Search Results - "Bever, Candace S."

Lateral flow immunoassay (LFIA) for the detection of lethal amatoxins from mushrooms by Bever, Candace S, Adams, Catharine A, Hnasko, Robert M, Cheng, Luisa W, Stanker, Larry H

“…The mushroom poison that causes the most deaths is the class of toxins known as amatoxins. Current methods to sensitively and selectively detect these toxins…”
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Rapid analysis of amatoxins in human urine by means of affinity column chromatography and liquid chromatography-high-resolution tandem mass spectrometry by Vollmer, Aline C., Fecher-Trost, Claudia, Bever, Candace S., Tam, Christina C., Wagmann, Lea, Meyer, Markus R.

“…Analysis of amatoxins is of great importance as these cyclic peptides contribute to a high number of fatalities each year. Development of analytical approaches…”
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Isolation of Alpaca Anti-Idiotypic Heavy-Chain Single-Domain Antibody for the Aflatoxin Immunoassay by Wang, Yanru, Li, Peiwu, Majkova, Zuzana, Bever, Candace R. S, Kim, Hee Joo, Zhang, Qi, Dechant, Julie E, Gee, Shirley J, Hammock, Bruce D

“…Anti-idiotypic antibodies recognize the antigenic determinants of an antibody, thus they can be used as surrogate antigens. Single-domain antibodies from…”
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Rapid, Sensitive, and Accurate Point-of-Care Detection of Lethal Amatoxins in Urine by Bever, Candace S, Swanson, Kenneth D, Hamelin, Elizabeth I, Filigenzi, Michael, Poppenga, Robert H, Kaae, Jennifer, Cheng, Luisa W, Stanker, Larry H

“…Globally, mushroom poisonings cause about 100 human deaths each year, with thousands of people requiring medical assistance. Dogs are also susceptible to…”
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Development and Utilization of Camelid VHH Antibodies from Alpaca for 2,2′,4,4′-Tetrabrominated Diphenyl Ether Detection by Bever, Candace R. S, Majkova, Zuzana, Radhakrishnan, Rajeswaran, Suni, Ian, McCoy, Mark, Wang, Yanru, Dechant, Julie, Gee, Shirley, Hammock, Bruce D

“…An antibody-based analytical method for the detection of a chemical flame retardant using antibody fragments isolated from an alpaca has been developed. One…”
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A New Conjugation Method Used for the Development of an Immunoassay for the Detection of Amanitin, a Deadly Mushroom Toxin by Bever, Candace S, Barnych, Bogdan, Hnasko, Robert, Cheng, Luisa W, Stanker, Larry H

“…One of the deadliest mushrooms is the death cap mushroom, . The most toxic constituent is α-amanitin, a bicyclic octapeptide, which damages the liver and…”
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Development and Characterization of Monoclonal Antibodies to Botulinum Neurotoxin Type E by Bever, Candace S, Scotcher, Miles, Cheng, Luisa W, Hnasko, Robert M, Stanker, Larry H

“…Botulism is a devastating disease caused by botulinum neurotoxins (BoNTs) secreted primarily by . Mouse bioassays without co-inoculation with antibodies are…”
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Heterologous Antigen Selection of Camelid Heavy Chain Single Domain Antibodies against Tetrabromobisphenol A by Wang, Jia, Bever, Candace R. S, Majkova, Zuzana, Dechant, Julie E, Yang, Jun, Gee, Shirley J, Xu, Ting, Hammock, Bruce D

“…Tetrabromobisphenol A (TBBPA) is a ubiquitous flame retardant. A high-throughput immunoassay would allow for monitoring of human and environmental exposures as…”
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One-Step Immunoassay for Tetrabromobisphenol A Using a Camelid Single Domain Antibody–Alkaline Phosphatase Fusion Protein by Wang, Jia, Majkova, Zuzana, Bever, Candace R. S, Yang, Jun, Gee, Shirley J, Li, Ji, Xu, Ting, Hammock, Bruce D

“…Tetrabromobisphenol A (TBBPA) is a ubiquitous brominated flame retardant, showing widespread environmental and human exposures. A variable domain of the heavy…”
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Nanobody Based Immunoassay for Human Soluble Epoxide Hydrolase Detection Using Polymeric Horseradish Peroxidase (PolyHRP) for Signal Enhancement: The Rediscovery of PolyHRP? by Li, Dongyang, Cui, Yongliang, Morisseau, Christophe, Gee, Shirley J, Bever, Candace S, Liu, Xiangjiang, Wu, Jian, Hammock, Bruce D, Ying, Yibin

“…Soluble epoxide hydrolase (sEH) is a potential pharmacological target for treating hypertension, vascular inflammation, cancer, pain, and multiple…”
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Effects of triclosan in breast milk on the infant fecal microbiome by Bever, Candace S., Rand, Amy A., Nording, Malin, Taft, Diana, Kalanetra, Karen M., Mills, David A., Breck, Melissa A., Smilowitz, Jennifer T., German, J. Bruce, Hammock, Bruce D.

“…Triclosan is frequently used for its antimicrobial properties and has been detected in human serum, urine, and breast milk. Animal and molecular studies have…”
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Comparison of soybean peroxidase with horseradish peroxidase and alkaline phosphatase used in immunoassays by Yang, Huijuan, Bever, Candace S., Zhang, Huiyan, Mari, Ghulam Mujtaba, Li, Hongfang, Zhang, Xiya, Guo, Liuchuan, Wang, Ziwen, Luo, Pengjie, Wang, Zhanhui

“…Enzyme labeling of an antigen or an antibody helps to visualize and amplify the signal and is an important reagent used in immunoassays for the detection of a…”
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Smartphone-based paper microfluidic competitive immunoassay for the detection of α-amanitin from mushrooms by Liang, Yan, Zhou, Avory, Bever, Candace S., Cheng, Luisa W., Yoon, Jeong-Yeol

“…α-Amanitin is often considered the most poisonous mushroom toxin produced by various mushroom species, which are hard to identify from edible, non-toxic…”
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Impedance Biosensors: Applications to Sustainability and Remaining Technical Challenges by Radhakrishnan, Rajeswaran, Suni, Ian I, Bever, Candace S, Hammock, Bruce D

“…Due to their all-electrical nature, impedance biosensors have significant potential for use as simple and portable sensors for environmental studies and…”
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Competitive and noncompetitive immunoassays for the detection of benzothiostrobin using magnetic nanoparticles and fluorescein isothiocyanate-labeled peptides by Chen, He, Yang, Qian, Ding, Yuan, Vasylieva, Natalia, Bever, Candace S., Hua, Xiude, Wang, Minghua, Hammock, Bruce D.

“…Phage-displayed peptides have been proven to be powerful reagents for competitive and noncompetitive immunoassays. However, they are unconventional reagents,…”
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Smartphone-interfaced lab-on-a-chip devices for field-deployable enzyme-linked immunosorbent assay by Chen, Arnold, Wang, Royal, Bever, Candace R S, Xing, Siyuan, Hammock, Bruce D, Pan, Tingrui

“…The emerging technologies on mobile-based diagnosis and bioanalytical detection have enabled powerful laboratory assays such as enzyme-linked immunosorbent…”
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Detection of the Antimicrobial Triclosan in Environmental Samples by Immunoassay by Ahn, Ki Chang, Ranganathan, Anupama, Bever, Candace S, Hwang, Sung Hee, Holland, Erika B, Morisseau, Kevin, Pessah, Isaac N, Hammock, Bruce D, Gee, Shirley J

“…A sensitive, competitive enzyme-linked immunosorbent assay (ELISA) for the detection of the antimicrobial triclosan (TCS; 2,4,4′-trichloro-2′-hydroxydiphenyl…”
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A Rapid Extraction Method Combined with a Monoclonal Antibody-Based Immunoassay for the Detection of Amatoxins by Bever, Candace S, Hnasko, Robert M, Cheng, Luisa W, Stanker, Larry H

“…Amatoxins (AMAs) are lethal toxins found in a variety of mushroom species. Detection methods are needed to determine the occurrence of AMAs in mushroom species…”
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VHH antibodies: emerging reagents for the analysis of environmental chemicals by Bever, Candace S., Dong, Jie-Xian, Vasylieva, Natalia, Barnych, Bogdan, Cui, Yongliang, Xu, Zhen-Lin, Hammock, Bruce D., Gee, Shirley J.

“…A VHH antibody (or nanobody) is the antigen binding fragment of heavy chain only antibodies. Discovered nearly 25 years ago, they have been investigated for…”
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Method for Sorting and Pairwise Selection of Nanobodies for the Development of Highly Sensitive Sandwich Immunoassays by Rossotti, Martín A, Pirez, Macarena, Gonzalez-Techera, Andres, Cui, Yongliang, Bever, Candace S, Lee, Kin S. S, Morisseau, Christophe, Leizagoyen, Carmen, Gee, Shirley, Hammock, Bruce D, González-Sapienza, Gualberto

“…Single domain heavychain binders (nanobodies) obtained from camelid antibody libraries hold a great promise for immunoassay development. However, there is no…”
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