Search Results - "Bevan, D."

Dopaminergic Transmission Rapidly and Persistently Enhances Excitability of D1 Receptor-Expressing Striatal Projection Neurons by Lahiri, Asha K., Bevan, Mark D.

“…Substantia nigra dopamine neurons have been implicated in the initiation and invigoration of movement, presumably through their modulation of striatal…”
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Mush Amalgamation, Short Residence, and Sparse Detectability of Eruptible Magma Before Andean Super‐Eruptions by Weber, G., Blundy, J., Bevan, D.

“…Giant volcanic eruptions have the potential to overturn civilizations. Yet, the driving mechanism and timescale over which batholithic magma reservoirs…”
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Heterosynaptic regulation of external globus pallidus inputs to the subthalamic nucleus by the motor cortex by Chu, Hong-Yuan, Atherton, Jeremy F, Wokosin, David, Surmeier, D James, Bevan, Mark D

“…The two principal movement-suppressing pathways of the basal ganglia, the so-called hyperdirect and indirect pathways, interact within the subthalamic nucleus…”
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Loss of Hyperdirect Pathway Cortico-Subthalamic Inputs Following Degeneration of Midbrain Dopamine Neurons by Chu, Hong-Yuan, McIver, Eileen L., Kovaleski, Ryan F., Atherton, Jeremy F., Bevan, Mark D.

“…The motor symptoms of Parkinson’s disease (PD) are linked to abnormally correlated and coherent activity in the cortex and subthalamic nucleus (STN). However,…”
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New roles for the external globus pallidus in basal ganglia circuits and behavior by Gittis, Aryn H, Berke, Joshua D, Bevan, Mark D, Chan, C Savio, Mallet, Nicolas, Morrow, Michelle M, Schmidt, Robert

“…The development of methodology to identify specific cell populations and circuits within the basal ganglia is rapidly transforming our ability to understand…”
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Sonoporation by Ultrasound-Activated Microbubble Contrast Agents: Effect of Acoustic Exposure Parameters on Cell Membrane Permeability and Cell Viability by Karshafian, Raffi, Bevan, Peter D, Williams, Ross, Samac, Sanya, Burns, Peter N

“…Abtract This work investigates the effect of ultrasound exposure parameters on the sonoporation of KHT-C cells in suspension by perflutren microbubbles…”
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Movement-related increases in subthalamic activity optimize locomotion by Callahan, Joshua W., Morales, Juan Carlos, Atherton, Jeremy F., Wang, Dorothy, Kostic, Selena, Bevan, Mark D.

“…The subthalamic nucleus (STN) is traditionally thought to restrict movement. Lesion or prolonged STN inhibition increases movement vigor and propensity, while…”
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Proliferation of external globus pallidus-subthalamic nucleus synapses following degeneration of midbrain dopamine neurons by Fan, Kai Y, Baufreton, Jérôme, Surmeier, D James, Chan, C Savio, Bevan, Mark D

“…The symptoms of Parkinson's disease (PD) are related to changes in the frequency and pattern of activity in the reciprocally connected GABAergic external…”
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Intrinsic dynamics and synaptic inputs control the activity patterns of subthalamic nucleus neurons in health and in Parkinson's disease by Wilson, C.J, Bevan, M.D

“…Abstract Neurons in the subthalamic nucleus occupy a pivotal position in the circuitry of the basal ganglia. They receive direct excitatory input from the…”
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Pharmacokinetic and pharmacodynamic properties of plasma‐derived vs. recombinant factor IX in patients with hemophilia B: a prospective crossover study by Alamelu, J., Bevan, D., Sorensen, B., Rangarajan, S.

“…Summary Background Effective treatment of acute bleeding episodes in patients with hemophilia B relies on factor IX recovery, with higher levels being more…”
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Short-term depression of external globus pallidus-subthalamic nucleus synaptic transmission and implications for patterning subthalamic activity by Atherton, Jeremy F, Menard, Ariane, Urbain, Nadia, Bevan, Mark D

“…The frequency and pattern of activity in the reciprocally connected GABAergic external globus pallidus (GPe) and glutamatergic subthalamic nucleus (STN) are…”
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Microbubble mediated sonoporation of cells in suspension: Clonogenic viability and influence of molecular size on uptake by Karshafian, Raffi, Samac, Sanya, Bevan, Peter D., Burns, Peter N.

“…This work investigates whether the application of sonoporation is limited by the size of a macromolecule being delivered and by the ability of cells to…”
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A High-Throughput Screening Method for the Determination of Aqueous Drug Solubility Using Laser Nephelometry in Microtiter Plates by Bevan, Christopher D, Lloyd, Richard S

“…The determination of aqueous solubility in a high-throughput screening environment is invaluable in the selection of the most promising potential drug…”
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Mechanisms Underlying Spontaneous Oscillation and Rhythmic Firing in Rat Subthalamic Neurons by Bevan, Mark D, Wilson, Charles J

“…Subthalamic neurons drive basal ganglia output neurons in resting animals and relay cortical and thalamic activity to the same output neurons during movement…”
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A population study to define the incidence and survival of multiple myeloma in a National Health Service Region in UK by Phekoo, K. J., Schey, S. A., Richards, M. A., Bevan, D. H., Bell, S., Gillett, D., Møller, H.

“…Summary Epidemiology data on multiple myeloma (MM) occurrence and outcome is inconsistent whilst a major limitation of randomized controlled trials is…”
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Enhancement of Excitatory Synaptic Integration by GABAergic Inhibition in the Subthalamic Nucleus by Baufreton, Jerome, Atherton, Jeremy F, Surmeier, D. James, Bevan, Mark D

“…The activity patterns of subthalamic nucleus (STN) neurons, which are intimately related to normal movement and abnormal movement in Parkinson's disease (PD),…”
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D2-like dopamine receptor-mediated modulation of activity-dependent plasticity at GABAergic synapses in the subthalamic nucleus by Baufreton, Jérôme, Bevan, Mark D.

“…Reciprocally connected glutamatergic subthalamic nucleus (STN) and GABAergic external globus pallidus (GP) neurons normally exhibit weakly correlated,…”
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Microcircuitry of the direct and indirect pathways of the basal ganglia by SMITH, Y, BEVAN, M. D, SHINK, E, BOLAM, J. P

“…Our understanding of the organization of the basal ganglia has advanced markedly over the last 10 years, mainly due to increased knowledge of their anatomical,…”
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Sparse but Selective and Potent Synaptic Transmission From the Globus Pallidus to the Subthalamic Nucleus by Baufreton, Jerome, Kirkham, Erin, Atherton, Jeremy F, Menard, Ariane, Magill, Peter J, Bolam, J. Paul, Bevan, Mark D

“…1 Department of Physiology, Northwestern University, Chicago Illinois; 2 Université de Bordeaux 2; Centre National de la Recherche Scientifique, Unité Mixte de…”
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Relationship of Activity in the Subthalamic Nucleus-Globus Pallidus Network to Cortical Electroencephalogram by Magill, Peter J, Bolam, J. Paul, Bevan, Mark D

“…One of the functions of the excitatory subthalamic nucleus (STN) is to relay cortical activity to other basal ganglia structures. The response of the STN to…”
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