Search Results - "Beuscher, H"
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Constitutive Expression of Macrophage-Inflammatory Protein 2 (MIP-2) mRNA in Bone Marrow Gives Rise to Peripheral Neutrophils with Preformed MIP-2 Protein
Published in The Journal of immunology (1950) (15-10-2001)“…Macrophage-inflammatory protein 2 (MIP-2) is a major CXC chemokine involved in the migration of polymorphonuclear neutrophils (PMNs) to sites of inflammation…”
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A synthetic, non-peptide CXCR2 antagonist blocks MIP-2-induced neutrophil migration in mice
Published in Immunobiology (1979) (01-01-2004)“…Non-peptide antagonists of chemokine receptors are considered an intriguing alternative for the treatment of acute and chronic diseases. Particularly the…”
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Bacterial evasion of host immune defense: Yersinia enterocolitica encodes a suppressor for tumor necrosis factor alpha expression
Published in Infection and Immunity (01-04-1995)“…Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Differential regulation of cytokine and cytokine receptor mRNA expression upon infection of bone marrow-derived macrophages with Listeria monocytogenes
Published in Infection and Immunity (01-09-1996)“…Cytokine and cytokine receptor mRNA expression was analyzed by PCR-assisted amplification of RNA extracted from bone marrow-derived macrophages (BMMphi) at…”
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Neutralization of endogenous IL-6 suppresses induction of IL-1 receptor antagonist
Published in The Journal of immunology (1950) (15-04-1995)“…IL-1 is a potent cytokine that promotes host defense and inflammation. These processes may be modulated by an IL-1 receptor antagonist (IL-1Ra) that binds to…”
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IL-1 beta is secreted by activated murine macrophages as biologically inactive precursor
Published in The Journal of immunology (1950) (15-03-1990)“…IL-1 alpha and IL-beta are distinct cytokines, produced by activated macrophages. The temporal sequence in the processing and secretion as well as the…”
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Constitutive expression of CXCL2/MIP-2 is restricted to a Gr-1high, CD11b+, CD62Lhigh subset of bone marrow derived granulocytes
Published in International immunology (01-11-2004)“…CXCL2/macrophage inflammatory protein (MIP)-2 is an inducible murine chemokine involved in attraction of polymorphonuclear granulocytes to sites of infection…”
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Local extrahepatic expression of complement genes C3, factor B, C2, and C4 is increased in murine lupus nephritis
Published in The Journal of clinical investigation (01-11-1988)“…Systemic lupus erythematosus (SLE) is associated with the presence of complement proteins and immune complexes in affected organs. Since complement proteins…”
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Activation of bone marrow-derived mouse macrophages by bacterial lipopeptide: cytokine production, phagocytosis and Ia expression
Published in European journal of immunology (01-01-1990)“…The lipopeptide N-palmitoyl-S-(2,3-bis(palmitoyloxy)-(2RS)-propyl)-(R)-cysteinyl-a lanyl-glycine (Pam3Cys-Ala-Gly), a synthetic analogue of the N-terminal part…”
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Transition from interleukin 1β (IL-1β) to IL-1α production during maturation of inflammatory macrophages in vivo
Published in The Journal of experimental medicine (01-06-1992)“…In situ production of interleukin 1 alpha (IL-1 alpha) and IL-1 beta was investigated in Peyer's patches (PP) of mice undergoing an acute bacterial infection…”
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IL-1 serves as a secondary signal for IL-9 expression
Published in The Journal of immunology (1950) (01-12-1991)“…IL-9 is produced in vitro by activated CD4+ T cell lines of the Th2 subtype and by naive CD4+ T cells. Here we show that T cell lines stimulated with Con A in…”
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Analysis of the Yersinia enterocolitica 0:8 V antigen for cross protectivity
Published in Microbial pathogenesis (01-04-1999)“…The plasmid encoded V antigen (Vag) of pathogenic Yersinia spp. is a major virulence factor as well as a protective immunogen. Recently, two main types of Vag,…”
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Macrophage membrane interleukin 1 regulates the expression of acute phase proteins in human hepatoma Hep 3B cells
Published in The Journal of immunology (1950) (15-09-1987)“…To assess the potential role of membrane interleukin 1 (mIL-1) in modulating expression of acute phase proteins, we studied the effect of fixed mouse…”
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The precursor of interleukin-1 alpha is phosphorylated at residue serine 90
Published in The Journal of biological chemistry (15-03-1988)“…Mononuclear phagocytes release interleukin-1 (IL-1), a 17-kDa polypeptide with diverse biological activities. IL-1 is synthesized as a precursor (31 kDa) which…”
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Tumor necrosis factor-α expression induced by anti-YopB antibodies coincides with protection against Yersinia enterocolitica infection in mice
Published in Medical microbiology and immunology (01-03-1997)“…Previous studies have suggested that virulence of pathogenic Yersiniae is associated with a suppression of the local cytokine response. In this context, the…”
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Constitutive and IL 1-regulated murine complement gene expression is strain and tissue specific [published erratum appears in J Immunol 1987 Apr 15;138(8):2745]
Published in The Journal of immunology (1950) (01-02-1987)“…To study the molecular mechanisms accounting for strain- and tissue-specific variations in the production of complement proteins, complementary DNA probes were…”
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Suppression of TNF by V antigen of Yersinia spp. involves activated T cells
Published in European journal of immunology (01-04-1999)“…The 39‐kDa V antigen (Vag) of pathogenic Yersinia species has been described to be a potent suppressor of TNF production. The underlying cellular and molecular…”
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Formation of intrachain disulfide bonds gives rise to two different forms of the murine IL-1 beta precursor
Published in The Journal of immunology (1950) (01-05-1991)“…IL-1 beta is an inflammatory cytokine produced by activated macrophages. Secretion of IL-1 beta comprises a biologic inactive precursor (molecular mass = 31…”
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Studies on the release of cell-associated interleukin 1 by paraformaldehyde-treated murine macrophages
Published in European journal of immunology (01-10-1988)“…Experiments are presented demonstrating the release of interleukin 1 (IL1) by lipopolysaccharide-stimulated murine macrophages (M phi) after treatment of the…”
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