Search Results - "Beutler, S"

Clinical Course of Oxaliplatin-Induced Neuropathy: Results From the Randomized Phase III Trial N08CB (Alliance) by Pachman, Deirdre R, Qin, Rui, Seisler, Drew K, Smith, Ellen M L, Beutler, Andreas S, Ta, Lauren E, Lafky, Jacqueline M, Wagner-Johnston, Nina D, Ruddy, Kathryn J, Dakhil, Shaker, Staff, Nathan P, Grothey, Axel, Loprinzi, Charles L

“…Given that the clinical course of oxaliplatin-induced neuropathy is not well defined, the current study was performed to better understand clinical parameters…”
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SERE: single-parameter quality control and sample comparison for RNA-Seq by Schulze, Stefan K, Kanwar, Rahul, Gölzenleuchter, Meike, Therneau, Terry M, Beutler, Andreas S

“…Assessing the reliability of experimental replicates (or global alterations corresponding to different experimental conditions) is a critical step in analyzing…”
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The genomic landscape of small intestine neuroendocrine tumors by Banck, Michaela S, Kanwar, Rahul, Kulkarni, Amit A, Boora, Ganesh K, Metge, Franziska, Kipp, Benjamin R, Zhang, Lizhi, Thorland, Erik C, Minn, Kay T, Tentu, Ramesh, Eckloff, Bruce W, Wieben, Eric D, Wu, Yanhong, Cunningham, Julie M, Nagorney, David M, Gilbert, Judith A, Ames, Matthew M, Beutler, Andreas S

“…Small intestine neuroendocrine tumors (SI-NETs) are the most common malignancy of the small bowel. Several clinical trials target PI3K/Akt/mTOR signaling;…”
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Oxaliplatin-Induced Peripheral Neuropathy and Identification of Unique Severity Groups in Colorectal Cancer by Griffith, Kathleen A., Zhu, Shijun, Johantgen, Meg, Kessler, Michael D., Renn, Cynthia, Beutler, Andreas S., Kanwar, Rahul, Ambulos, Nicholas, Cavaletti, Guido, Bruna, Jordi, Briani, Chiara, Argyriou, Andreas A., Kalofonos, Haralabos P., Yerges-Armstrong, Laura M., Dorsey, Susan G.

“…Oxaliplatin-induced peripheral neuropathy (OIPN) is a dose-limiting toxicity of oxaliplatin and affects most colorectal cancer patients. OIPN is commonly…”
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Randomised controlled trial on the effect of clomiphene citrate and gonadotropin dose on ovarian response markers and IVF outcomes in poor responders by Moffat, R, Hansali, C, Schoetzau, A, Ahler, A, Gobrecht, U, Beutler, S, Raggi, A, Sartorius, G, De Geyter, C

“…Abstract STUDY QUESTION Does the gonadotropin (GN) starting dose and the addition of clomiphene citrate (CC) during the early follicular phase influence oocyte…”
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Patient-reported (EORTC QLQ-CIPN20) versus physician-reported (CTCAE) quantification of oxaliplatin- and paclitaxel/carboplatin-induced peripheral neuropathy in NCCTG/Alliance clinical trials by Le-Rademacher, Jennifer, Kanwar, Rahul, Seisler, Drew, Pachman, Deirdre R., Qin, Rui, Abyzov, Alexej, Ruddy, Kathryn J., Banck, Michaela S., Lavoie Smith, Ellen M., Dorsey, Susan G., Aaronson, Neil K., Sloan, Jeff, Loprinzi, Charles L., Beutler, Andreas S.

“…Purpose Clinical practice guidelines on chemotherapy-induced peripheral neuropathy (CIPN) use the NCI Common Terminology Criteria for Adverse Events (CTCAE),…”
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Postoperative Pain Management in Enhanced Recovery Pathways by Cheung, Christopher K, Adeola, Janet O, Beutler, Sascha S, Urman, Richard D

“…Postoperative pain is a common but often inadequately treated condition. Enhanced recovery pathways (ERPs) are increasingly being utilized to standardize…”
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Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505) by Pachman, Deirdre R., Qin, Rui, Seisler, Drew, Smith, Ellen M. Lavoie, Kaggal, Suneetha, Novotny, Paul, Ruddy, Kathryn J., Lafky, Jacqueline M., Ta, Lauren E., Beutler, Andreas S., Wagner-Johnston, Nina D., Staff, Nathan P., Grothey, Axel, Dougherty, Patrick M., Cavaletti, Guido, Loprinzi, Charles L.

“…Purpose Oxaliplatin and paclitaxel are commonly used chemotherapies associated with acute and chronic neuropathies. There is a need to better understand the…”
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A pilot study of minocycline for the prevention of paclitaxel-associated neuropathy: ACCRU study RU221408I by Pachman, Deirdre R., Dockter, Travis, Zekan, Patricia J., Fruth, Briant, Ruddy, Kathryn J., Ta, Lauren E., Lafky, Jacqueline M., Dentchev, Todor, Le-Lindqwister, Nguyet Anh, Sikov, William M., Staff, Nathan, Beutler, Andreas S., Loprinzi, Charles L.

“…Purpose Paclitaxel is associated with both an acute pain syndrome (P-APS) and chronic chemotherapy-induced peripheral neuropathy (CIPN). Given that extensive…”
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Clinical magnetic resonance-enabled characterization of mono-iodoacetate-induced osteoarthritis in a large animal species by Unger, Mark D, Murthy, Naveen S, Kanwar, Rahul, Strand, Kasey A, Maus, Timothy P, Beutler, Andreas S

“…Osteoarthritis (OA) is the most common form of arthritis. Medical and surgical treatments have yet to substantially diminish the global health and economic…”
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Quantitation of Gait and Stance Alterations Due to Monosodium Iodoacetate-induced Knee Osteoarthritis in Yucatan Swine by LaVallee, Katherine T, Maus, Timothy P, Stock, Joseph D, Stalder, Kenneth J, Karriker, Locke A, Murthy, Naveen S, Kanwar, Rahul, Beutler, Andrea S, Unger, Mark D

“…Knee osteoarthritis is one of the most common causes of chronic pain worldwide, and several animal models have been developed to investigate disease mechanisms…”
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Patient factors associated with discrepancies between patient-reported and clinician-documented peripheral neuropathy in women with breast cancer receiving paclitaxel: A pilot study by Salgado, Teresa M., Liu, Jin, Reed, Holly L., Quinn, Caroline S., Syverson, Jillian G., Le-Rademacher, Jennifer, Lopez, Camden L., Beutler, Andreas S., Loprinzi, Charles L., Vangipuram, Kiran, Smith, Ellen M. Lavoie, Henry, N Lynn, Farris, Karen B., Hertz, Daniel L.

“…Discrepancies between clinicians’ assessment of chemotherapy-induced peripheral neuropathy (CIPN) and patient-reported outcomes (PRO) have been described,…”
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Sensory neuron targeting by self-complementary AAV8 via lumbar puncture for chronic pain by Storek, Benjamin, Reinhardt, Matthias, Wang, Cheng, Janssen, William G.M, Harder, Nina M, Banck, Michaela S, Morrison, John H, Beutler, Andreas S

“…Lumbar puncture (LP) is an attractive route to deliver drugs to the nervous system because it is a safe bedside procedure. Its use for gene therapy has been…”
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Recombinant LH supplementation to a standard GnRH antagonist protocol in women of 35 years or older undergoing IVF/ICSI: a randomized controlled multicentre study by König, T.E., van der Houwen, L.E.E., Overbeek, A., Hendriks, M.L., Beutler-Beemsterboer, S.N., Kuchenbecker, W.K.H., Renckens, C.N.M., Bernardus, R.E., Schats, R., Homburg, R., Hompes, P.G.A., Lambalk, C.B.

“…STUDY QUESTION Does the addition of exogenous LH to an IVF/ICSI stimulation protocol with recombinant FSH (r-FSH) and a GnRH antagonist improve the ovarian…”
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Carbamazepine is an inhibitor of histone deacetylases by Beutler, Andreas S., Li, SiDe, Nicol, Rebekka, Walsh, Martin J.

“…Carbamazepine (CBZ) is a common antiepileptic drug (AED) that acts through multiple mechanisms including blockade and potentiation of cation channels and…”
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Genetic Variations and Health-Related Quality of Life (HRQOL): A Genome-Wide Study Approach by Adjei, Araba A, Lopez, Camden L, Schaid, Daniel J, Sloan, Jeff A, Le-Rademacher, Jennifer G, Loprinzi, Charles L, Norman, Aaron D, Olson, Janet E, Couch, Fergus J, Beutler, Andreas S, Vachon, Celine M, Ruddy, Kathryn J

“…Health-related quality of life (HRQOL) is an important prognostic patient-reported outcome in oncology. Because prior studies suggest that HRQOL is, in part,…”
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Pharmacologic Properties of Novel Local Anesthetic Agents in Anesthesia Practice by King, Chih H., MD, PhD, Beutler, Sascha S., MD, PhD, Kaye, Alan D., PhD, DABA, DABPM, DABIPP, Urman, Richard D., MD, MBA

“…Therapeutic duration of traditional local anesthetics when used in peripheral nerve blocks is normally limited. This article describes novel approaches to…”
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The ZNF217 oncogene is a candidate organizer of repressive histone modifiers by Banck, Michaela S, Li, Side, Nishio, Hitomi, Wang, Cheng, Beutler, Andreas S, Walsh, Martin J

“…The zinc finger protein 217 (ZNF217) is an important oncogene based on the high frequency of amplification and over-expression in many cancer types, but its…”
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Potential Opioid-Related Adverse Drug Events Are Associated With Decreased Revenue in Hip Replacement Surgery in the Older Population by Baker, Justin, Brovman, Ethan Y., Rao, Nikhilesh, Beutler, Sascha S., Urman, Richard D.

“…Introduction: Opioid-related adverse drug events (ORADEs) are an increasingly recognized complication associated with the common prescription of opioids after…”
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Preclinical Toxicity Evaluation of AAV for Pain: Evidence from Human AAV Studies and from the Pharmacology of Analgesic Drugs by Pleticha, Josef, Heilmann, Lukas F, Evans, Christopher H, Asokan, Aravind, Samulski, Richard Jude, Beutler, Andreas S

“…Gene therapy with adeno-associated virus (AAV) has advanced in the last few years from promising results in animal models to >100 clinical trials (reported or…”
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