Search Results - "Beukes, Denzil R."

Antimicrobial Activity of the Secondary Metabolites Isolated from a South African Red Seaweed, Laurencia corymbosa by Fakee, Jameel, Bolton, John J, Le Roes-Hill, Marilize, Durrell, Kim A, Antunes, Edith, Beukes, Denzil R

“…South Africa's highly diverse marine biota includes several endemic marine red algae of the genus. Cryptic species and morphological variability make the…”
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South African actinobacteria: A treasure trove of novel bioactive metabolites for drug discovery by Acquah, Kojo S, Gammon, David W, Beukes, Denzil R

“…Although South Africa is known as one of the most biodiverse countries in the world, based on its unique plants and animals, microorganisms have received much…”
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Enhanced Antimicrobial and Anticancer Activity of Silver and Gold Nanoparticles Synthesised Using Sargassum incisifolium Aqueous Extracts by Mmola, Mokone, Roes-Hill, Marilize Le, Durrell, Kim, Bolton, John J, Sibuyi, Nicole, Meyer, Mervin E, Beukes, Denzil R, Antunes, Edith

“…A detailed, methodical approach was used to synthesise silver and gold nanoparticles using two differently prepared aqueous extracts of the brown algae . The…”
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Encapsulation of Variabilin in Stearic Acid Solid Lipid Nanoparticles Enhances Its Anticancer Activity in Vitro by Lerata, Mookho S, D'Souza, Sarah, Sibuyi, Nicole R S, Dube, Admire, Meyer, Mervin, Samaai, Toufiek, Antunes, Edith M, Beukes, Denzil R

“…The use of natural products as chemotherapeutic agents is well established; however, many of these are associated with undesirable side effects, including high…”
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Manniosides G-J, New Ursane- and Lupane-Type Saponins from Schefflera mannii (Hook.f.) Harms by Tonga, Simionne Lapoupée Kuitcha, Tchegnitegni, Billy Toussie, Siwe-Noundou, Xavier, Tsopmene, Ulrich Joël, Ponou, Beaudelaire Kemvoufo, Dzoyem, Jean Paul, Poka, Madan, Demana, Patrick H, Tapondjou, Léon Azefack, Beukes, Denzil R, Antunes, Edith M, Teponno, Rémy Bertrand

“…Four previously unreported triterpenoid saponins named 3β-hydroxy-23-oxours-12-en-28-oic acid 28- -β- -glucopyranosyl ester (mannioside G) ( ), 23-…”
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Green Synthesized sAuNPs as a Potential Delivery Platform for Cytotoxic Alkaloids by Mubaiwa, Byron, Lerata, Mookho S, Sibuyi, Nicole R S, Meyer, Mervin, Samaai, Toufiek, Bolton, John J, Antunes, Edith M, Beukes, Denzil R

“…The use of natural products as chemotherapeutic agents is well established. However, many are associated with undesirable side effects, including high toxicity…”
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Novel South African Rare Actinomycete Kribbella speibonae Strain SK5: A Prolific Producer of Hydroxamate Siderophores Including New Dehydroxylated Congeners by Acquah, Kojo Sekyi, Beukes, Denzil R, Warner, Digby F, Meyers, Paul R, Sunassee, Suthananda N, Maglangit, Fleurdeliz, Deng, Hai, Jaspars, Marcel, Gammon, David W

“…In this paper, we report on the chemistry of the rare South African Actinomycete strain SK5, a prolific producer of hydroxamate siderophores and their…”
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Seaweed-Derived Phenolic Compounds in Growth Promotion and Stress Alleviation in Plants by Aina, Omolola, Bakare, Olalekan Olanrewaju, Daniel, Augustine Innalegwu, Gokul, Arun, Beukes, Denzil R, Fadaka, Adewale Oluwaseun, Keyster, Marshall, Klein, Ashwil

“…Abiotic and biotic stress factors negatively influence the growth, yield, and nutritional value of economically important food and feed crops. These…”
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Colourful chemistry of South African latrunculid sponges by Samaai, Toufiek, Davies-Coleman, Michael T., Beukes, Denzil R., Antunes, Edith M.

“…Marine sponges – in common with many other sessile marine invertebrates seemingly devoid of obvious physical forms of defence against predators, e.g. spines or…”
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Identification of Antimycobacterial Natural Products from a Library of Marine Invertebrate Extracts by Acquah, Kojo Sekyi, Beukes, Denzil R, Seldon, Ronnett, Jordaan, Audrey, Sunassee, Suthananda N, Warner, Digby F, Gammon, David W

“…Tuberculosis (TB) remains a public health crisis, requiring the urgent identification of new anti-mycobacterial drugs. We screened several organic and aqueous…”
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Assessment of potential anti-cancer stem cell activity of marine algal compounds using an in vitro mammosphere assay by de la Mare, Jo-Anne, Sterrenberg, Jason N, Sukhthankar, Mugdha G, Chiwakata, Maynard T, Beukes, Denzil R, Blatch, Gregory L, Edkins, Adrienne L

“…The cancer stem cell (CSC) theory proposes that tumours arise from and are sustained by a subpopulation of cells with both cancer and stem cell properties. One…”
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In Vitro Evaluation of the Phytopharmacological Potential of Sargassum incisifolium for the Treatment of Inflammatory Bowel Diseases by Nyambe, Mutenta N, Koekemoer, Trevor C, van de Venter, Maryna, Goosen, Eleonora D, Beukes, Denzil R

“…Comprised of Crohn's disease and ulcerative colitis, inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the gastro-intestinal…”
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Semi-Synthesis and Evaluation of Sargahydroquinoic Acid Derivatives as Potential Antimalarial Agents by Munedzimwe, Tatenda C, van Zyl, Robyn L, Heslop, Donovan C, Edkins, Adrienne L, Beukes, Denzil R

“…Malaria continues to present a major health problem, especially in developing countries. The development of new antimalarial drugs to counter drug resistance…”
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Cytotoxic Pyrroloiminoquinones from Four New Species of South African Latrunculid Sponges by Antunes, Edith M, Beukes, Denzil R, Kelly, Michelle, Samaai, Toufiek, Barrows, Louis R, Marshall, Kathryn M, Sincich, Catherine, Davies-Coleman, Michael T

“…An examination of organic extracts of four new species of South African latrunculid sponges, Tsitsikamma pedunculata, T. favus, Latrunculia bellae, and…”
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Isolation and characterisation of altissimin: a novel cytotoxic flavonoid C-apioglucoside from Drimia altissima (Asparagaceae) by Nyambe, Mutenta N., Beukes, Denzil R., Van De Venter, Maryna, Swanepoel, Bresler, Hlangothi, Buyiswa G.

“…Flavonoids are a class of biologically active compounds with various proven nutraceutical benefits. In flavonoid C-glycosides, the aglycones are attached to…”
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Very Green Photosynthesis of Gold Nanoparticles by a Living Aquatic Plant: Photoreduction of Au III by the Seaweed Ulva armoricana by Mukhoro, Ofhani C, Roos, Wiets D, Jaffer, Mohammed, Bolton, John J, Stillman, Martin J, Beukes, Denzil R, Antunes, Edith

“…Light-assisted in vivo synthesis of gold nanoparticles (NPs) from aqueous solutions of dilute Au salts by a living green marine seaweed (Ulva armoricana) is…”
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Very Green Photosynthesis of Gold Nanoparticles by a Living Aquatic Plant: Photoreduction of AuIII by the Seaweed Ulva armoricana by Mukhoro, Ofhani C., Roos, Wiets D., Jaffer, Mohammed, Bolton, John J., Stillman, Martin J., Beukes, Denzil R., Antunes, Edith

“…Light‐assisted in vivo synthesis of gold nanoparticles (NPs) from aqueous solutions of dilute AuIII salts by a living green marine seaweed (Ulva armoricana) is…”
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Isolation, Characterization and Antiproliferative Activity of New Metabolites from the South African Endemic Red Algal Species Laurencia alfredensis by Dziwornu, Godwin A, Caira, Mino R, Mare, Jo-Anne de la, Edkins, Adrienne L, Bolton, John J, Beukes, Denzil R, Sunassee, Suthananda N

“…The marine red algae of the genus have been widely studied for their structurally diverse and biologically active secondary metabolites. We report here the…”
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Electrochemistry-guided isolation of antioxidant metabolites from Sargassum elegans by Ragubeer, Nasheen, Limson, Janice L., Beukes, Denzil R.

“…► Use of cyclic and square-wave voltammetry in the isolation of antioxidants. ► Guided by oxidation potential and area under anodic peak. ► Isolation of…”
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Identification and in vitro anti-esophageal cancer activity of a series of halogenated monoterpenes isolated from the South African seaweeds Plocamium suhrii and Plocamium cornutum by Antunes, Edith M., Afolayan, Anthonia F., Chiwakata, Maynard T., Fakee, Jameel, Knott, Michael G., Whibley, Catherine E., Hendricks, Denver T., Bolton, John J., Beukes, Denzil R.

“…The South African red seaweed Plocamium suhrii produces a series of unique halogenated monoterpenes. These compounds inhibit the growth of esophageal cancer…”
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