Search Results - "Betzel, Ch"

Structural Basis of Phospholipase A2 Inhibition for the Synthesis of Prostaglandins by the Plant Alkaloid Aristolochic Acid from a 1.7 Å Crystal Structure by Chandra, Vikas, Jasti, Jayasankar, Kaur, Punit, Srinivasan, A, Betzel, Ch, Singh, T. P

“…This is the first structural observation of a plant product showing high affinity for phospholipase A2 and regulating the synthesis of arachidonic acid, an…”
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Crystal Structure of a Complex Formed between a Snake Venom Phospholipase A2 and a Potent Peptide Inhibitor Phe-Leu-Ser-Tyr-Lys at 1.8 Å Resolution by Chandra, Vikas, Jasti, Jayasankar, Kaur, Punit, Dey, Sharmistha, Perbandt, M., Srinivasan, A., Betzel, Ch, Singh, T.P.

“…Phospholipase A 2 is an important enzyme involved in the production of prostaglandins and their related compounds causing inflammatory disorders. Among the…”
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Enhancement of enzyme activity through three-phase partitioning: crystal structure of a modified serine proteinase at 1.5 Å resolution by Singh, R.K., Gourinath, S., Sharma, S., Roy, I., Gupta, M.N., Betzel, Ch, Srinivasan, A., Singh, T.P.

“…Three-phase partitioning is fast developing as a novel bioseparation strategy with a wide range of applications including enzyme stability and enhancement of…”
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Crystal structure of vipoxin at 2.0 Å: an example of regulation of a toxic function generated by molecular evolution by Perbandt, M, Wilson, J.C, Eschenburg, S, Mancheva, I, Aleksiev, B, Genov, N, Willingmann, P, Weber, W, Singh, T.P, Betzel, Ch

“…Vipoxin is the main toxic component in the venom of the Bulgarian snake Vipera ammodytes meridionalis, the most toxic snake in Europe. Vipoxin is a complex…”
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An Amylose Antiparallel Double Helix at Atomic Resolution by Hinrichs, W., Büttner, G., Steifa, M., Ch. Betzel, Zabel, V., Pfannemüller, B., Saenger, W.

“…In the crystal structure of the polyiodide complex (p-nitrophenyl-$\alpha $-maltohexaose$_{2}$). Ba(I$_{3}$)$_{2}\ \cdot $ 22H$_{2}$O, the maltohexaose units…”
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First structural evidence of a specific inhibition of phospholipase A2 by alpha-tocopherol (vitamin E) and its implications in inflammation: crystal structure of the complex formed between phospholipase A2 and alpha-tocopherol at 1.8 A resolution by Chandra, Vikas, Jasti, Jayasankar, Kaur, Punit, Betzel, Ch, Srinivasan, A, Singh, T P

“…This is the first structural evidence of alpha-tocopherol (alpha-TP) as a possible candidate against inflammation, as it inhibits phospholipase A2 specifically…”
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Synchrotron X-ray data collection and restrained least-squares refinement of the crystal structure of proteinase K at 1.5 A resolution by Betzel, C, Pal, G P, Saenger, W

“…The structure of the serine endopeptidase proteinase K (279 amino acid residues; 28,790 daltons) has been refined by restrained least-squares methods to a…”
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The crystal structure of a Thermus thermophilus tRNAGly acceptor stem microhelix at 1.6aa resolution by Oberthuer, D, Eichert, A, Erdmann, V A, Fuerste, JP, Betzel, Ch, Foerster, C

“…a-[ordm The tRNAGly/GlyRS system is a special case regarding protein structures and tRNA identity. a-[ordm This possibly reflects an evolutionary divergence of…”
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The crystal structure of a Thermus thermophilus tRNAGly acceptor stem microhelix at 1.6Å resolution by Oberthür, D., Eichert, A., Erdmann, V.A., Fürste, J.P., Betzel, Ch, Förster, C.

“…► The tRNAGly/GlyRS system is a special case regarding protein structures and tRNA identity. ► This possibly reflects an evolutionary divergence of the system…”
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Crystal structure of a human tRNA super(G) super(l) super(y) microhelix at 1.2A resolution by ster, C, Mankowska, M, Furste, J P, Perbandt, M, Betzel, Ch, Erdmann, V A

“…The tRNA super(G) super(l) super(y)/glycyl-tRNA synthetase (GlyRS) system belongs to the so-called 'class II aminoacyl-tRNA synthetase system' in which tRNA…”
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Comparative X-ray structure analysis of human and Escherichia coli tRNA super(G) super(l) super(y) acceptor stem microhelices by ster, C, Zerressen-Harte, A, Furste, J P, Perbandt, M, Betzel, Ch, Erdmann, V A

“…tRNA identity elements assure the correct aminoacylation of tRNAs by the aminoacyl-tRNA synthetases with the cognate amino acid. The tRNA super(G) super(l)…”
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Crystal structure of a human tRNAGly microhelix at 1.2 Å resolution by Förster, C., Mankowska, M., Fürste, J.P., Perbandt, M., Betzel, Ch, Erdmann, V.A.

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Comparative X-ray structure analysis of human and Escherichia coli tRNAGly acceptor stem microhelices by Förster, C., Zerressen-Harte, A., Fürste, J.P., Perbandt, M., Betzel, Ch, Erdmann, V.A.

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Comparative X-ray structure analysis of human and Escherichia coli tRNA Gly acceptor stem microhelices by Förster, C., Zerressen-Harte, A., Fürste, J.P., Perbandt, M., Betzel, Ch, Erdmann, V.A.

“…tRNA identity elements assure the correct aminoacylation of tRNAs by the aminoacyl-tRNA synthetases with the cognate amino acid. The tRNA Gly/glycyl-tRNA…”
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Crystal structure of a human tRNA Gly microhelix at 1.2 Å resolution by Förster, C., Mankowska, M., Fürste, J.P., Perbandt, M., Betzel, Ch, Erdmann, V.A.

“…The tRNA Gly/glycyl-tRNA synthetase (GlyRS) system belongs to the so-called ‘class II aminoacyl-tRNA synthetase system’ in which tRNA identity elements are…”
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Crystal structure of an Escherichia coli tRNA super(G) super(l) super(y) microhelix at 2.0A resolution by ster, C, Brauer, ABE, Perbandt, M, Lehmann, D, Furste, J P, Betzel, Ch, Erdmann, V A

“…tRNA identity elements determine the correct aminoacylation by the cognate aminoacyl-tRNA synthetase. In class II aminoacyl tRNA synthetase systems, tRNA…”
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Crystal structure of an Escherichia coli tRNAGly microhelix at 2.0 Å resolution by Förster, C., Brauer, A.B.E., Perbandt, M., Lehmann, D., Fürste, J.P., Betzel, Ch, Erdmann, V.A.

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Superposition of a tRNA super(S) super(e) super(r) acceptor stem microhelix into the seryl-tRNA synthetase complex by ster, C, Brauer, ABE, Furste, J P, Betzel, Ch, Weber, M, Cordes, F, Erdmann, V A

“…Aminoacyl-tRNA synthetases catalyze the formation of aminoacyl-tRNAs. Seryl-tRNA synthetase is a class II synthetase, which depends on rather few and simple…”
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High resolution structure of streptavidin in complex with a novel high affinity peptide tag mimicking the biotin binding motif by Perbandt, M., Bruns, O., Vallazza, M., Lamla, T., Betzel, Ch, Erdmann, V.A.

“…A novel peptide was designed which possesses nanomolar affinity of less than 20 nM for streptavidin. Therefore it was termed Nano‐tag and has been used as an…”
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Crystal structure of an Escherichia coli tRNA Gly microhelix at 2.0 Å resolution by Förster, C., Brauer, A.B.E., Perbandt, M., Lehmann, D., Fürste, J.P., Betzel, Ch, Erdmann, V.A.

“…tRNA identity elements determine the correct aminoacylation by the cognate aminoacyl-tRNA synthetase. In class II aminoacyl tRNA synthetase systems, tRNA…”
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