to occur in response to localized inflammation. Prostaglandins and lipoxygenase…”
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Periodate and Concanavalin A Induce Blast Transformation of Rat Lymphocytes by an Indirect Mechanism by Beyer, Carl F., Bowers, William E.

“…When rat lymph node cells, rendered incapable of division by treatment with mitomycin C, were then reacted with sodium metaperiodate (NaIO4), they stimulated…”
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Studies of individual amino acid residues of the decapeptide tyrocidine A by proton double-resonance difference spectroscopy in the correlation mode by Gibbons, William A, Beyer, Carl F, Dadok, Josef, Sprecher, Richard F, Wyssbrod, Herman R

“…The cyclic decapeptide antibiotic tyrocidine A was studied by two relatively new methods, viz., correlation proton magnetic resonance (pmr) spectroscopy and…”
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Cell-cell interactions in blast transformation of rat lymphocytes by neuraminidase and galactose oxidase by Kielian, M C, Beyer, C F, Bowers, W E

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A deoxyribonucleic acid-replication intermediate in the growing mosquito by Kao, P C, Beyer, C F, Lang, C A

“…In previous experiments on growth and aging in the yellow-fever mosquito, Aedes aegypti, a low mol. wt. (500000) DNA species was found in the supernatant…”
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Expulsive choroidal hemorrhage in rabbits. A histopathologic study by Beyer, C F, Peyman, G A, Hill, J M

“…Expulsive hemorrhage is a catastrophic complication of intraocular surgery that can result in total loss of vision. Suprachoroidal effusion and hemorrhage may…”
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