Search Results - "Beuschlein, Felix"

Adrenocortical carcinoma — towards genomics guided clinical care by Crona, Joakim, Beuschlein, Felix

“…Adrenocortical carcinoma (ACC) is an aggressive and rare neoplasm that originates in the cortex of the adrenal gland. The disease is associated with…”
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Personalized Management of Pheochromocytoma and Paraganglioma by Nölting, Svenja, Bechmann, Nicole, Taieb, David, Beuschlein, Felix, Fassnacht, Martin, Kroiss, Matthias, Eisenhofer, Graeme, Grossman, Ashley, Pacak, Karel

“…Pheochromocytomas/paragangliomas are characterized by a unique molecular landscape that allows their assignment to clusters based on underlying genetic…”
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Subclinical hypercortisolism: a state, a syndrome, or a disease? by Di Dalmazi, Guido, Pasquali, Renato, Beuschlein, Felix, Reincke, Martin

“…Subclinical hypercortisolism (SH), defined as alterations of the hypothalamus–pituitary–adrenal axis in the absence of clinical signs or symptoms related to…”
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Genetics, prevalence, screening and confirmation of primary aldosteronism: a position statement and consensus of the Working Group on Endocrine Hypertension of The European Society of Hypertension by Mulatero, Paolo, Monticone, Silvia, Deinum, Jaap, Amar, Laurence, Prejbisz, Aleksander, Zennaro, Maria-Christina, Beuschlein, Felix, Rossi, Gian Paolo, Nishikawa, Tetsuo, Morganti, Alberto, Seccia, Teresa Maria, Lin, Yen-Hung, Fallo, Francesco, Widimsky, Jiri

“…Autonomous aldosterone overproduction represents the underlying condition of 5–10% of patients with arterial hypertension and carries a significant burden of…”
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International Histopathology Consensus for Unilateral Primary Aldosteronism by Williams, Tracy Ann, Gomez-Sanchez, Celso E, Rainey, William E, Giordano, Thomas J, Lam, Alfred K, Marker, Alison, Mete, Ozgur, Yamazaki, Yuto, Zerbini, Maria Claudia Nogueira, Beuschlein, Felix, Satoh, Fumitoshi, Burrello, Jacopo, Schneider, Holger, Lenders, Jacques W M, Mulatero, Paolo, Castellano, Isabella, Knösel, Thomas, Papotti, Mauro, Saeger, Wolfgang, Sasano, Hironobu, Reincke, Martin

“…Abstract Objective Develop a consensus for the nomenclature and definition of adrenal histopathologic features in unilateral primary aldosteronism (PA)…”
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Secondary hypertension as a cause of treatment resistance by Sudano, Isabella, Suter, Paolo, Beuschlein, Felix

“…In secondary hypertension, elevated blood pressure is caused by a known and/or potentially treatable underlying disease. Although the prevalence of secondary…”
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β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis by Leng, Sining, Pignatti, Emanuele, Khetani, Radhika S., Shah, Manasvi S., Xu, Simiao, Miao, Ji, Taketo, Makoto M., Beuschlein, Felix, Barrett, Paula Q., Carlone, Diana L., Breault, David T.

“…Rosettes are widely used in epithelial morphogenesis during embryonic development and organogenesis. However, their role in postnatal development and adult…”
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Biochemical Diagnosis of Chromaffin Cell Tumors in Patients at High and Low Risk of Disease: Plasma versus Urinary Free or Deconjugated O -Methylated Catecholamine Metabolites by Eisenhofer, Graeme, Prejbisz, Aleksander, Peitzsch, Mirko, Pamporaki, Christina, Masjkur, Jimmy, Rogowski-Lehmann, Natalie, Langton, Katharina, Tsourdi, Elena, Pęczkowska, Mariola, Fliedner, Stephanie, Deutschbein, Timo, Megerle, Felix, Timmers, Henri J L M, Sinnott, Richard, Beuschlein, Felix, Fassnacht, Martin, Januszewicz, Andrzej, Lenders, Jacques W M

“…Measurements of plasma or urinary metanephrines are recommended for diagnosis of pheochromocytoma and paraganglioma (PPGL). What test offers optimal diagnostic…”
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Outcome of Bilateral Adrenalectomy in Cushing's Syndrome: A Systematic Review by Ritzel, Katrin, Beuschlein, Felix, Mickisch, Anne, Osswald, Andrea, Schneider, Harald J, Schopohl, Jochen, Reincke, Martin

“…Background: The outcome of bilateral adrenalectomy (BADx) in patients with Cushing's syndrome (CS) is not well characterized. Methods: A literature search was…”
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Integrated genomic characterization of adrenocortical carcinoma by Assié, Guillaume, Letouzé, Eric, Fassnacht, Martin, Jouinot, Anne, Luscap, Windy, Barreau, Olivia, Omeiri, Hanin, Rodriguez, Stéphanie, Perlemoine, Karine, René-Corail, Fernande, Elarouci, Nabila, Sbiera, Silviu, Kroiss, Matthias, Allolio, Bruno, Waldmann, Jens, Quinkler, Marcus, Mannelli, Massimo, Mantero, Franco, Papathomas, Thomas, De Krijger, Ronald, Tabarin, Antoine, Kerlan, Véronique, Baudin, Eric, Tissier, Frédérique, Dousset, Bertrand, Groussin, Lionel, Amar, Laurence, Clauser, Eric, Bertagna, Xavier, Ragazzon, Bruno, Beuschlein, Felix, Libé, Rossella, de Reyniès, Aurélien, Bertherat, Jérôme

“…Jérôme Bertherat, Aurélien de Reyniès and colleagues perform integrated genomic analyses of adrenocortical carcinomas. They discover recurrent alterations in…”
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Adrenal Function After Adrenalectomy for Subclinical Hypercortisolism and Cushing's Syndrome: A Systematic Review of the Literature by Di Dalmazi, Guido, Berr, Christina M, Fassnacht, Martin, Beuschlein, Felix, Reincke, Martin

“…Context: The postoperative course of patients with subclinical hypercortisolism (SH) is yet to be clarified. The aims are to review the prevalence and…”
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Endocrine disorders in patients with Fabry disease: insights from a reference centre prospective study by Bothou, Christina, Beuschlein, Felix, Nowak, Albina

“…Context Fabry Disease (FD) is a rare X-linked storage disease characterised by a-galactosidase A deficiency and diffuse organ accumulation of…”
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The impact of Connshing's syndrome - mild cortisol excess in primary aldosteronism drives diabetes risk by Beuschlein, Felix, Reincke, Martin, Arlt, Wiebke

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Prognosis of Malignant Pheochromocytoma and Paraganglioma (MAPP-Prono Study): A European Network for the Study of Adrenal Tumors Retrospective Study by Hescot, Segolene, Curras-Freixes, Maria, Deutschbein, Timo, van Berkel, Anouk, Vezzosi, Delphine, Amar, Laurence, de la Fouchardière, Christelle, Valdes, Nuria, Riccardi, Fernando, Do Cao, Christine, Bertherat, Jerome, Goichot, Bernard, Beuschlein, Felix, Drui, Delphine, Canu, Letizia, Niccoli, Patricia, Laboureau, Sandrine, Tabarin, Antoine, Leboulleux, Sophie, Calsina, Bruna, Libé, Rossella, Faggiano, Antongiulio, Schlumberger, Martin, Borson-Chazot, Francoise, Mannelli, Massimo, Gimenez-Roqueplo, Anne-Paule, Caron, Philippe, Timmers, Henri J L M, Fassnacht, Martin, Robledo, Mercedes, Borget, Isabelle, Baudin, Eric

“…Abstract Background Malignant pheochromocytoma and paraganglioma (MPP) are characterized by prognostic heterogeneity. Our objective was to look for prognostic…”
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Genetic Spectrum and Clinical Correlates of Somatic Mutations in Aldosterone-Producing Adenoma by Fernandes-Rosa, Fabio Luiz, Williams, Tracy Ann, Riester, Anna, Steichen, Olivier, Beuschlein, Felix, Boulkroun, Sheerazed, Strom, Tim M, Monticone, Silvia, Amar, Laurence, Meatchi, Tchao, Mantero, Franco, Cicala, Maria-Verena, Quinkler, Marcus, Fallo, Francesco, Allolio, Bruno, Bernini, Giampaolo, Maccario, Mauro, Giacchetti, Gilberta, Jeunemaitre, Xavier, Mulatero, Paolo, Reincke, Martin, Zennaro, Maria-Christina

“…Primary aldosteronism is the most common form of secondary hypertension. Somatic mutations in KCNJ5, ATP1A1, ATP2B3, and CACNA1D have been described in…”
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The role of regulated necrosis in endocrine diseases by Tonnus, Wulf, Belavgeni, Alexia, Beuschlein, Felix, Eisenhofer, Graeme, Fassnacht, Martin, Kroiss, Matthias, Krone, Nils P., Reincke, Martin, Bornstein, Stefan R., Linkermann, Andreas

“…The death of endocrine cells is involved in type 1 diabetes mellitus, autoimmunity, adrenopause and hypogonadotropism. Insights from research on basic cell…”
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Constitutive Activation of PKA Catalytic Subunit in Adrenal Cushing's Syndrome by Beuschlein, Felix, Fassnacht, Martin, Assié, Guillaume, Calebiro, Davide, Stratakis, Constantine A, Osswald, Andrea, Ronchi, Cristina L, Wieland, Thomas, Sbiera, Silviu, Faucz, Fabio R, Schaak, Katrin, Schmittfull, Anett, Schwarzmayr, Thomas, Barreau, Olivia, Vezzosi, Delphine, Rizk-Rabin, Marthe, Zabel, Ulrike, Szarek, Eva, Salpea, Paraskevi, Forlino, Antonella, Vetro, Annalisa, Zuffardi, Orsetta, Kisker, Caroline, Diener, Susanne, Meitinger, Thomas, Lohse, Martin J, Reincke, Martin, Bertherat, Jérome, Strom, Tim M, Allolio, Bruno

“…Corticotropin-independent Cushing's syndrome occurs with adrenocortical tumors or hyperplasia. The authors report that germline duplications of PRKACA lead to…”
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Major Prognostic Role of Ki67 in Localized Adrenocortical Carcinoma After Complete Resection by Beuschlein, Felix, Weigel, Jens, Saeger, Wolfgang, Kroiss, Matthias, Wild, Vanessa, Daffara, Fulvia, Libé, Rosella, Ardito, Arianna, Al Ghuzlan, Abir, Quinkler, Marcus, Oßwald, Andrea, Ronchi, Cristina L, de Krijger, Ronald, Feelders, Richard A, Waldmann, Jens, Willenberg, Holger S, Deutschbein, Timo, Stell, Anthony, Reincke, Martin, Papotti, Mauro, Baudin, Eric, Tissier, Frédérique, Haak, Harm R, Loli, Paola, Terzolo, Massimo, Allolio, Bruno, Müller, Hans-Helge, Fassnacht, Martin

“…Background: Recurrence of adrenocortical carcinoma (ACC) even after complete (R0) resection occurs frequently. Objective: The aim of this study was to identify…”
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Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension by Beuschlein, Felix, Boulkroun, Sheerazed, Osswald, Andrea, Wieland, Thomas, Nielsen, Hang N, Lichtenauer, Urs D, Penton, David, Schack, Vivien R, Amar, Laurence, Fischer, Evelyn, Walther, Anett, Tauber, Philipp, Schwarzmayr, Thomas, Diener, Susanne, Graf, Elisabeth, Allolio, Bruno, Samson-Couterie, Benoit, Benecke, Arndt, Quinkler, Marcus, Fallo, Francesco, Plouin, Pierre-Francois, Mantero, Franco, Meitinger, Thomas, Mulatero, Paolo, Jeunemaitre, Xavier, Warth, Richard, Vilsen, Bente, Zennaro, Maria-Christina, Strom, Tim M, Reincke, Martin

“…Felix Beuschlein, Martin Reincke and colleagues identify recurrent somatic mutations in ATP1A1 and ATP2B3 in aldosterone-producing adenomas with wild-type…”
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Characteristics of Pediatric vs Adult Pheochromocytomas and Paragangliomas by Pamporaki, Christina, Hamplova, Barbora, Peitzsch, Mirko, Prejbisz, Aleksander, Beuschlein, Felix, Timmers, Henri J.L.M., Fassnacht, Martin, Klink, Barbara, Lodish, Maya, Stratakis, Constantine A., Huebner, Angela, Fliedner, Stephanie, Robledo, Mercedes, Sinnott, Richard O., Januszewicz, Andrzej, Pacak, Karel, Eisenhofer, Graeme

“…Abstract Context: Pheochromocytomas and paragangliomas (PPGLs) in children are often hereditary and may present with different characteristics compared with…”
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