Search Results - "Beutler, Andreas"

Clinical Course of Oxaliplatin-Induced Neuropathy: Results From the Randomized Phase III Trial N08CB (Alliance) by Pachman, Deirdre R, Qin, Rui, Seisler, Drew K, Smith, Ellen M L, Beutler, Andreas S, Ta, Lauren E, Lafky, Jacqueline M, Wagner-Johnston, Nina D, Ruddy, Kathryn J, Dakhil, Shaker, Staff, Nathan P, Grothey, Axel, Loprinzi, Charles L

“…Given that the clinical course of oxaliplatin-induced neuropathy is not well defined, the current study was performed to better understand clinical parameters…”
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SERE: single-parameter quality control and sample comparison for RNA-Seq by Schulze, Stefan K, Kanwar, Rahul, Gölzenleuchter, Meike, Therneau, Terry M, Beutler, Andreas S

“…Assessing the reliability of experimental replicates (or global alterations corresponding to different experimental conditions) is a critical step in analyzing…”
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The genomic landscape of small intestine neuroendocrine tumors by Banck, Michaela S, Kanwar, Rahul, Kulkarni, Amit A, Boora, Ganesh K, Metge, Franziska, Kipp, Benjamin R, Zhang, Lizhi, Thorland, Erik C, Minn, Kay T, Tentu, Ramesh, Eckloff, Bruce W, Wieben, Eric D, Wu, Yanhong, Cunningham, Julie M, Nagorney, David M, Gilbert, Judith A, Ames, Matthew M, Beutler, Andreas S

“…Small intestine neuroendocrine tumors (SI-NETs) are the most common malignancy of the small bowel. Several clinical trials target PI3K/Akt/mTOR signaling;…”
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Oxaliplatin-Induced Peripheral Neuropathy and Identification of Unique Severity Groups in Colorectal Cancer by Griffith, Kathleen A., Zhu, Shijun, Johantgen, Meg, Kessler, Michael D., Renn, Cynthia, Beutler, Andreas S., Kanwar, Rahul, Ambulos, Nicholas, Cavaletti, Guido, Bruna, Jordi, Briani, Chiara, Argyriou, Andreas A., Kalofonos, Haralabos P., Yerges-Armstrong, Laura M., Dorsey, Susan G.

“…Oxaliplatin-induced peripheral neuropathy (OIPN) is a dose-limiting toxicity of oxaliplatin and affects most colorectal cancer patients. OIPN is commonly…”
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National Cancer Institute-supported chemotherapy-induced peripheral neuropathy trials: outcomes and lessons by Majithia, Neil, Temkin, Sarah M., Ruddy, Kathryn J., Beutler, Andreas S., Hershman, Dawn L., Loprinzi, Charles L.

“…Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most common and debilitating complications of cancer treatment. Due to a lack of effective…”
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Patient-reported (EORTC QLQ-CIPN20) versus physician-reported (CTCAE) quantification of oxaliplatin- and paclitaxel/carboplatin-induced peripheral neuropathy in NCCTG/Alliance clinical trials by Le-Rademacher, Jennifer, Kanwar, Rahul, Seisler, Drew, Pachman, Deirdre R., Qin, Rui, Abyzov, Alexej, Ruddy, Kathryn J., Banck, Michaela S., Lavoie Smith, Ellen M., Dorsey, Susan G., Aaronson, Neil K., Sloan, Jeff, Loprinzi, Charles L., Beutler, Andreas S.

“…Purpose Clinical practice guidelines on chemotherapy-induced peripheral neuropathy (CIPN) use the NCI Common Terminology Criteria for Adverse Events (CTCAE),…”
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Biological predictors of chemotherapy-induced peripheral neuropathy (CIPN): MASCC neurological complications working group overview by Chan, Alexandre, Hertz, Daniel L., Morales, Manuel, Adams, Elizabeth J., Gordon, Sharon, Tan, Chia Jie, Staff, Nathan P., Kamath, Jayesh, Oh, Jeong, Shinde, Shivani, Pon, Doreen, Dixit, Niharkia, D’Olimpio, James, Dumitrescu, Cristina, Gobbo, Margherita, Kober, Kord, Mayo, Samantha, Pang, Linda, Subbiah, Ishwaria, Beutler, Andreas S., Peters, Katherine B., Loprinzi, Charles, Lustberg, Maryam B.

“…Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating condition associated with a number of chemotherapeutic agents. Drugs commonly…”
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Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505) by Pachman, Deirdre R., Qin, Rui, Seisler, Drew, Smith, Ellen M. Lavoie, Kaggal, Suneetha, Novotny, Paul, Ruddy, Kathryn J., Lafky, Jacqueline M., Ta, Lauren E., Beutler, Andreas S., Wagner-Johnston, Nina D., Staff, Nathan P., Grothey, Axel, Dougherty, Patrick M., Cavaletti, Guido, Loprinzi, Charles L.

“…Purpose Oxaliplatin and paclitaxel are commonly used chemotherapies associated with acute and chronic neuropathies. There is a need to better understand the…”
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A pilot study of minocycline for the prevention of paclitaxel-associated neuropathy: ACCRU study RU221408I by Pachman, Deirdre R., Dockter, Travis, Zekan, Patricia J., Fruth, Briant, Ruddy, Kathryn J., Ta, Lauren E., Lafky, Jacqueline M., Dentchev, Todor, Le-Lindqwister, Nguyet Anh, Sikov, William M., Staff, Nathan, Beutler, Andreas S., Loprinzi, Charles L.

“…Purpose Paclitaxel is associated with both an acute pain syndrome (P-APS) and chronic chemotherapy-induced peripheral neuropathy (CIPN). Given that extensive…”
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Future Directions in Pain Management: Integrating Anatomically Selective Delivery Techniques With Novel Molecularly Selective Agents by Pleticha, Josef, Maus, Timothy P, Beutler, Andreas S

“…Treatment for chronic, locoregional pain ranks among the most prevalent unmet medical needs. The failure of systemic analgesic drugs, such as opioids, is often…”
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Response to “Unilateral Periganglionic Resiniferatoxin (RTX) for Personalized Pain Treatment” by Beutler, Andreas S, Unger, Mark D, Banck, Michaela S, Maus, Timothy P

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Clinical magnetic resonance-enabled characterization of mono-iodoacetate-induced osteoarthritis in a large animal species by Unger, Mark D, Murthy, Naveen S, Kanwar, Rahul, Strand, Kasey A, Maus, Timothy P, Beutler, Andreas S

“…Osteoarthritis (OA) is the most common form of arthritis. Medical and surgical treatments have yet to substantially diminish the global health and economic…”
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Randomized controlled trial of cryotherapy to prevent paclitaxel-induced peripheral neuropathy (RU221511I); an ACCRU trial by Ruddy, Kathryn J., Le-Rademacher, Jennifer, Lacouture, Mario E., Wilkinson, Mary, Onitilo, Adedayo A., Vander Woude, Amy C., Grosse-Perdekamp, Maria T., Dockter, Travis, Tan, Angelina D., Beutler, Andreas, Loprinzi, Charles L.

“…This pilot trial aimed to assess if cooling hands and feet with crushed ice during receipt of paclitaxel helps prevent peripheral neuropathy. This prospective,…”
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Sequencing of Charcot-Marie-Tooth disease genes in a toxic polyneuropathy by Beutler, Andreas S., Kulkarni, Amit A., Kanwar, Rahul, Klein, Christopher J., Therneau, Terry M., Qin, Rui, Banck, Michaela S., Boora, Ganesh K., Ruddy, Kathryn J., Wu, Yanhong, Smalley, Regenia L., Cunningham, Julie M., Le-Lindqwister, Nguyet Anh, Beyerlein, Peter, Schroth, Gary P., Windebank, Anthony J., Züchner, Stephan, Loprinzi, Charles L.

“…Objective Mutations in Charcot–Marie–Tooth disease (CMT) genes are the cause of rare familial forms of polyneuropathy. Whether allelic variability in CMT genes…”
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MRI guidance technology development in a large animal model for hyperlocal analgesics delivery to the epidural space and dorsal root ganglion by Maus, Timothy P., Felmlee, Joel P., Unger, Mark D., Beutler, Andreas S.

“…Development of new analgesic drugs or gene therapy vectors for spinal delivery will be facilitated by “hyperlocal” targeting of small therapeutic injectate…”
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Genetic variation in EPHA contributes to sensitivity to paclitaxel‐induced peripheral neuropathy by Marcath, Lauren A., Kidwell, Kelley M., Vangipuram, Kiran, Gersch, Christina L., Rae, James M., Burness, Monika L., Griggs, Jennifer J., Van Poznak, Catherine, Hayes, Daniel F., Smith, Ellen M. Lavoie, Henry, N. Lynn, Beutler, Andreas S., Hertz, Daniel L.

“…Aims Chemotherapy‐induced peripheral neuropathy (PN) is a treatment limiting toxicity of paclitaxel. We evaluated if EPHA genetic variation (EPHA4, EPHA5,…”
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Association of the Charcot–Marie–Tooth disease gene ARHGEF10 with paclitaxel induced peripheral neuropathy in NCCTG N08CA (Alliance) by Boora, Ganesh K, Kulkarni, Amit A, Kanwar, Rahul, Beyerlein, Peter, Qin, Rui, Banck, Michaela S, Ruddy, Kathryn J, Pleticha, Josef, Lynch, Cynthia A, Behrens, Robert J, Züchner, Stephan, Loprinzi, Charles L, Beutler, Andreas S

“…Abstract The predisposition of patients to develop polyneuropathy in response to toxic exposure may have a genetic basis. The previous study Alliance N08C1…”
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Genetic variation in Charcot–Marie–Tooth genes contributes to sensitivity to paclitaxel-induced peripheral neuropathy by Chen, Yongzhen, Fang, Fang, Kidwell, Kelley M, Vangipuram, Kiran, Marcath, Lauren A, Gersch, Christina L, Rae, James M, Hayes, Daniel F, Lavoie Smith, Ellen M, Henry, N Lynn, Beutler, Andreas S, Hertz, Daniel L

“…This study explored whether inherited variants in genes causing the hereditary neuropathy condition Charcot–Marie–Tooth disease are associated with sensitivity…”
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Scrambler Therapy for the management of chronic pain by Majithia, Neil, Smith, Thomas J., Coyne, Patrick J., Abdi, Salahadin, Pachman, Deirdre R., Lachance, Daniel, Shelerud, Randy, Cheville, Andrea, Basford, Jeffrey R., Farley, David, O’Neill, Carrie, Ruddy, Kathryn J., Sparadeo, Frank, Beutler, Andreas, Loprinzi, Charles L

“…Purpose Chronic pain is a widespread and debilitating condition, encountered by physicians in a variety of practice settings. Although many pharmacologic and…”
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Exome-level comparison of primary well-differentiated neuroendocrine tumors and their cell lines by Boora, Ganesh K, Kanwar, Rahul, Kulkarni, Amit A, Pleticha, Josef, Ames, Matthew, Schroth, Gary, Beutler, Andreas S, Banck, Michaela S

“…Neuroendocrine cancer cell lines are used to investigate therapeutic targets in neuroendocrine tumors (NET) and have been instrumental in the design of…”
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