Search Results - "Beyer, CE"

Desvenlafaxine succinate: A new serotonin and norepinephrine reuptake inhibitor by Deecher, Darlene C, Beyer, Chad E, Johnston, Grace, Bray, Jenifer, Shah, S, Abou-Gharbia, M, Andree, Terrance H

“…The purpose of this study was to characterize a new chemical entity, desvenlafaxine succinate (DVS). DVS is a novel salt form of the isolated major active…”
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Innovative Approaches for the Development of Antidepressant Drugs: Current and Future Strategies by Schechter, Lee E., Ring, Robert H., Beyer, Chad E., Hughes, Zoë A., Khawaja, Xavier, Malberg, Jessica E., Rosenzweig-Lipson, Sharon

“…Depression is a highly debilitating disorder that has been estimated to affect up to 21% of the world population. Despite the advances in the treatment of…”
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Measurement of neurotransmitters from extracellular fluid in brain by in vivo microdialysis and chromatography–mass spectrometry by Zhang, Mei-Yi, Beyer, Chad E.

“…During the last three decades, a great deal of information has been discovered about chemical neurotransmission. However, the most important processes, namely…”
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TRPV1 Antagonists and Chronic Pain: Beyond Thermal Perception by Brandt, Michael R, Beyer, Chad E, Stahl, Stephen M

“…In the last decade, considerable evidence as accumulated to support the development of Transient Receptor Potential Vanilloid 1 (TRPV1) antagonists for the…”
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Preimplantation genetic diagnosis for chromosome rearrangements – one blastomere biopsy versus two blastomere biopsy by Brodie, D., Beyer, C. E., Osborne, E., Kralevski, V., Rasi, S., Osianlis, T.

“…Purpose Preimplantation Genetic Diagnosis (PGD) has proven to be a useful reproductive option for carriers of some chromosome rearrangements. The data…”
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Comparison of the effects of antidepressants on norepinephrine and serotonin concentrations in the rat frontal cortex: an in-vivo microdialysis study by Beyer, Chad E., Boikess, Steve, Luo, Bin, Dawson, Lee A.

“…The present study employed in-vivo microdialysis techniques in the freely moving rat to systematically compare the neurochemical effects of various…”
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Preimplantation genetic screening outcomes are associated with culture conditions by Beyer, C.E., Osianlis, T., Boekel, K., Osborne, E., Rombauts, L., Catt, J., Kralevski, V., Aali, B.S., Gras, L.

“…BACKGROUND Although preimplantation genetic screening (PGS) is widely offered, there are contradictory reports on the clinical merit of this procedure. Any…”
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The supra-additive hyperactivity caused by an amphetamine–chlordiazepoxide mixture exhibits an inverted-U dose response: Negative implications for the use of a model in screening for mood stabilizers by Kelly, Michele P., Logue, Sheree F., Dwyer, Jason M., Beyer, Chad E., Majchrowski, Heather, Cai, Zhang, Liu, Zhi, Adedoyin, Adedayo, Rosenzweig-Lipson, Sharon, Comery, Thomas A.

“…One of the few preclinical models used to identify mood stabilizers is an assay in which amphetamine-induced hyperactivity (AMPH) is potentiated by the…”
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Injections of baclofen into the ventral medial prefrontal cortex block the initiation, but not the expression, of cocaine sensitization in rats by STEKETEE, Jeffery D, BEYER, Chad E

“…Increased excitatory output from the medial prefrontal cortex (mPFC) is thought to play a key role in the development of sensitization to cocaine…”
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Antioxidant properties of melatonin—an emerging mystery by Beyer, Chad E., Steketee, Jeffery D., Saphier, David

“…Over three centuries ago, the French philosopher René Descartes described the pineal gland as “the seat of the soul.” However, it was not until the late 1950s…”
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Inhibition of uptake 2 (or extraneuronal monoamine transporter) by normetanephrine potentiates the neurochemical effects of venlafaxine by Rahman, Zia, Ring, Robert H, Young, Kimberly, Platt, Brian, Lin, Qian, Schechter, Lee E, Rosenzweig-Lipson, Sharon, Beyer, Chad E

“…Abstract Two distinct norepinephrine (NE) transporter mechanisms (uptake 1 and uptake 2) regulate extracellular NE concentrations. An association has been…”
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Neurochemical changes in the RVM associated with peripheral inflammatory pain stimuli by Smith, Valerie A., Beyer, Chad E., Brandt, Michael R.

“…A greater knowledge of the neurochemical changes occurring during pain states will undoubtedly aid in the discovery of effective pain pharmacotherapies. This…”
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Does FSH dose affect aneuploidy rates observed in human IVF embryos? by Kralevski, V, Osborne, E, Gras, L, Beyer, CE, de, Souza D, Rasi, S, Osianlis, T, Catt, J

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Anxiolytic-like activity of the non-selective galanin receptor agonist, galnon by Rajarao, S. Johannes R, Platt, Brian, Sukoff, Stacey J, Lin, Qian, Bender, Corey N, Nieuwenhuijsen, Bart W, Ring, Robert H, Schechter, Lee E, Rosenzweig-Lipson, Sharon, Beyer, Chad E

“…Abstract Galanin’s influence on monoaminergic neurotransmission, together with its discrete CNS distribution in corticolimbic brain areas, points to a…”
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WAY‐318068: a novel, potent and selective noradrenaline re‐uptake inhibitor with activity in rodent models of pain and depression by Whiteside, GT, Dwyer, JM, Harrison, JE, Beyer, CE, Cummons, T, Manzino, L, Mark, L, Johnston, GH, Strassle, BW, Adedoyin, A, Lu, P, Piesla, MJ, Pulicicchio, CM, Erve, JCL, Platt, BJ, Hughes, ZA, Rogers, KE, Deecher, DC, Trybulski, EJ, Kennedy, JD, Zhang, P, Leventhal, L

“…Background and purpose:  Antidepressants, which raise the CNS concentrations of 5‐HT and noradrenaline, are frequently used in the treatment of chronic pain;…”
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Preclinical characterization of WAY‐211612: a dual 5‐HT uptake inhibitor and 5‐HT 1A receptor antagonist and potential novel antidepressant by Beyer, CE, Lin, Q, Platt, B, Malberg, J, Hornby, G, Sullivan, KM, Smith, DL, Lock, T, Mitchell, PJ, Hatzenbuhler, NT, Evrard, DA, Harrison, BL, Magolda, R, Pangalos, MN, Schechter, LE, Rosenzweig‐Lipson, S, Andree, TH

“…Background and purpose:  As a combination of 5‐HT selective reuptake inhibitor (SSRI) with 5‐HT 1A receptor antagonism may yield a rapidly acting…”
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Dopamine depletion in the medial prefrontal cortex induces sensitized-like behavioral and neurochemical responses to cocaine by Beyer, Chad E., Steketee, Jeffery D.

“…It has been postulated that behavioral sensitization to cocaine is associated with an attenuation of cocaine-induced dopamine (DA) transmission in the medial…”
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Cocaine Sensitization: Modulation by Dopamine D sub(2) Receptors by Beyer, CE, Steketee, J D

“…Repeated administration of cocaine progressively increases drug-induced locomotor activity. This study examined the role of dopamine D sub(1)- and D…”
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PGS outcomes are associated with culture conditions by Beyer, CE, Osianlis, T, Boekel, K, Osborne, E, Rombauts, L, Catt, J, Kralevski, V, Aali, BS, Gras, L

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Preclinical characterization of WAY‐211612: a dual 5‐HT uptake inhibitor and 5‐HT1A receptor antagonist and potential novel antidepressant by Beyer, CE, Lin, Q, Platt, B, Malberg, J, Hornby, G, Sullivan, KM, Smith, DL, Lock, T, Mitchell, PJ, Hatzenbuhler, NT, Evrard, DA, Harrison, BL, Magolda, R, Pangalos, MN, Schechter, LE, Rosenzweig‐Lipson, S, Andree, TH

“…Background and purpose:  As a combination of 5‐HT selective reuptake inhibitor (SSRI) with 5‐HT1A receptor antagonism may yield a rapidly acting…”
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