Search Results - "Beubler, Eckhard"
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Endothelium-derived prostaglandin I2 controls the migration of eosinophils
Published in Journal of allergy and clinical immunology (01-05-2010)“…Background Enhanced eosinophil migration from the blood into the tissue is a hallmark of allergic diseases. Prostaglandin (PG) I2 is the major prostanoid…”
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Immunogenicity, safety, and tolerability of the measles-vectored chikungunya virus vaccine MV-CHIK: a double-blind, randomised, placebo-controlled and active-controlled phase 2 trial
Published in The Lancet (British edition) (22-12-2018)“…Chikungunya fever is an emerging viral disease and substantial threat to public health. We aimed to assess the safety, tolerability, and immunogenicity of a…”
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5-HT2 and 5-HT3 receptor subtypes mediate cholera toxin-induced intestinal fluid secretion in the rat
Published in Gastroenterology (New York, N.Y. 1943) (01-07-1990)“…The mechanisms of diarrhea in Asiatic cholera have been studied extensively. Cyclic adenosine monophosphate, 5-hydroxytryptamine (5-HT), prostaglandins, and…”
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Cholera toxin induces prostaglandin synthesis via post-transcriptional activation of cyclooxygenase-2 in the rat jejunum
Published in The Journal of pharmacology and experimental therapeutics (01-06-2001)“…The mechanisms of diarrhea in Asiatic cholera have been studied extensively. Cyclic AMP, 5-hydroxytryptamine, prostaglandins, and the function of neuronal…”
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About the Therapy of Laryngotracheitis (Croup): Significance of Rectal Dosage Forms
Published in Pharmacology (01-06-2015)“…Glucocorticoids are drugs of choice for treatment of laryngotracheitis (croup). They may be administered orally as tablets or juice, locally as inhalation or…”
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Significance of nitric oxide in the stimulation of intestinal fluid absorption in the rat jejunum in vivo
Published in British journal of pharmacology (01-01-1995)“…1 The effects of inhibiting nitric oxide (NO)‐synthase on fluid transport, mucosal cyclic GMP and cyclic AMP levels and intraluminal prostaglandin E2…”
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Protein carbamylation renders high-density lipoprotein dysfunctional
Published in Antioxidants & redox signaling (15-06-2011)“…Carbamylation of proteins through reactive cyanate has been demonstrated to predict an increased cardiovascular risk. Cyanate is formed in vivo by breakdown of…”
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Involvement of K + channel modulation in the proabsorptive effect of nitric oxide in the rat jejunum in vivo
Published in European journal of pharmacology (05-12-1996)“…The role of K + channels in the mediation of the nitric oxide(NO)-induced proabsorptive effect in intestinal fluid transport was investigated in a functional…”
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Involvement of 5-hydroxytryptamine, prostaglandin E2, and cyclic adenosine monophosphate in cholera toxin-induced fluid secretion in the small intestine of the rat in vivo
Published in Gastroenterology (New York, N.Y. 1943) (01-02-1989)“…The diarrhea of cholera is considered to rely solely on a cyclic adenosine monophosphate-mediated secretory mechanism. However, both 5-hydroxytryptamine and…”
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Klebsiella oxytoca as a Causative Organism of Antibiotic-Associated Hemorrhagic Colitis
Published in The New England journal of medicine (07-12-2006)“…In this study, six patients received a diagnosis of antibiotic-associated hemorrhagic colitis and were negative for Clostridium difficile ; five were positive…”
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Pharmacokinetics of bilobalide, ginkgolide A and B after administration of three different Ginkgo biloba L. preparations in humans
Published in Phytotherapy research (01-03-2010)“…A sensitive LC-ESI-MS method with a solid-phase extraction was established for the determination of bilobalide, ginkgolide A and ginkgolide B in human plasma;…”
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Influence of the Surfactant Tyloxapol on Mucociliary Clearance in Human Respiratory Cystic Fibrosis Cells
Published in Pharmacology (01-06-2016)“…Dehydration of the apical surface of cystic fibrosis (CF) airway epithelia leads to a greatly impaired mucociliary clearance function in CF patients. In an in…”
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Significance of calcium for the prostaglandin E2-mediated secretory response to 5-hydroxytryptamine in the small intestine of the rat in vivo
Published in Gastroenterology (New York, N.Y. 1943) (01-06-1986)“…5-Hydroxytryptamine (5-HT) has been claimed to mediate intestinal secretion in morphine withdrawal diarrhea through stimulation of local prostaglandin…”
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Endothelium-derived prostaglandin I 2 controls the migration of eosinophils
Published in Journal of allergy and clinical immunology (01-05-2010)“…Enhanced eosinophil migration from the blood into the tissue is a hallmark of allergic diseases. Prostaglandin (PG) I 2 is the major prostanoid released by…”
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Opioide in der Rheumaschmerztherapie: Adäquate Schmerztherapie wird viel zu spät, zu niedrig dosiert oder gar nicht durchgeführt
Published in Rheuma plus (01-10-2011)“…Der Schmerz, der als Frühsymptom eine Warnfunktion ausübt, hat bei chronisch rheumatischen Schmerzen keine Bedeutung mehr, außer, dass er die Lebensqualität…”
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Colonic secretion mediated by prostaglandin E2 and 5-hydroxytryptamine may contribute to diarrhea due to morphine withdrawal in the rat
Published in Gastroenterology (New York, N.Y. 1943) (01-11-1984)“…Prostaglandins and cyclic adenosine monophosphate have been claimed to play a major role in the morphine withdrawal syndrome, but intestinal secretion has not…”
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Pharmacokinetics of the main alkamides after administration of three different Echinacea purpurea preparations in humans
Published in Planta medica (01-05-2008)“…Establishing the pharmacological basis for efficacy of herbal medicinal products (HMPs) is a continuous challenge. In this context, also the question of…”
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Pharmakologie der Cyclooxygenase‐2‐Inhibition
Published in Wiener medizinische Wochenschrift (01-03-2003)“…Zusammenfassung: Bei der Entstehung von Schmerz und Entzündung spielen die Prostaglandine eine wichtige, modulatorische Rolle. Beide Symptome, Schmerz und…”
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